Immunological comparisons of integrin α(IIIbβ3) (GPIIb-IIIa) expressed on platelets and human erythroleukemia cells: Evidence for cell specific differences

Blood Cells, Molecules, and Diseases

Volumn 22, Issue 1, 1996, Pages 23-35

  Jennings, Lisa K ^a,c   Slack, Steven M ^b   Wall, C Denise ^a   Mondoro, Traci Heath ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b University of Memphis   (United States)

^c Coleman Bldg ^*  (United States)

Author keywords

GPIIb IIIa; HEL cells; Integrins; Platelets

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; FIBRINOGEN RECEPTOR; GLYCOPROTEIN IIB; GLYCOPROTEIN IIIA; INTEGRIN; MONOCLONAL ANTIBODY; RECEPTOR SUBUNIT;

ARTICLE; BINDING SITE; CELL SPECIFICITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ERYTHROLEUKEMIA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; THROMBOCYTE;

EID: 0030130972     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.1996.0005     Document Type: Article

References (37)

1. 1. Jennings LK, Phillips DR. Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex. J Biol Chem 257:10458-10466, 1982.
2. 2. Hynes RO. Integrins: A family of cell surface receptors. Cell 48:549-554, 1987.
3. 3. Bennett JS, Vilaire G, Cines DB. Identification of the fibrinogen receptor on human platelets by photoaffinity labeling. J Biol Chem 257:8049-8064, 1982.
4. 4. Bennett JS, Vilaire G. Exposure of platelet fibrinogen receptors by ADP and epinephrine. J Clin Invest 64:1393-1401, 1979.
5. 5. Marguerie GA, Plow EF, Edington TS. Human platelets possess an inducible and saturable receptor specific for fibrinogen. J Biol Chem 254:5357-5363, 1979.
6. 6. Plow EF, Ginsberg MH. Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets. J Biol Chem 256:9477-82, 1981.
7. 7. Ruggeri ZM, Bader R, DeMarco L. Glanzmann's thrombasthenia: Deficient binding of von Willebrand factor to thrombin-stimulated platelets. Proc Natl Acad Sci USA 79:6038-6041, 1982.
8. 8. Fujimoto T, Ohara S, Hawiger J. Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets. J Clin Invest 69:1212-1222, 1982.
9. 9. Pytela R, Pierschbacher MD, Ginsberg MH, Plow EF, Ruoslahti E. Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp-specific adhesion receptors. Science 231:1559-1562, 1986.
10. 10. Phillips DR, Charo IF, Parise LV, Fitzgerald LA. The platelet membrane glycoprotein IIb-IIIa complex. Blood 71:831-843, 1988.
11. 11. Poncz M, Eisman R, Heidenreich R, et al: Structure of the platelet membrane glycoprotein IIb: Homology to the α subunits of the vitronectin and fibronectin receptors. J Biol Chem 262:8476-8482, 1987.
12. 12. Zimrin AB, Eisman R, Vilaire G, Schwartz E, Bennett JS, Poncz M. A common subunit for two different membrane receptors. J Clin Invest 81:1470-1475, 1987.
13. 3 integrins: Comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells. J Cell Biol 113:451-461, 1991.
14. 14. Parise LV, Helgerson SL, Steiner B, Nannizzi L, Phillips DR. Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. J Biol Chem 262:12597-12602, 1987.
15. 15. Kouns WC, Wall CD, White MM, Fox CF, Jennings LK. A conformation-dependent epitope of human platelet glycoprotein IIIa. J Biol Chem 265: 20594-20601, 1990.
16. 16. Heath TL, Slack SM, White MM, et al: Thrombin hydrolysis of human GP IIb-IIIa upon complex activation. Blood78:138a, 1991.
17. 17. Sims PJ, Ginsberg MH, Plow EF, Shattil SJ. Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex. J Biol Chem 266:7345-7352, 1991.
18. 18. Frelinger Ad, Cohen I, Plow EF, et al: Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers. J Biol Chem 265:6346-6352, 1990.
19. 19. Frelinger Ad, Lam SC, Plow EF, Smith MA, Loftus JC, Ginsberg MH. Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion. J Biol Chem 263: 12397-12402, 1988.
20. 20. Kouns WC, Newman PJ, Puckett KJ, et al: Further characterization of the loop structure of platelet glycoprotein IIIa: partial mapping of functionally significant glycoprotein IIIa epitopes. Blood 78: 3215-3223, 1991.
21. 21. Slack SM, Wall CD, White MM, Turitto VT, Jennings LK. A monoclonal antibody to platelet glycoprotein (GP) IIb-IIIa that exhibits reduced reactivity to the peptide-occupied GP IIb-IIIa receptor. Thromb Haemostas 69:1316a, 1993.
22. 22. Loftus JC, Plow EF, Frelinger AD, et al: Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function. Proc Natl Acad Sci USA 84:7114-7118, 1987.
23. 23. Wall CD, Kiick DM, Jennings LK. Evidence for multiple conformations of GP IIb-IIIa which display varying ligand competency on resting platelets. Blood 80:128a, 1992.
24. 24. Coller BS, Peerschke El, Scudder LE, Sullivan CA. A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa. J Clin Invest 72:325-338, 1983.
25. 25. Coller BS. A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex. J Clin Invest 76:101-108, 1985.
26. 2+-dependent binding of a synthetic Arg-Gly-Asp (RGD) peptide to a single site on purified platelet glycoprotein IIb-IIIa complex. J Biol Chem 264: 13102-13108, 1989.
27. 27. Scatchard G. The attraction of proteins for small molecules and ions. Ann NY Acad Sci 51:660-672, 1949.
28. 28. Munson PJ, Robard D. A versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107:220-239, 1980
29. 29. Pagano M, Gauvreau K. Principles of Biostatistics. Belmont, Duxbury Press, 1993.
30. 30. Du XP, Plow EF, Frelinger AD, O'Toole TE, Loftus JC, Ginsberg MH. Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa). Cell 65:409-416, 1991.
31. 31. Painter RG, Prodouz KN, Gaarde W. Isolation of a subpopulation of glycoprotein IIb-IIIa from platelet membranes that is bound to membrane actin. J Cell Biol 100:652-657, 1985.
32. 32. Gartner TK, Bennett JS. The tetrapeptide analogue of the cell attachment site of fibronectin inhibits platelet aggregation and fibrinogen binding to activated platelets. J Biol Chem 260:11891-11896, 1985.
33. 33. Heath TL. Doctoral Dissertation. The University of Tennessee, 1994.
34. 34. Santoro SA, Lawing WJ. Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins. Cell 48:867-873, 1987.
35. 35. D'Souza SE, Ginsberg MH, Lam SC, Plow EF. Chemical cross-linking of arginyl-glycyl-aspartic acid peptides to an adhesion receptor on platelets. J Biol Chem 263:3943-3951, 1988.
36. 1 integrins from different cell types show different binding specificities. J Biol Chem 265:615-618, 1990.
37. 37. Wall CD, Studtmann KE, Herman-Petrin J, Docktor ME, Jennings LK. The GP IIb-IIIa monoclonal antibody D3 induces a conformation in GP IIb-IIIa that binds both soluble and immobilized fibrinogen on HEL cells. J Cell Biochem 16F:180a, 1992.