메뉴 건너뛰기




Volumn 276, Issue 3, 1996, Pages 968-976

Tumor necrosis factor production in the perfused mouse liver and its pharmacological modulation by methylxanthines

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; METHYLXANTHINE; TUMOR NECROSIS FACTOR ALPHA; XANTHINE DERIVATIVE;

EID: 0030111451     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (83)
  • 1
    • 0028108372 scopus 로고
    • Inactivation of Kupffer cells prevents early alcohol-induced liver injury
    • ADACHI, Y., BRADFORD, B. U., GAO, W., BOJES, H. K. AND THURMAN, R. G.: Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20: 453-460, 1994.
    • (1994) Hepatology , vol.20 , pp. 453-460
    • Adachi, Y.1    Bradford, B.U.2    Gao, W.3    Bojes, H.K.4    Thurman, R.G.5
  • 3
    • 0026714712 scopus 로고
    • Influence of the xanthine derivate HWA 138 on endotoxin-related coagulation disturbances: Effects in non-sensitized vs D-galactosamine sensitized rats
    • BAHRAMI, S., REDL, H., BUURMAN, W. A. AND SCHLAG, G.: Influence of the xanthine derivate HWA 138 on endotoxin-related coagulation disturbances: Effects in non-sensitized vs D-galactosamine sensitized rats. Thromb. Haemostas. 4: 418-423, 1992.
    • (1992) Thromb. Haemostas. , vol.4 , pp. 418-423
    • Bahrami, S.1    Redl, H.2    Buurman, W.A.3    Schlag, G.4
  • 4
    • 0028967838 scopus 로고
    • Effect of agents which modify reticuloendothelial function on acute phalloidin-induced lethality and hepatotoxicity in mice
    • BARRIAULT, C., AUDET, M., YOUSEF, I. M. AND TUCHWEBER, B.: Effect of agents which modify reticuloendothelial function on acute phalloidin-induced lethality and hepatotoxicity in mice. Toxicol. Appl. Pharmacol. 131: 206-215, 1995.
    • (1995) Toxicol. Appl. Pharmacol. , vol.131 , pp. 206-215
    • Barriault, C.1    Audet, M.2    Yousef, I.M.3    Tuchweber, B.4
  • 5
    • 0025181717 scopus 로고
    • Immunocytology on microwave-fixed cells reveals rapid and agonist-specific changes in subcellular accumulation patterns for cAMP or cGMP
    • BARSONY, J. AND MARX, S. J : Immunocytology on microwave-fixed cells reveals rapid and agonist-specific changes in subcellular accumulation patterns for cAMP or cGMP. Proc. Natl. Acad. Sci. U.S.A. 87: 1188-1192, 1990.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 1188-1192
    • Barsony, J.1    Marx, S.J.2
  • 6
    • 0018874764 scopus 로고
    • An improved assay of cyclic 3′,5′-nucleotide phosphodiesterase with QAE sephadex A25
    • BAUER, A. C. AND SCHWABE, U.: An improved assay of cyclic 3′,5′-nucleotide phosphodiesterase with QAE sephadex A25. Naunyn-Schrniedeberg's Arch. Pharmacol. 311: 193-198, 1980.
    • (1980) Naunyn-Schrniedeberg's Arch. Pharmacol. , vol.311 , pp. 193-198
    • Bauer, A.C.1    Schwabe, U.2
  • 7
    • 0014873336 scopus 로고
    • Effects of xanthine derivatives on lipolysis and on adenosine 3′,5′-monophosphate phosphodiesterase activity
    • BEAVO, J. A., ROGERS, N. L., CROFFORD, O. B., HARDMAN, J. G., SUTHERLAND, E. W. AND NEWMAN, E. V.: Effects of xanthine derivatives on lipolysis and on adenosine 3′,5′-monophosphate phosphodiesterase activity. Mol. Phaimacol 6: 597-603, 1970.
