Lessons learned from xeroderma pigmentosum

Photochemistry and Photobiology

Volumn 63, Issue 4, 1996, Pages 420-422

  Kraemer, Kenneth H ^a  

^a NCl   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOTRETINOIN;

HUMAN; IMMUNOTHERAPY; IN VITRO STUDY; MUTATION; REVIEW; SKIN TUMOR; ULTRAVIOLET RADIATION; XERODERMA PIGMENTOSUM;

HUMANS; IMMUNOTHERAPY; ISOTRETINOIN; MUTATION; SKIN NEOPLASMS; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

EID: 0030115024     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1996.tb03060.x     Document Type: Article

References (19)

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2. Cleaver, J. E. and K. H. Kraemer (1995) Xeroderma pigmentosum and Cockayne syndrome. In The Metabolic and Molecular Bases of Inherited Disease (Edited by C. R. Scriver, A. L. Beaudet, W. S. Sly and D. Valle), pp. 4393-4419. McGraw-Hill, New York.
3. Kraemer, K. H., M.-M Lee, A. D. Andrews and W. C Lambert (1994) The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer: the xeroderma pigmentosum paradigm. Arch. Dermatol. 130, 1018-1021.
4. Seidman, M. M., K. Dixon, A. Razzaque, R. J. Zagursky and M. L. Herman (1985) A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells. Gene 38, 233-237.
5. Parris, C. N. and M. M. Seidman (1992) A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid. Gene 117, 1-5.
6. Bredberg, A., K. H Kraemer and M. M Seidman (1986) Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells Proc. Natl. Acad. Sci. USA 83, 8273-8277
7. Brash, D. E , S. Seetharam, K. H Kraemer, M. M. Seidman and A. Bredberg (1987) Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells. Proc. Natl. Acad. Sci. USA 84, 3782-3786.
8. Seetharam, S., M. Protić-Sabljić, M. M. Seidman and K. H. Kraemer (1987) Abnormal ultraviolet mutagenic spectrum in plasmid DNA replicated in cultured fibroblasts from a patient with the skin cancer-prone disease, xeroderma pigmentosum. J. Clin. Invest. 80, 1613-1617.
9. Waters, H. L., S. Seetharam, M. M. Seidman and K. H. Kraemer (1993) Ultraviolet hypermutability of a shuttle vector propagated in xeroderma pigmentosum variant cells. J. Invest. Dermatol. 101, 744-748.
10. Ziegler, A., D. J. Leffell, S. Kunala, H. W. Sharma, M. Gailani, J. A. Simon, A. J. Halperin, H. P. Baden, P. E. Shapiro, A. E. Bale and D. E. Brash (1993) Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proc. Natl. Acad. Sci. USA 90, 4216-4220.
11. Brash, D. E., J. A. Rudolph, J. A. Simon, A. Lin, G. J. McKenna, H. P. Baden, A. J. Halperin and J. Pontën (1991) A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc. Natl. Acad. Sci. USA 88, 10124-10128.
12. Dumaz, N., A. Stary, T. Soussi, L. Daya-Grosjean and A. Sarasin (1994) Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene. Mutat. Res. Fundam. Mol. Mech. Mutagen. 307, 375-386.
13. Dumaz, N., C. Drougard, A. Sarasin and L. Daya-Grosjean (1993) Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients. Proc. Natl. Acad. Sci. USA 90, 10529-10533.
14. Kraemer, K. H., M. Herlyn, S. H. Yuspa, W. H. Clark, Jr., G. K. Townsend, G. R. Neises and V. J. Hearing (1989) Reduced DNA repair in cultured melanocytes and nevus cells from a patient with xeroderma pigmentosum. Arch. Dermatol. 125, 263-268.
15. Norris, P. G., G. A. Limb, A. S. Hamblin, A. R. Lehmann, C. F. Arlett, J. Cole, A. P. Waugh and J. L. Hawk (1990) Immune function, mutant frequency, and cancer risk in the DNA repair defective genodermatoses xeroderma pigmentosum, Cockayne's syndrome, and trichothiodystrophy. J. Invest. Dermatol. 94, 94-100.
16. Gaspari, A. A., T. A. Fleisher and K. H. Kraemer (1993) Impaired interferon production and natural killer cell activation in patients with the skin cancer-prone disorder, xeroderma pigmentosum. J. Clin. Invest. 92, 1135-1142.
17. Turner, M. L. C., A. N. Moshell, D. W. Corbett, J. B. Stem, M J. Roth, J. DiGiovanna, T. D. Horn and K. H. Kraemer (1994) Clearing of melanoma in situ with intralesional interferon alfa in a patient with xeroderma pigmentosum. Arch. Dermatol. 130, 1491-1502.
18. Kraemer, K. H., J. J. DiGiovanna, A. N. Moshell, R. E. Tarone and G. L. Peck (1988) Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin. N. Engl. J. Med. 318, 1633-1637.
19. Kraemer, K H., J. J. DiGiovanna and G. L. Peck (1992) Chemoprevention of skin cancer in xeroderma pigmentosum. J. Dermatol. 19, 715-718.