-
1
-
-
0020539530
-
Acetoaminophen in chronic liver disease
-
Benson, G. D. 1983. Acetoaminophen in chronic liver disease. Clin. Pharmacol. Ther. 33: 95-101.
-
(1983)
Clin. Pharmacol. Ther.
, vol.33
, pp. 95-101
-
-
Benson, G.D.1
-
2
-
-
0022552857
-
Nutritional parameters that alter hepatic drug metabolism, conjugation, and toxicity
-
Bidlack, W. R., Brown, R. C., and Mohan, C. 1986. Nutritional parameters that alter hepatic drug metabolism, conjugation, and toxicity. Federation Proc. 35: 142-148.
-
(1986)
Federation Proc.
, vol.35
, pp. 142-148
-
-
Bidlack, W.R.1
Brown, R.C.2
Mohan, C.3
-
3
-
-
0002272830
-
The metabolism of aminophenols, o-formaminophenol, benzazole, 2-methyl- and 2-biphenyl-benzoxazoles and benzoxazolone in rabbit
-
Bray, H. G., Colowes, R. C., and Thorpe, W. V. 1952. The metabolism of aminophenols, o-formaminophenol, benzazole, 2-methyl-and 2-biphenyl-benzoxazoles and benzoxazolone in rabbit. Biochem. J. 51: 70-78.
-
(1952)
Biochem. J.
, vol.51
, pp. 70-78
-
-
Bray, H.G.1
Colowes, R.C.2
Thorpe, W.V.3
-
4
-
-
0002616596
-
The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-aminophenol (free and total conjugated) in biological fluids and tissues
-
Brodie, B. B. and Axelrod, J. J. 1948. The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-aminophenol (free and total conjugated) in biological fluids and tissues. J. Pharmac. Exp. Ther. 94: 22-28.
-
(1948)
J. Pharmac. Exp. Ther.
, vol.94
, pp. 22-28
-
-
Brodie, B.B.1
Axelrod, J.J.2
-
5
-
-
0343139336
-
Conjugation reactions
-
(Jenner, P. and Testa, B. eds.), Dekker, New York
-
Caldwell, J. 1980. Conjugation reactions. pp. 211-250. In: Concepts in Drug Metabolism (Jenner, P. and Testa, B. eds.), Dekker, New York.
-
(1980)
Concepts in Drug Metabolism
, pp. 211-250
-
-
Caldwell, J.1
-
6
-
-
0016156587
-
Studies on the lipid composition of the rat liver endoplasmic reticulum after induction with phenobarbital and 20-methylcholanthrene
-
Davison, S. C. and Wills, E. D. 1974. Studies on the lipid composition of the rat liver endoplasmic reticulum after induction with phenobarbital and 20-methylcholanthrene. Biochem. J. 140: 461-468.
-
(1974)
Biochem. J.
, vol.140
, pp. 461-468
-
-
Davison, S.C.1
Wills, E.D.2
-
7
-
-
0019483544
-
Conjugation of p-nitrophenol in hepatocytes isolated from streptozotocin diabetic rats
-
Eacho, P. I., Sweeny, D., and Weiner, M. 1981. Conjugation of p-nitrophenol in hepatocytes isolated from streptozotocin diabetic rats. J. Pharmacol. Exp. Ther. 218: 34-40.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.218
, pp. 34-40
-
-
Eacho, P.I.1
Sweeny, D.2
Weiner, M.3
-
8
-
-
0021253309
-
Kinetics of the formation and secretion of the aniline metabolite 4-aminophenol and its conjugates by isolated rat hepatocytes
-
Evelo, C. T. A., Versteegh, J. F. M., and Blaauboer, B. J. 1984. Kinetics of the formation and secretion of the aniline metabolite 4-aminophenol and its conjugates by isolated rat hepatocytes. Xenobiotica 14: 409-416.