    • (1970) Mol. Phaimacol , vol.6 , pp. 597-603
    • Beavo, J.A.1    Rogers, N.L.2    Crofford, O.B.3    Hardman, J.G.4    Sutherland, E.W.5    Newman, E.V.6
  • 9
    • 0022411888 scopus 로고
    • Passive immunization against cachectin/tumor necrosis factor protects mice from the lethal effect of endotoxin
    • Wash. DC
    • BEUTLER, B., MILSARK, I. W. AND CERAMI, A. C.: Passive immunization against cachectin/tumor necrosis factor protects mice from the lethal effect of endotoxin. Science (Wash. DC) 229: 869-871, 1985.
    • (1985) Science , vol.229 , pp. 869-871
    • Beutler, B.1    Milsark, I.W.2    Cerami, A.C.3
  • 10
    • 0020661054 scopus 로고
    • D-galactosamine liver injury: Absorption of endotoxin and protective effect of small bowel and colon resection in rabbits (41555)
    • CAMARA, D. S., CARUANA, J. A., SCHWARTZ, K A., MONTES, M. AND NOLAN, J. P.: D-galactosamine liver injury: Absorption of endotoxin and protective effect of small bowel and colon resection in rabbits (41555). Proc. Soc. Exp. Biol. Med 172: 255-259, 1983.
    • (1983) Proc. Soc. Exp. Biol. Med , vol.172 , pp. 255-259
    • Camara, D.S.1    Caruana, J.A.2    Schwartz, K.A.3    Montes, M.4    Nolan, J.P.5
  • 11
    • 0028894398 scopus 로고
    • The production of cytokines by polymorphonuclear neutrophus
    • CASSATELLA, M. A.: The production of cytokines by polymorphonuclear neutrophus Immunol. Today 16: 21-26, 1995.
    • (1995) Immunol. Today , vol.16 , pp. 21-26
    • Cassatella, M.A.1
  • 12
    • 0022004113 scopus 로고
    • D-galactosamine hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice
    • CHOJKIER, M. AND FIERER, J.: D-galactosamine hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice. Gastroenterology 88: 115-121, 1985.
    • (1985) Gastroenterology , vol.88 , pp. 115-121
    • Chojkier, M.1    Fierer, J.2
  • 14
    • 0025358131 scopus 로고
    • Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat
    • COLLETTI, L. M., REMICK, D. G., BURTCH, G. D., KUNKEL, S. L., STRIETER, R. M. AND CAMPBELL, D. A.: Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J. Clin. Invest. 85: 1936-1943, 1990.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1936-1943
    • Colletti, L.M.1    Remick, D.G.2    Burtch, G.D.3    Kunkel, S.L.4    Strieter, R.M.5    Campbell, D.A.6
  • 15
    • 0028034090 scopus 로고
    • Effects of prostacyclin analogs on the synthesis of tissue factor, tumor necrosis factor-α and interleukin-1-β in human monocytic THP-1 cells
    • CRUTCHLEY, D. J., CONANAN, L. B. AND QUE, B. G.: Effects of prostacyclin analogs on the synthesis of tissue factor, tumor necrosis factor-α and interleukin-1-β in human monocytic THP-1 cells. J. Pharmacol. Exp. Ther. 271: 446-451, 1994.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 446-451
    • Crutchley, D.J.1    Conanan, L.B.2    Que, B.G.3
  • 16
    • 0023229234 scopus 로고
    • Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes
    • CUTURI, M. C , MURPHY, M., COSTA-GIOMI, M. P., WEINMANN, R., PERUSSIA, B. AND TRINCHIERI, G.: Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes. J. Exp. Med. 165: 1581-1594, 1987.
    • (1987) J. Exp. Med. , vol.165 , pp. 1581-1594
    • Cuturi, M.C.1    Murphy, M.2    Costa-Giomi, M.P.3    Weinmann, R.4    Perussia, B.5    Trinchieri, G.6
  • 17
    • 0028215199 scopus 로고
    • Lipopolysaccharide-neutralizing antibody reduces hepatocyte injury from acute hepatotoxin administration
    • CZAJA, M. J., XU, J., JU, Y., ALT, E. AND SCHMIEDEBERG, P.: Lipopolysaccharide-neutralizing antibody reduces hepatocyte injury from acute hepatotoxin administration. Hepatology 19: 1282-1289, 1994.
