The role of DNA damage and repair in ultraviolet B radiation-induced immunomodulation: Relevance for human photocarcinogenesis

Photochemistry and Photobiology

Volumn 63, Issue 4, 1996, Pages 394-396

  Krutmann, Jean ^a   Ahrens, Constanze ^a   Roza, Len ^b   Arlett, Colin F ^c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b TNO   (Netherlands)

^c UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; PYRIMIDINE DIMER;

ANIMAL; DNA DAMAGE; DNA REPAIR; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; RADIATION EXPOSURE; RADIATION INJURY; REVIEW; SKIN TUMOR; ULTRAVIOLET RADIATION;

ANIMALS; DNA DAMAGE; DNA REPAIR; HUMANS; IMMUNE TOLERANCE; INTERCELLULAR ADHESION MOLECULE-1; NEOPLASMS, RADIATION-INDUCED; PYRIMIDINE DIMERS; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 0030115455     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1996.tb03053.x     Document Type: Article

References (27)

1. Krutmann, J. and C. A. Elmets (eds.) (1995) Photoimmunology. Blackwell Science, Oxford.
2. Kripke, M. L. (1974) Antigenicity of murine skin tumors induced by ultraviolet light. J. Natl Cancer Inst. 53, 1333-1336.
3. Kripke, M. L. (1981) Immunologic mechanisms in UV-radiation carcinogenesis. Adv. Cancer Res. 34, 69-106.
4. Daynes, R. A., E. J. Bernhard, M. F. Gurish and D. H. Lynch (1981) Experimental photoimmunology: immunologic ramifications of UV-induced carcinogenesis. J Invest. Dermatol. 77, 77-81.
5. Hoover, R. and J. F. Fraumeni (1973) Risk of cancer in renaltransplant recipients. Lancet 2, 55.
6. Hill, B. H. R. (1976) Immunosuppressive drug therapy as a potentiator of skin tumors in five patients with lymphoma. Aust. J. Dermatol. 17, 46-51.
7. Kinlen, L., A. Sheil, J. Peta and R. Doll (1979) Collaborative United Kingdom - Australian study of cancer in patients treated with immunosuppressive drugs. Br. J. Med. ii, 1461-1463.
8. Hartevelt, M. M., J. N. Bouver-Bacinck. A. M, Kootte, B. J. Vermeer and J. P. Vandenbroucke (1990) Incidence of skin cancer after renal transplantation in the Netherlands. Transplantation 49, 506-509.
9. Yoshikawa, T., V. Rae, W. Bruins-Slot, J.-W. van den Berg, J. R. Taylor and J. W. Streilein (1990) Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in man. J. Invest. Dermatol. 95, 530-534.
10. Streilein, J. W. (1992) Immunogenetic factors in skin cancer. N. Engl. J. Med. 325, 884-886.
11. Krutmann, J. and M. Grewe (1995) Involvement of cytokines, DNA damage, and reactive oxygen intermediates in ultraviolet radiation-induced modulation of intercellular adhesion molecule-1 expression. J. Invest. Dermatol. 105, 67S-70S.
12. Krutmann, J. and U. Trefzer (1993) Regulation of keratinocyte ICAM-1 expression by UV irradiation. Semin. Immunopathol. 13, 333-344.
13. Krutmann, J., E, Bohnert and E. G. Jung (1994) Evidence that DNA damage is a mediator in ultraviolet B radiation-induced inhibition of human gene expression: ultraviolet B radiation effects on intercellular adhesion molecule-1 (ICAM-I) expression. J. Invest. Dermatol. 102, 428-432.
14. Krutmann, J., A. Koeck, E. Schauer, F. Parlow, A. Moeller, A. Kapp, E. Foerster, E. Schoepf and T. A. Luger (1990) TNF beta and ultraviolet radiation are potent regulators of ICAM-I expression on human keratinocytes. J. Invest. Dermatol. 95, 127-131.
15. Norris, D. A., B. Lyons, M. H. Middleton, J. Y. Yohn and M. Kashihara-Sawami (1990) Ultraviolet radiation can either suppress or induce expression of intercellular adhesion molecule-1 (ICAM-I) on the surface of human keratinocytes. J. Invest. Dermatol. 95, 132-138.
16. Krutmann, J., I. U. Khan, R. S. Wallis, F. Zhang, K. A. Koehler, E. A. Rich, J. J. Ellner and C. A. Elmets (1990) Cell membrane is a major locus for ultraviolet B-induced alterations in accessory cells. J. Clin. Invest. 85, 1529-1536.
17. 2) in ultraviolet B radiation (UVBR)-induced inhibition of ICAM-I expression in human antigen presenting cells. J. Invest. Dermatol. 105, 498A.
18. Ahrens, C., M. Grewe, P. Clingen, M. H. L. Green, S. A. Harcourt, A. R. Lehmann, C. F. Arlett and J. Krutmann (1996) The role of DNA damage in ultraviolet B radiation (UVBR)-induced immunomodulation. Arch. Dermatol. Res. (In press)
19. Stege, H., M. Grewe, K. Gyufko, S. Grether-Beck, L. Roza and J. Krutmann (1995) Demonstration of the in-vivo relevance of ultraviolet B radiation (UVBR)-induced inhbition of keratinocyte ICAM-I expression. J. Invest. Dermatol. 104, 601A.
20. Stege, H., L. Roza and J. Krutmann (1996) Thymine dimer formation is causally related to ultraviolet B radiation (UVBR)-induced immunosuppression in vivo in human skin. Arch. Dermatol. Res. (In press)
21. Kripke, M. L., P. A. Cox. L. G. Alas and D. B. Yarosh (1992) Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice. Proc. Natl. Acad. Sci. USA 89, 7516-7520
22. Kraemer, K. H. and H. Slor (1984) Xeroderma pigmentosum. Clin. Dermatol. 2, 33-69
23. Lehmann, A. R. (1987) Cockayne's syndrome and trichothiodystrophy: defective repair without cancer. Cancer Rev. 7, 82-103.
24. Ahrens, C., M. Grewe, S. Grether-Beck, K. Gyufko, S. A Harcourt, A. R. Lehmann, C. F. Arlett and J. Krutmann (1995) Ultraviolet B radiation (UVBR)-induced immunosuppression is relevant for human photocarcinogenesis. J. Invest. Dermatol. 105, 498A.
25. Broughton, B. C., H. Steingrimsdottir, C, Weber and A. R. Lehmann (1994) Mutations in the xeroderma pigmentosum group D DNA repair/transcription gene in patients with trichothiodystrophy. Nature Genet. 7. 189-194.
26. Bootsma, D. and J. H. J. Hoeijmakers (1993) Engagement with transcription. Nature 363, 114-115.
27. Schaeffer, L., V. Moncollin, R. Roy, A. Staub, M. Mezzina, A. Sarasin, G. Weeden, J. H. J. Hoeijmakers, and J.-M. Egly (1994) The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor. EMBO J. 13, 2388-2392.