-
(1984)
Xenobiotica
, vol.14
, pp. 409-416
-
-
Evelo, C.T.A.1
Versteegh, J.F.M.2
Blaauboer, B.J.3
-
9
-
-
0019390680
-
Hepatic and extrahepatic glucuronidation of lorazepam in the dog
-
Gerkens, J. F., Desmond, P., Schenker, S., and Branch, R. A. 1981. Hepatic and extrahepatic glucuronidation of lorazepam in the dog. Hepatology 1: 329-335.
-
(1981)
Hepatology
, vol.1
, pp. 329-335
-
-
Gerkens, J.F.1
Desmond, P.2
Schenker, S.3
Branch, R.A.4
-
10
-
-
0022622871
-
The effects of age and chronic liver disease on the elimination of temazepam
-
Ghabrial, H., Desmond, P. V., Watson, K. J. R., Harman, P. J., and Mashford, M. L. 1986. The effects of age and chronic liver disease on the elimination of temazepam. Eur. J. Clin. Pharmacol. 30: 93-97.
-
(1986)
Eur. J. Clin. Pharmacol.
, vol.30
, pp. 93-97
-
-
Ghabrial, H.1
Desmond, P.V.2
Watson, K.J.R.3
Harman, P.J.4
Mashford, M.L.5
-
11
-
-
0018145427
-
Metabolism of aniline in rats, pigs and sheep
-
Kao, K., Faulkner, J., and Bridges, J. W. 1978. Metabolism of aniline in rats, pigs and sheep. Drug Metab. Dispos. 6: 549-555.
-
(1978)
Drug Metab. Dispos.
, vol.6
, pp. 549-555
-
-
Kao, K.1
Faulkner, J.2
Bridges, J.W.3
-
12
-
-
0007189399
-
Further studies on the inhibition and stimulation of microsomal drug-metabolizing enzymes of rat liver by various compounds
-
Kato, R., Chiesara, E., and Vassanelli, P. 1964. Further studies on the inhibition and stimulation of microsomal drug-metabolizing enzymes of rat liver by various compounds. Biochem. Pharmacol. 13: 69-83.
-
(1964)
Biochem. Pharmacol.
, vol.13
, pp. 69-83
-
-
Kato, R.1
Chiesara, E.2
Vassanelli, P.3
-
13
-
-
0018189181
-
Antiepileptic drug development: I. History and a program for progress
-
Krall, R. L., Penry, J. K., Kupferberg, H. J., and Swinyard, E. A. 1978. Antiepileptic drug development: I. History and a program for progress. Epilepsia 19: 393-408.
-
(1978)
Epilepsia
, vol.19
, pp. 393-408
-
-
Krall, R.L.1
Penry, J.K.2
Kupferberg, H.J.3
Swinyard, E.A.4
-
14
-
-
84913378767
-
S-adenosyl-L-ethionine (SAMe) attenuates alcoholic-induced mitochondrial injury in the baboon
-
Submitted (Toronto, November 3-4) Abstract
-
Lieber, C. S., Decarli, L. M., Kim, C., Lowe, N., Sasaki, R., and Leo, M. A. 1988. S-adenosyl-L-ethionine (SAMe) attenuates alcoholic-induced mitochondrial injury in the baboon. Submitted to the Meeting of the International Association for the Study of the Liver (Toronto, November 3-4) [Abstract].
-
(1988)
Meeting of the International Association for the Study of the Liver
-
-
Lieber, C.S.1
Decarli, L.M.2
Kim, C.3
Lowe, N.4
Sasaki, R.5
Leo, M.A.6
-
15
-
-
0016723915
-
Stavation and phenobarbital treatment effects on drug hydroxylation and glucuronidation in the rat liver and small intestinal mucosa
-
Marios, M. and Matti, L. 1975. Stavation and phenobarbital treatment effects on drug hydroxylation and glucuronidation in the rat liver and small intestinal mucosa. Biochem. Pharmacol. 24: 1529-1535.
-
(1975)
Biochem. Pharmacol.