    • (1994) Hepatology , vol.19 , pp. 1282-1289
    • Czaja, M.J.1    Xu, J.2    Ju, Y.3    Alt, E.4    Schmiedeberg, P.5
  • 18
    • 0025051058 scopus 로고
    • Biologically active products of stimulated liver macrophages (Kupffer Cells)
    • DECKER, K.: Biologically active products of stimulated liver macrophages (Kupffer Cells). Eur. J. Biochem. 192: 245-261, 1990.
    • (1990) Eur. J. Biochem. , vol.192 , pp. 245-261
    • Decker, K.1
  • 19
    • 0024505693 scopus 로고
    • Comparative study of cytotoxicity, tumor necrosis factor, and protaglandin release after stimulation of rat Kupffer cells, murine Kupffer cells and murine inflammatory liver macrophages
    • DECKER, T., LOHMANN-MATHES, M. L., KARCK, U., PETERS, T. AND DECKER, K.: Comparative study of cytotoxicity, tumor necrosis factor, and protaglandin release after stimulation of rat Kupffer cells, murine Kupffer cells and murine inflammatory liver macrophages. J. Leukocyte Biol. 45: 139-146, 1989.
    • (1989) J. Leukocyte Biol. , vol.45 , pp. 139-146
    • Decker, T.1    Lohmann-Mathes, M.L.2    Karck, U.3    Peters, T.4    Decker, K.5
  • 21
    • 0026026007 scopus 로고
    • Cyclic nucleotides differentially regulate the synthesis of tumor necrosis-factor-alpha and interleukin-1-beta by human mononuclear cells
    • ENDRES, S., FÜLLE, H. J., SINHA, B., STOLL, D., DINARELLO, C. A., GERZER, R. AND WEBER, P. C.: Cyclic nucleotides differentially regulate the synthesis of tumor necrosis-factor-alpha and interleukin-1-beta by human mononuclear cells. Immunology 72: 56-60, 1991.
    • (1991) Immunology , vol.72 , pp. 56-60
    • Endres, S.1    Fülle, H.J.2    Sinha, B.3    Stoll, D.4    Dinarello, C.A.5    Gerzer, R.6    Weber, P.C.7
  • 22
    • 0022972464 scopus 로고
    • A highly sensitive cell line WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes
    • ESPEVIK, T. AND NISSEN-MEYER, J.: A highly sensitive cell line WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J. Immunol. Methods 95: 99-105, 1986.
    • (1986) J. Immunol. Methods , vol.95 , pp. 99-105
    • Espevik, T.1    Nissen-Meyer, J.2
  • 23
    • 0027175996 scopus 로고
    • Protection by phosphodiesterase inhibitors against endotoxin-induced liver injury in galactosamine-sensitized mice
    • FISCHER, W., SCHUDT, C. AND WENDEL, A.: Protection by phosphodiesterase inhibitors against endotoxin-induced liver injury in galactosamine-sensitized mice. Biochem. Pharmacol. 45: 2399-2404, 1993.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 2399-2404
    • Fischer, W.1    Schudt, C.2    Wendel, A.3
  • 24
    • 0022612671 scopus 로고
    • Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin
    • FREUDENBERG, M. A., KEPPLER, D. AND GALANOS, C.: Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect. Immun. 51: 891-895, 1986.
    • (1986) Infect. Immun. , vol.51 , pp. 891-895
    • Freudenberg, M.A.1    Keppler, D.2    Galanos, C.3
  • 25
    • 0000352873 scopus 로고
    • Galactosamine-induced sensitization to the lethal effects of endotoxin
    • GALANOS, C., FREUDENBERG, M. A. AND REUTTER, W.: Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc. Natl. Acad. Sci. U.S.A. 76: 5939-5943, 1979.
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 5939-5943
    • Galanos, C.1    Freudenberg, M.A.2    Reutter, W.3
  • 26
    • 0029048073 scopus 로고
    • Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice
    • GANTNER, F., LEIST, M., JILG, S., GERMANN, P. G., FREUDENBERG, M. A. AND TIEGS, G.: Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice. Gastroenterology 109:166-176, 1995a.
