Endocrine regulation of food intake and body weight

Journal of Laboratory and Clinical Medicine

Volumn 127, Issue 4, 1996, Pages 328-332

  Figlewicz, D P ^a   Schwartz, M W ^b   Seeley, R J ^b   Chavez, M ^b   Baskin, D G ^b   Woods, S C ^b   Porte Jr , D ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; PEPTIDE;

ADIPOSE TISSUE; ANIMAL; BODY WEIGHT; BRAIN; EATING; ENDOCRINE GLAND; FEEDBACK SYSTEM; GENETICS; HUMAN; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

ADIPOSE TISSUE; ANIMALS; BODY WEIGHT; BRAIN; EATING; ENDOCRINE GLANDS; FEEDBACK; HUMANS; INSULIN; OBESITY; PEPTIDES;

EID: 0030116791     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(96)90179-1     Document Type: Review

References (43)

1. Woods SC, Strubbe JH. The psychobiology of meals. Psych Bull Rev 1994;1:141-55.
2. Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte D Jr. Insulin in the brain: a hormonal regulator of energy balance. Endo Rev 1992;13:387-414.
3. Woods SC, Chavez M, Park CR, et al. The evaluation of insulin as a metabolic signal influencing behavior via the brain. Neurosci Biobehav Rev (in press).
4. Weigle DS. Appetite and the regulation of body composition. FASEB J 1994;8:302-10.
5. Keesey RE, Powley TL. The regulation of body weight. Annu Rev Psychol 1986;37:109-33.
6. Woods SC, Gibbs J. The regulation of food intake by peptides. Ann NY Acad Sci 1989;575:236-43.
7. Smith GP, Gibbs J. The development and proof of the CCK hypothesis of satiety. In: Dourish CT, Cooper SJ, Iversen SD, Iversen LL, eds. Multiple CCK receptors in the CNS. Oxford: Oxford University Press, 1992:166-82.
8. Geary N. Pancreatic glucagon signals postprandial satiety. Neurosci Biobehav Rev 1990;14:323-8.
9. Flynn FR. Bombesin-like peptides in the regulation of ingestive behavior. Ann NY Acad Sci 1994;120-34.
10. Figlewicz DP, Sipols AJ, Porte D Jr., Woods SC, Liddle RA. Intraventricular CCK inhibits food intake and gastric emptying in the baboon. Am J Physiol 1989;256:R1313-7.
11. Figlewicz DP, Sipols AJ, Porte D Jr., Woods SC. IVT CCK-8 is more effective at decreasing meal size than IV CCK-8 in the baboon. Brain Res Bull 1989;22:849-52.
12. West DB, Fey D, Woods SC. CCK persistently suppresses meal size but not food intake in free-feeding rats. Am J Physiol 1984;246:R776-87.
13. Figlewicz DP, Lacour F, Sipols A, Porte D Jr., Woods SC. Gastroenteropancreatic peptides and the central nervous system. Ann Rev Physiol 1987;49:383-95.
14. Morley JE. Neuropeptide regulation of appetite and weight. Endo Rev 1987;8:256-87.
15. Stanley BG. Neuropeptide Y in multiple hypothalamic sites controls eating behavior, endocrine, and autonomic systems for energy balance. In: Colmers WF, Wahlestedt C, eds. The biology of neuropeptide Y and related peptides. Clifton, New Jersey: Humana Press, 1993:457-509.
16. Akabayashi A, Wahlestedt C, Alexander JT, Leibowitz SF. Specific inhibition of endogenous neuropeptide Y synthesis in arcuate nucleus by oligonucleotides suppresses feeding behavior and insulin secretion. Mol Brain Res 1994;21:55-61.
17. Zarjevski N, Cusin I, Vetter R, Rohner-Jeanrenaud F, Jeanrenaud B. Chronic intracerebroventricular neuropeptide Y administration to normal rats mimics hormonal and metabolic changes of obesity. Endocrinology 1993;133:1753-8.
18. Billington CJ, Briggs JE, Brace M, Levine AS. Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism. Am J Physiol 1991;206:R321-7.
19. Geracioti TD, Liddle RA. Impaired cholecystokinin secretion in bulimia nervosa. N Engl J Med 1988;319:683-8.