, vol.24
, pp. 1529-1535
-
-
Marios, M.1
Matti, L.2
-
16
-
-
0018081508
-
Renal necrosis, glutathione depletion, and convalent binding after acetaminophen
-
McMurtry, R. J., Snodgrass, W. R., and Mitchell, J. R. 1978. Renal necrosis, glutathione depletion, and convalent binding after acetaminophen. Toxicol. Appl. Pharmacol. 45: 87-100.
-
(1978)
Toxicol. Appl. Pharmacol.
, vol.45
, pp. 87-100
-
-
McMurtry, R.J.1
Snodgrass, W.R.2
Mitchell, J.R.3
-
17
-
-
0015748302
-
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism
-
Mitchell, J. R., Jollow, D. J., Potter, W. Z., Gillette, J. R., and Brodie, B. B. 1973. Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J. Pharmacol. Exp. Ther. 187: 185-194.
-
(1973)
J. Pharmacol. Exp. Ther.
, vol.187
, pp. 185-194
-
-
Mitchell, J.R.1
Jollow, D.J.2
Potter, W.Z.3
Gillette, J.R.4
Brodie, B.B.5
-
18
-
-
0018077397
-
Paracetamol metabolism and toxicity in isolated hepatocytes from rat and mouse
-
Moldeus, P. 1978. Paracetamol metabolism and toxicity in isolated hepatocytes from rat and mouse. Biochem. Pharmacol. 27: 2859-2863.
-
(1978)
Biochem. Pharmacol.
, vol.27
, pp. 2859-2863
-
-
Moldeus, P.1
-
19
-
-
0021146282
-
Impaired oxidation of debrisoquine in patients with perhexiline liver injury
-
Morgan, M. Y., Reshef, R., Shah, R. R., Oates, N. S., Smith, R. L., and Sherlock, S. 1984. Impaired oxidation of debrisoquine in patients with perhexiline liver injury. Gut 25: 1057-1064.
-
(1984)
Gut
, vol.25
, pp. 1057-1064
-
-
Morgan, M.Y.1
Reshef, R.2
Shah, R.R.3
Oates, N.S.4
Smith, R.L.5
Sherlock, S.6
-
20
-
-
0018652421
-
Multiple drug metabolism in hepatic subcellular fractions
-
Muakkassah, S. F., Lowery, G. L., and Bidlack, W. R. 1979. Multiple drug metabolism in hepatic subcellular fractions. Proc. West. Pharmacol. Soc. 22: 119-124.
-
(1979)
Proc. West. Pharmacol. Soc.
, vol.22
, pp. 119-124
-
-
Muakkassah, S.F.1
Lowery, G.L.2
Bidlack, W.R.3
-
21
-
-
0009293675
-
Glucuronidation and sulfation in vivo and in vitro: Selective inhibition of sulphation by drugs and deficiency of inorganic sulphate
-
(Aitio, A. ed.), Elsever/North Holland, Amsterdam
-
Mulder, G. A. and Meerman, J. H. N. 1978. Glucuronidation and sulfation in vivo and in vitro: Selective inhibition of sulphation by drugs and deficiency of inorganic sulphate. pp. 389-397, In: Conjugation Reaction in Drug Biotransformations (Aitio, A. ed.), Elsever/North Holland, Amsterdam.
-
(1978)
Conjugation Reaction in Drug Biotransformations
, pp. 389-397
-
-
Mulder, G.A.1
Meerman, J.H.N.2
-
22
-
-
85033749665
-
Method of metabolism experiments
-
(Hanano, M., Umemura, K., and Iga, T. eds.), Soft Science, Inc., Tokyo
-
Murata, S. and Shomura, T. 1985. Method of metabolism experiments. pp. 291-293, In: Applied Pharmacokinetics - Theory and Experiments - (Hanano, M., Umemura, K., and Iga, T. eds.), Soft Science, Inc., Tokyo.