    • (1995) Gastroenterology , vol.109 , pp. 166-176
    • Gantner, F.1    Leist, M.2    Jilg, S.3    Germann, P.G.4    Freudenberg, M.A.5    Tiegs, G.6
  • 27
    • 0028795171 scopus 로고
    • Concanavalin A-induced T Cell-mediated hepatic injury in mice: The role of tumor necrosis factor
    • GANTNER, F., LEIST, M., LOHSE, A. W., GERMANN, P. G. AND TIEGS, G.: Concanavalin A-induced T Cell-mediated hepatic injury in mice: The role of tumor necrosis factor. Hepatology 21: 190-198, 1995b.
    • (1995) Hepatology , vol.21 , pp. 190-198
    • Gantner, F.1    Leist, M.2    Lohse, A.W.3    Germann, P.G.4    Tiegs, G.5
  • 28
    • 0026656340 scopus 로고
    • The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia
    • GIROIR, B. P., JOHNSON, J. A., BROWN, T., ALLEN, G. AND BEUTLER, B.: The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia. J. Clin. Invest. 90: 693-698, 1992.
    • (1992) J. Clin. Invest. , vol.90 , pp. 693-698
    • Giroir, B.P.1    Johnson, J.A.2    Brown, T.3    Allen, G.4    Beutler, B.5
  • 30
    • 0023189866 scopus 로고
    • Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria
    • Wash. DC
    • GRAU, G. E., FAJARDO, L. F., PIGUET, P. F., ALLETT, B. AND VASSALLI, P.: Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science (Wash. DC) 237: 1210-1212, 1987.
    • (1987) Science , vol.237 , pp. 1210-1212
    • Grau, G.E.1    Fajardo, L.F.2    Piguet, P.F.3    Allett, B.4    Vassalli, P.5
  • 31
    • 0017355502 scopus 로고
    • Significance of endotoxemia in experimental "galactosamine-hepatitis" in rat
    • GRÜN, M. AND LIEHR, H.: Significance of endotoxemia in experimental "galactosamine-hepatitis" in rat Acta Hepato-Gastroenterol. 23: 64-81, 1976.
    • (1976) Acta Hepato-Gastroenterol. , vol.23 , pp. 64-81
    • Grün, M.1    Liehr, H.2
  • 32
    • 0025282043 scopus 로고
    • Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signalling pathway
    • HAN, J., THOPSON, P. AND BEUTLER, B.: Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signalling pathway. J. Exp. Med. 172: 391-394, 1990.
    • (1990) J. Exp. Med. , vol.172 , pp. 391-394
    • Han, J.1    Thopson, P.2    Beutler, B.3
  • 33
    • 0027992143 scopus 로고
    • The role of tumor necrosis factor alpha in acute endotoxin-induced hepatotoxicity in ethanol-fed rats
    • HANSEN, J., CHERWITZ, D. L. AND ALLEN, J. I.: The role of tumor necrosis factor alpha in acute endotoxin-induced hepatotoxicity in ethanol-fed rats. Hepatology 20: 461-474, 1994.
    • (1994) Hepatology , vol.20 , pp. 461-474
    • Hansen, J.1    Cherwitz, D.L.2    Allen, J.I.3
  • 35
    • 0026326801 scopus 로고
    • Solcoseryl prevents inflammatory and hypoxic but not toxic liver damage in rodents
    • HARTUNG, T., LEIST, M., TIEGS, G., BASCHONG, W. AND WENDEL, A.: Solcoseryl prevents inflammatory and hypoxic but not toxic liver damage in rodents. Inflammopharmacology 1: 49-60, 1991.