20. Zhang Y, Proenca R, Maffie M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-32.
21. McGowan MK, Andrews KM, Kelly J, Grossman SP. Effects of chronic intrahypothalamic infusion of insulin on food intake and diurnal meal patterning in the rat. Behav Neurosci 1990;104:373-85.
22. Woods SC, Lotter EC, McKay LD, Porte D Jr. Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature 1979;282:503-5.
23. Rothwell NJ, Stock MJ. Insulin and thermogenesis. Int J Obesity 1988;12:93-102.
24. Park C, Chavez M, Woods SC. IVT insulin decreases respiratory quotient in rats. Soc Neurosci Abstr 1992;18:939.
25. Ikeda H, West DB, Pustek JJ, et al. Intraventricular insulin reduces food intake and body weight of lean but not obese Zucker rats. Appetite 1986;7:381-6.
26. Arase K, Fisler JS, Shargill NS, York DA, Bray GA. Intracerebroventricular infusions of 3-OHB and insulin in a rat model of dietary obesity. Am J Physiol 1988;255:R974-81.
27. Bagdade JD, Bierman EL, Porte D Jr. The significance of basal insulin levels in the evaluation of the insulin response to glucose in diabetic and nondiabetic subjects. J Clin Invest 1967;46:1549-57.
28. Schwartz MW, Sipols AJ, Kahn SE, et al. Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. Am J Physiol 1990;259:E378-83.
29. Strubbe JH, Porte D Jr., Woods SC. Insulin responses and glucose levels in plasma and cerebrospinal fluid during fasting and refeeding in the rat. Physiol Behav 1988;44:205-8.
30. Steffens AB, Scheurink AJ, Porte D Jr., Woods SC. Penetration of peripheral glucose and insulin into cerebrospinal fluid in the rat. Am J Physiol 1988;255:R200-4.
31. Israel PA, Park CR, Schwartz MW, et al. Effect of diet-induced obesity and experimental hyperinsulinemia on insulin uptake into CSF of the rat. Brain Res Bull 1993;30:571-5.
32. Figlewicz DP, Sipols AJ, Seeley RJ, Chavez M, Woods SC, Porte D Jr. Intraventricular insulin enhances the meal-suppressive efficacy of intraventricular cholecystokinin octapeptide in the baboon. Behav Neurosci 1995;109:1-3.
33. Figlewicz DP, West D, Stein LJ, Woods SC, Porte D Jr. Insulin alters the sensitivity of baboons to CCK-induced single meal suppression. Am J Physiol 1986;250:R856-60.
34. Kermani R, Richardson RD, Chavez M, Woods SC. Central insulin potentiates the ability of corticotropin-releasing hormone to reduce meal size. Am J Physiol (in press).
35. Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte D Jr. Insulin and the central regulation of energy balance: update 1994. Endo Rev Monographs 1994;2:109-13.
36. Sipols AJ, Baskin DG, Schwartz MW. Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes 1995; 44:147-51.
37. Dallman MF, Strack AM, Akana SF, et al. Feast and famine: critical role of glucocorticoids with insulin in daily energy flow. Front Neuroendocrinol 1993;14:303-47.
38. Strack AM, Sebastian RJ, Schwartz MW, Dallman MF. Glucocorticoids and insulin: reciprocal signals for energy balance. Am J Physiol 1995;268:R142-7.
39. Reddy R, Menke JB, Hao E, et al. Equivalent levels of ob gene expression in adipose tissues of morbidly obese and lean patients. Proc Endo Soc 1995;535.
40. Wilding JPH, Gilbey SG, Bailey CJ, et al. Increased neuropeptide Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse. Endocrinology 1993;132:1939-44.
41. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 1995;269:546-9.
42. Pelleymounter MA, Cullen MJ, Baker MB, et al. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995;269:540-3.
43. Considine RV, Considine EL, Williams CJ, et al. Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity. J Clin Invest 1995;95: 2986-8.