Fetal heart rate in trisomy 21 and other chromosomal abnormalities at 10-14 weeks of gestation

Ultrasound in Obstetrics and Gynecology

Volumn 7, Issue 4, 1996, Pages 239-244

  Hyett, J A ^a   Noble, P L ^a   Snijders, R J M ^a   Montenegro, N ^a   Nicolaides, K H ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Chromosomal abnormality; Fetal heart rate; Nuchal translucency thickness; Screening; Trisomy 21

Indexed keywords

ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME DISORDER; CROWN RUMP LENGTH; DOWN SYNDROME; ECHOGRAPHY; FEMALE; FETUS HEART; FIRST TRIMESTER PREGNANCY; HEART RATE; HUMAN; NECK; PATHOPHYSIOLOGY; PREGNANCY; SENSITIVITY AND SPECIFICITY;

CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; CROWN-RUMP LENGTH; DOWN SYNDROME; FEMALE; FETAL HEART; HEART RATE; HUMANS; NECK; PREGNANCY; PREGNANCY TRIMESTER, FIRST; SENSITIVITY AND SPECIFICITY; ULTRASONOGRAPHY, PRENATAL;

EID: 0030122566     PISSN: 09607692     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-0705.1996.07040239.x     Document Type: Article

References (16)

1. Nicolaides, K. H., Azar, G., Byrne, D., Mansur, C. and Marks, K. (1992). Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy. Br. Med. J., 304, 867-9
2. Pandya, P. P., Snijders, R. J. M., Johnson, S. P., Brizot, M. L. and Nicolaides, K. H. (1995). Screening for fetal trisomies by maternal age and fetal nuchal translucency thickness at 10-14 weeks of gestation. Br. J. Obstet. Gynaecol., 102, 957-62
3. Hyett, J. A., Moscoso, G. and Nicolaides, K. H. (1995). First trimester nuchal translucency and cardiac septal defects in fetuses with trisomy 21. Am. J. Obstet. Gynecol., 172, 1411-13
4. Hyett, J. A., Moscoso, G. and Nicolaides, K. H. (1995). Increased nuchal translucency in trisomy 21 fetuses: relation to narrowing of the aortic isthmus. Hum. Reprod., 10, 3049-51
5. Hyett, J. A., Moscoso, G. and Nicolaides, K. H. (1995). Cardiac defects in 1st trimester fetuses with trisomy 18. Fetal Diagn. Ther., 10, 381-6
6. Snijders, R. J. M., Sebire, N. J. and Nicolaides, K. H. (1995). Maternal age and gestational age-specific risk for chromosomal defects. Fetal Diagn. Ther., 10, 356-67
7. Robinson, H. P. and Shaw-Dunn, J. (1973). Fetal heart rates as determined by sonar in early pregnancy. J. Obstet. Gynaecol. Br. Commonw., 90, 805-9
8. Rempen, A. (1990). Diagnosis of viability in early pregnancy with vaginal sonography. J. Ultrasound Med., 9, 711-16
9. Wisser, J. and Dirschedl, P. (1994). Embryonic heart rate in dated human embryos. Early Hum. Dev., 37, 107-15
10. Wladimiroff, J. W. and Seelen, J. C. (1972). Fetal heart action in early pregnancy. Development of fetal vagal function. Eur. J. Obstet. Gynecol., 2, 55-63
11. Schats, R., Jansen, C. A. M. and Wladimiroff, J. W. (1990). Abnormal embryonic heart rate pattern in early pregnancy associated with Down's syndrome. Hum. Reprod., 5, 877-9
12. Van Lith, J. M. M., Visser, G. H. A., Mantingh, A. and Beekhuis, J. R. (1992). Fetal heart rate in early pregnancy and chromosomal disorders. Br. J. Obstet. Gynaecol., 99, 741-4
13. Chard, T. (1991). Biochemistry and endocrinology of the Down syndrome pregnancy. Ann. NY Acad. Sci., 626, 580-96
14. Hyett, J. A., Brizot, M. L., Von Kaisenberg, C., McKie, A. T., Farzaneh, F. and Nicolaides, K. H. (1996). Cardiac gene expression of atrial natriuretic peptide and brain natriuretic peptide in trisomic fetuses. Obstet. Gynecol., in press
15. Teitel, D. and Rudolph, A. M. (1985). Perinatal oxygen delivery and cardiac function. Adv. Paediatr., 32, 321-47
16. Rudolph, A. M. and Heymann, M. A. (1976). Cardiac output in the fetal lamb: the effects of spontaneous and induced changes of heart rate on right and left ventricular output. Am. J. Obstet. Gynecol., 124, 183-92