    • (1991) Inflammopharmacology , vol.1 , pp. 49-60
    • Hartung, T.1    Leist, M.2    Tiegs, G.3    Baschong, W.4    Wendel, A.5
  • 36
    • 0025913258 scopus 로고
    • Endotoxin-inducible cytotoxicity in liver cell cultures-I
    • HARTUNG, T. AND WENDEL, A.: Endotoxin-inducible cytotoxicity in liver cell cultures-I. Biochem. Pharmacol. 42: 1129-1135, 1991.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 1129-1135
    • Hartung, T.1    Wendel, A.2
  • 37
    • 2642664447 scopus 로고
    • Role of adenylate cyclase in immunologic release of mediators from rat mast cells: Agonist and antagonist effects of purine- and ribose-modified adenosine analogs
    • HOLGATE, S. T., LEWIS, R. A. AND AUSTEN, K. F.: Role of adenylate cyclase in immunologic release of mediators from rat mast cells: Agonist and antagonist effects of purine- and ribose-modified adenosine analogs. Proc. Natl. Acad. Sci U.S.A. 77: 6800-6804, 1980.
    • (1980) Proc. Natl. Acad. Sci U.S.A. , vol.77 , pp. 6800-6804
    • Holgate, S.T.1    Lewis, R.A.2    Austen, K.F.3
  • 38
    • 0028858833 scopus 로고
    • Role of Kupffer cells in rat liver injury induced by diethyldithiocarbamate
    • ISHIYAMA, H., OGINO, K. AND HOBARA, T.: Role of Kupffer cells in rat liver injury induced by diethyldithiocarbamate. Eur. J. Pharmacol. 292: 135-141, 1995.
    • (1995) Eur. J. Pharmacol. , vol.292 , pp. 135-141
    • Ishiyama, H.1    Ogino, K.2    Hobara, T.3
  • 42
    • 0025666366 scopus 로고
    • Nonparenchymal cells and hepatotoxicity
    • LASKIN, D. L: Nonparenchymal cells and hepatotoxicity. Semin. Liver Dis 10: 293-304, 1990.
    • (1990) Semin. Liver Dis , vol.10 , pp. 293-304
    • Laskin, D.L.1
  • 43
    • 0028948724 scopus 로고
    • Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen
    • LASKIN, D. L., GARDNER, C R., PRICE, V. F. AND JOLLOW, D. J.: Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. Hepatology 21: 1045-1050, 1995.
    • (1995) Hepatology , vol.21 , pp. 1045-1050
    • Laskin, D.L.1    Gardner, C.R.2    Price, V.F.3    Jollow, D.J.4
  • 44
    • 0023175468 scopus 로고
    • Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosaminetreated mice
    • LEHMANN, V., FREUDENBERG, M. A. AND GALANOS, C.: Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosaminetreated mice. J. Exp. Med. 163: 657-663, 1987.
    • (1987) J. Exp. Med. , vol.163 , pp. 657-663
    • Lehmann, V.1    Freudenberg, M.A.2    Galanos, C.3
  • 45
    • 0028999453 scopus 로고
    • Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models
    • LEIST, M., GANTNER, F , BOHLINGER, I , TIEGS, G., GERMANN, P. G. AND WENDEL, A.: Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am. J. Pathol. 146: 1220-1234, 1995a.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1220-1234
    • Leist, M.1    Gantner, F.2    Bohlinger, I.3    Tiegs, G.4    Germann, P.G.5    Wendel, A.6
  • 46
    • 0028895940 scopus 로고
    • Activation of the 55 kDa TNF-receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis and nitrite release
    • LEIST, M., GANTNER, F., JILG, S. AND WENDEL, A.: Activation of the 55 kDa TNF-receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis and nitrite release. J. Immunol. 154: 1307-1316, 1995b.
    • (1995) J. Immunol. , vol.154 , pp. 1307-1316
    • Leist, M.1    Gantner, F.2    Jilg, S.3    Wendel, A.4
  • 47
    • 0028169333 scopus 로고
    • Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria
    • MCGUIRE, W., HILL, A. V. S., ALLSOPP, C. E. M., GREENWOOD, B. M. AND KJATKOWSKI, D. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature (Lond) 371: 508-511, 1994.
