Mechanisms of acid injury in porcine gastroesophageal mucosa

American Journal of Veterinary Research

Volumn 57, Issue 4, 1996, Pages 564-573

  Argenzio, Robert A ^a   Eisemann, Joan ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; SUIDAE; SUS SCROFA;

ACETIC ACID DERIVATIVE; FATTY ACID; HYDROCHLORIC ACID;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; CELL MEMBRANE POTENTIAL; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DRUG EFFECT; ELECTROPHYSIOLOGY; ESOPHAGUS; ESOPHAGUS DISEASE; FEMALE; IN VITRO STUDY; MALE; MUCOSA; PATHOLOGY; PATHOPHYSIOLOGY; PH; PHYSIOLOGY; STOMACH MUCOSA; STOMACH ULCER; SWINE; ULCER;

ACETATES; ANALYSIS OF VARIANCE; ANIMALS; ELECTROPHYSIOLOGY; ESOPHAGEAL DISEASES; ESOPHAGUS; FATTY ACIDS, NONESTERIFIED; FEMALE; GASTRIC MUCOSA; HYDROCHLORIC ACID; HYDROGEN-ION CONCENTRATION; MALE; MEMBRANE POTENTIALS; MUCOUS MEMBRANE; STOMACH ULCER; SWINE; ULCER;

EID: 0030122068     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.1996.57.04.564     Document Type: Article

References (25)

1. O'Brien JJ. Gastric ulcers In: Leman AD, ed Diseases of swine. 6th ed. Ames, Iowa, Iowa State University Press, 1986, 723-736.
2. Huber WG, Wallin RF. Pathogenesis of porcine gastric ulcers. Am J Vet Res 1967,28.1455-1459
3. Embaye H, Thomlinson JR, Lawrence TLJ. Histopathology of oesophagogastric lesions in pigs J Comp Pathol 1990;103 253-264.
4. Hedde RD, Lindsey TO, Parish RC, et al. Effect of diet particle size and feeding of H2-receptor antagonists on gastric ulcers in swine. J Anim Sci 1985;61:179-186.
5. Muggenburg BA, Kowalczyk T, Reese NA, et al. Experimental production of gastric ulcers in swine by histamine in mineral oil-beeswax. Am J Vet Res 1966,27:292-299
6. Orlando RC Esophageal epithelial defense against acid injury. J Clin Gastroenterol 1991,13(Suppl 2) S1-55.
7. Flemstrom G Gastric and duodenal mucosal secretion of bicarbonate. In. Johnson LR, ed Physiology of the gastrointestinal tract. 3rd ed. New York: Raven Press, 1994,1285-1309
8. Argenzio RA, Southworth M. Sites of organic acid production and absorption in the gastrointestinal tract of the pig. Am J Physiol 1975;228:454-462
9. Dirkson G Acidosis. In. Phillipson AT, ed Physiology of digestion and metabolism in the ruminant. Newcastle Upon Tyne, England. Oriel, 1970;612-625.
10. Orlando RC, Bryson JC, Powell DW. Mechanism of H injury in rabbit esophageal epithelium. Am J Physiol 1984,246:G718-G724.
11. Argenzio RA, Meuten DJ. Short-chain fatty acids induce reversible injury of porcine colon. Dig Dis Sci 1991,36 1459-1468.
12. Holler H. Untersuchungen uber Sekret und Sekretion der Cardiarusenzone im magen des Schweines Zentralbl Veterinarmed [A] 1970;17A:685.
13. Silen W Gastric mucosal defense and repair. In. Johnson LR, ed. Physiology of the gastrointestinal tract. 2nd ed. New York: Raven Press, 1987;1055-1069.
14. Koefoed-Johnsen V, Ussing HH. The nature of the frog skin potential. Acta Physiol Scand 1958,42.198-310.
15. Chien W-J, Stevens CE. Coupled active transport of Na and Cl across forestomach epithelium Am J Physiol 1972,223:997-1003
16. Powell DW, Morris SM, Boyd DD. Water and electrolyte transport by rabbit esophagus Am J Physiol 1975;229:438-443
17. +-pump sites in frog skin. J Cell Biol 1977;73:88-96
18. Powell DW. Barrier function of epithelia. Am J Physiol 1981;241:G275-G288.
19. Orlando RC, Lacy ER, Tobey NA, et al. Barriers to paracellular permeability in rabbit esophageal epithelium. Gastroenterology 1992;102:910-923.
20. Carney CN, Orlando RC, Powell DW, et al. Morphologic alterations in early acid-induced epithelial injury of the rabbit esophagus. Lab Invest 1981;45:198-208
21. Orlando RC, Powell DW, Carney CN. Pathophysiology of acute acid injury in rabbit esophageal epithelium. J Clin Invest 1981; 68:286-293
22. Tobey NA, Orlando RC. Mechanisms of acid injury to rabbit esophageal epithelium Gastroenterology 1991,101:1220-1228
23. + channels effect of hyposmotic stress on channel activity. Gastroenterology 1993,104:417-426.
24. Goldstein JL, Watkins JL, Greager JA, et al. The esophageal mucosal resistance: structure and function of an unique gastrointestinal epithelial barrier J Lab Clin Med 1994,123.653-659
25. Snow JC, Goldstein JL, Schmidt LN, et al. Rabbit esophageal cells show regulatory volume decrease, ionic basis and effect of pH. Gastroenterology 1993,105:102-110