-
(1985)
Applied Pharmacokinetics - Theory and Experiments
, pp. 291-293
-
-
Murata, S.1
Shomura, T.2
-
23
-
-
0028053742
-
Effects of phenobarbital on drug metabolizing enzymes and other biochemical parameters in rats with DL-ethionine-induced liver injury
-
Noguchi, M., Fujitsuka, T., Honda, K., and Kawai, Y. 1994. Effects of phenobarbital on drug metabolizing enzymes and other biochemical parameters in rats with DL-ethionine-induced liver injury. J. Toxicol. Sci. 19: 203-212.
-
(1994)
J. Toxicol. Sci.
, vol.19
, pp. 203-212
-
-
Noguchi, M.1
Fujitsuka, T.2
Honda, K.3
Kawai, Y.4
-
24
-
-
0027741372
-
Toxicokinetics of phenobarbital in rats with DL-ethionine-induced liver injury
-
Noguchi, M., Tanaka, K., Kuwamura, Y., Fukushima, T., and Kawai, Y. 1993. Toxicokinetics of phenobarbital in rats with DL-ethionine-induced liver injury. J. Toxicol. Sci. 18: 245-255.
-
(1993)
J. Toxicol. Sci.
, vol.18
, pp. 245-255
-
-
Noguchi, M.1
Tanaka, K.2
Kuwamura, Y.3
Fukushima, T.4
Kawai, Y.5
-
25
-
-
0019479202
-
Conjugation of p-nitrophenol in perfused rat liver. The effect of substrate concentration and carbohydrate reserves
-
Reinke, L. A., Belinsky, S. A., Evans, R. K., Kauffman, F. C., and Thurman, R. G. 1981. Conjugation of p-nitrophenol in perfused rat liver. The effect of substrate concentration and carbohydrate reserves. J. Pharmacol. Exp. Ther. 217: 863-870.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.217
, pp. 863-870
-
-
Reinke, L.A.1
Belinsky, S.A.2
Evans, R.K.3
Kauffman, F.C.4
Thurman, R.G.5
-
26
-
-
0015409143
-
2+ on enzyme dispersion of isolated, perafused liver
-
2+ on enzyme dispersion of isolated, perafused liver. Exp. Cell Res. 74: 450-454.
-
(1972)
Exp. Cell Res.
, vol.74
, pp. 450-454
-
-
Seglen, P.O.1
-
27
-
-
0015138603
-
Effects of L-pyrrolidone-5-carboxylate on hepatic adenosine triphosphate levels in the ethionine-treated rat
-
Shull, K. H. and Kisilevsky, R. 1971. Effects of L-pyrrolidone-5-carboxylate on hepatic adenosine triphosphate levels in the ethionine-treated rat. Biochem. Pharmacol. 20: 2781-2785.
-
(1971)
Biochem. Pharmacol.
, vol.20
, pp. 2781-2785
-
-
Shull, K.H.1
Kisilevsky, R.2
-
28
-
-
0015137607
-
Effect of protein-free diet on UDP-glucuronyltransferase and sulphotransferase activities in rat liver
-
Woodcock, B. G. and Wood, G. C. 1971. Effect of protein-free diet on UDP-glucuronyltransferase and sulphotransferase activities in rat liver. Biochem. Pharmacol. 20: 2703-2713.
-
(1971)
Biochem. Pharmacol.
, vol.20
, pp. 2703-2713
-
-
Woodcock, B.G.1
Wood, G.C.2
-
29
-
-
0027421729
-
Effect of nutritional obesity on the induction of CYP2B enzymes following phenobarbital treatment
-
Zannikos, P. N., Bandyopadhyay, A. M., Robertson, L. W., and Blouin, R. A. 1993. Effect of nutritional obesity on the induction of CYP2B enzymes following phenobarbital treatment. Drug Metab. Dispos. 21: 782-787.
-
(1993)
Drug Metab. Dispos.
, vol.21
, pp. 782-787
-
-
Zannikos, P.N.1
Bandyopadhyay, A.M.2
Robertson, L.W.3
Blouin, R.A.4
|