    • (1994) Nature (Lond) , vol.371 , pp. 508-511
    • Mcguire, W.1    Hill, A.V.S.2    Allsopp, C.E.M.3    And, G.B.M.4    Kjatkowski, D.5
  • 48
    • 0027289326 scopus 로고
    • Cytokine down-regulation in endotoxin tolerance
    • NGOZZI, M. AND GHEZZI, P., Cytokine down-regulation in endotoxin tolerance. Eur. Cytokine Network 4: 89-98, 1993.
    • (1993) Eur. Cytokine Network , vol.4 , pp. 89-98
    • Ngozzi, M.1    Ghezzi, P.2
  • 49
    • 0016374484 scopus 로고
    • Analogs of cyclic AMP and cyclic GMP: General methods of synthesis and the relationship of structure to enzymic activity
    • MEYER, R. B. AND MILLER, J. P.: Analogs of cyclic AMP and cyclic GMP: General methods of synthesis and the relationship of structure to enzymic activity. Life Sci. 14: 1019-1040, 1974.
    • (1974) Life Sci. , vol.14 , pp. 1019-1040
    • Meyer, R.B.1    Miller, J.P.2
  • 51
    • 0028236896 scopus 로고
    • Use of reverse transcription-polymerase chain reaction to evaluate in vivo cytokine gene expression in rats fed ethanol for long periods
    • NANJI, A. A., ZHAO, S., SADRZADEH, S. M. H. AND WAXMAN, D. J.: Use of reverse transcription-polymerase chain reaction to evaluate in vivo cytokine gene expression in rats fed ethanol for long periods. Hepatology 19: 1483-1487, 1994.
    • (1994) Hepatology , vol.19 , pp. 1483-1487
    • Nanji, A.A.1    Zhao, S.2    Sadrzadeh, S.M.H.3    Waxman, D.J.4
  • 52
    • 0027944823 scopus 로고
    • Pentoxifylline in vivo down-regulates the release of IL-1 beta, IL-6, IL-8 and tumor necrosis factor-alpha by human peripheral blood mononoclear cells
    • NEUNER, P., KLOSNER, G., SCHAUER, E., POURMOJIB, M., MACHETNEH, W., GRUNWALD, C., KNOBLER, R., SCHWARZ, A., LUGER, T. A. AND SCHWARZ, T.: Pentoxifylline in vivo down-regulates the release of IL-1 beta, IL-6, IL-8 and tumor necrosis factor-alpha by human peripheral blood mononoclear cells. Immunology 83: 262-267, 1994.
    • (1994) Immunology , vol.83 , pp. 262-267
    • Neuner, P.1    Klosner, G.2    Schauer, E.3    Pourmojib, M.4    Machetneh, W.5    Grunwald, C.6    Knobler, R.7    Schwarz, A.8    Luger, T.A.9    Schwarz, T.10
  • 53
    • 0026008409 scopus 로고
    • Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes
    • NICHOLSON, C. D., CHALISS, R. A. J. AND SHAHID, M.: Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes. Trends Pharmacol. Sci. 12: 19-27, 1991.
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 19-27
    • Nicholson, C.D.1    Chaliss, R.A.J.2    Shahid, M.3
  • 54
    • 0026720375 scopus 로고
    • A novel xanthine derivative counteracting in vivo tumor necrosis factor alpha toxicity in mice
    • NIEHÖRSTER, M., SCHÖNHARTING, M. AND WENDEL, A.: A novel xanthine derivative counteracting in vivo tumor necrosis factor alpha toxicity in mice. Circ. Shock 37: 270-273, 1992.
    • (1992) Circ. Shock , vol.37 , pp. 270-273
    • Niehörster, M.1    Schönharting, M.2    Wendel, A.3
  • 55
    • 0017864453 scopus 로고
    • Endotoxin and the liver. III. Modification of acute carbon tetrachloride injury by polymyxin B - An antiendotoxin
    • NOLAN, J. P. AND LEIBOWITZ, A. I.: Endotoxin and the liver. III. Modification of acute carbon tetrachloride injury by polymyxin B - An antiendotoxin. Gastroenterology 75: 445-449, 1978.
    • (1978) Gastroenterology , vol.75 , pp. 445-449
    • Nolan, J.P.1    Leibowitz, A.I.2
  • 56
    • 0027982098 scopus 로고
    • Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction
    • OZMEN, L., PERICIN, M., HAKIMI, J., CHIZZONITE, R. A., WYSOCKA, M., TRINCHIERI, G., GATELY, M. AND GAROTTA, G.: Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction. J. Exp. Med. 180: 907-915, 1994.
    • (1994) J. Exp. Med. , vol.180 , pp. 907-915
    • Ozmen, L.1    Pericin, M.2    Hakimi, J.3    Chizzonite, R.A.4    Wysocka, M.5    Trinchieri, G.6    Gately, M.7    Garotta, G.8
  • 57
    • 0027181961 scopus 로고
    • Adenosine and related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge
    • PARMELY, M. J., ZHOU, W., EDWARDS, C. K., BORCHERDING, D. R., SILVERSTEIN, R. AND MORRISON, D. C.: Adenosine and related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge. J. Immunol. 151: 389-396, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 389-396
    • Parmely, M.J.1    Zhou, W.2    Edwards, C.K.3    Borcherding, D.R.4    Silverstein, R.5    Morrison, D.C.6
  • 58
    • 0023041566 scopus 로고
    • Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, gamma-interferon and interleukin-1
    • PHILIP, R. AND EPSTEOT, L. B.: Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, gamma-interferon and interleukin-1. Nature (Lond) 323: 86-88, 1986.
    • (1986) Nature (Lond) , vol.323 , pp. 86-88
    • Philip, R.1    Epsteot, L.B.2
  • 59
  • 60
    • 0028134973 scopus 로고
    • Characterization of cAMP-dependent inhibition of LPS-induced TNF alpha production by rolipram, a specific phosphodiesterase IV (PDE IV) inhibitor
    • PRABHAKAR, U., LIPSHUTZ, D., BARTUS, J. O., SLIVJAK, M. J., SMITH, E. F., LEE, J. C. AND ESSER, K. M.: Characterization of cAMP-dependent inhibition of LPS-induced TNF alpha production by rolipram, a specific phosphodiesterase IV (PDE IV) inhibitor. Int. J. Immunopharmacol. 16: 805-816, 1994.
    • (1994) Int. J. Immunopharmacol. , vol.16 , pp. 805-816
    • Prabhakar, U.1    Lipshutz, D.2    Bartus, J.O.3    Slivjak, M.J.4    Smith, E.F.5    Lee, J.C.6    Esser, K.M.7
  • 61
    • 0019519389 scopus 로고
    • Compartmentalization of cyclic AMP during phagocytosis by human neutrophilic granulocytes
    • Wash.
    • PRYZWANSKY, K. B., STEINER, A. L., SPITZNAGEL, J. K. AND KAPOOR, C. L.: Compartmentalization of cyclic AMP during phagocytosis by human neutrophilic granulocytes, Science (Wash.) 211: 407-410, 1981.
    • (1981) Science , vol.211 , pp. 407-410
    • Pryzwansky, K.B.1    Steiner, A.L.2    Spitznagel, J.K.3    Kapoor, C.L.4
  • 62
    • 0025013013 scopus 로고
    • The biology and clinical applications of interleukin-2
    • REES, R. C AND WILTROUT, R. H.: The biology and clinical applications of interleukin-2. Immunol. Today 11: 36-38, 1990.
    • (1990) Immunol. Today , vol.11 , pp. 36-38
    • Rees, R.C.1    Wiltrout, R.H.2
  • 64
    • 0023720096 scopus 로고
    • Release of tumor necrosis factor-alpha from macrophages. Enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides
    • RENZ, H., GONG, J., SCHMITT, A., NAIN, M AND GEMSA, D.: Release of tumor necrosis factor-alpha from macrophages. Enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides. J. Immunol. 141: 2388-2393, 1988.
    • (1988) J. Immunol. , vol.141 , pp. 2388-2393
    • Renz, H.1    Gong, J.2    Schmitt, A.3    Nain, M.4    Gemsa, D.5
  • 65
    • 0040318163 scopus 로고
    • Central role of macrophages in the host response to endotoxin
    • ed. by D. Schlessinger, American Society of Microbiology, Washington
    • ROSENSTREICH, D. L. AND VOGEL, S. N.: Central role of macrophages in the host response to endotoxin. In Microbiology, ed. by D. Schlessinger, pp. 11-15, American Society of Microbiology, Washington, 1980.
    • (1980) Microbiology , pp. 11-15
    • Rosenstreich, D.L.1    Vogel, S.N.2
  • 66
    • 0024810472 scopus 로고
    • The role of prostacyclin in the protective effect of pentoxifylline and other xanthine derivatives in endotoxin action in mice
    • HADE, U. F.: The role of prostacyclin in the protective effect of pentoxifylline and other xanthine derivatives in endotoxin action in mice. Eicosanoids 2: 183-188, 1989.
    • (1989) Eicosanoids , vol.2 , pp. 183-188
    • Hade, U.F.1
  • 67
    • 0026642365 scopus 로고
    • Differential effects of pentoxifylline on the production of tumor necrosis factor-alpha and interleukin-6 by monocytes and T cells
    • SCHANDENÉ, L., VANDENBUSSCHE, P., CRUSIAUX, A., ALLÈGRE, M., ABRAMOWICZ, D., DUPONT, E., CONTENT, J. AND GOLDMAN, M.: Differential effects of pentoxifylline on the production of tumor necrosis factor-alpha and interleukin-6 by monocytes and T cells. Immunology 76: 30-34, 1992.
    • (1992) Immunology , vol.76 , pp. 30-34
    • Schandené, L.1    Vandenbussche, P.2    Crusiaux, A.3    Allègre, M.4    Abramowicz, D.5    Dupont, E.6    Content, J.7    Goldman, M.8
  • 68
    • 0024587485 scopus 로고
    • The effect of pentoxifylline in septic shock: New pharmacologic aspects of an established drug
    • SCHÖNHARTING, M. M. AND SCHADE, U. F.: The effect of pentoxifylline in septic shock: New pharmacologic aspects of an established drug. J. Med. 20: 97-105, 1989.
    • (1989) J. Med. , vol.20 , pp. 97-105
    • Schönharting, M.M.1    Schade, U.F.2
  • 69
    • 0026354677 scopus 로고
    • Influence of selective phosphodiesterase inhibitors on human neutrophil functions and levels of cAMP and Ca(i)
    • SCHUDT, C., WINDER, S., FORDERKUNZ, S., HATZELMANN, A. AND ULLRICH, V.: Influence of selective phosphodiesterase inhibitors on human neutrophil functions and levels of cAMP and Ca(i). Naunyn-Schmiedeberg's Arch. Pharmacol. 344: 682-690, 1991a.
    • (1991) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.344 , pp. 682-690
    • Schudt, C.1    Winder, S.2    Forderkunz, S.3    Hatzelmann, A.4    Ullrich, V.5
  • 70
    • 0025832697 scopus 로고
    • Zardaverine as a selective inhibitor of phosphodiesterase isozymes
    • SCHUDT, C., WINDER, S., MÜLLER, B. AND UKENA, D.: Zardaverine as a selective inhibitor of phosphodiesterase isozymes. Biochem. Pharmacol. 42: 153-162, 1991b.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 153-162
    • Schudt, C.1    Winder, S.2    Müller, B.3    Ukena, D.4
  • 71
    • 0027447078 scopus 로고
    • Xanthine derivatives: Comparison between suppression of tumor necrosis factor-alpha production and inhibition of cAMP phosphodiesterase activity
    • SEMMLER, J., GEBERT, U., EISENHUT, T., MOELLER, J., SCHOENHARTING;, M. M., ALLÉRA, A. AND ENDRES, S.: Xanthine derivatives: Comparison between suppression of tumor necrosis factor-alpha production and inhibition of cAMP phosphodiesterase activity. Immunology 78: 520-525, 1993.
    • (1993) Immunology , vol.78 , pp. 520-525
    • Semmler, J.1    Gebert, U.2    Eisenhut, T.3    Moeller, J.4    Schoenharting, M.M.5    Alléra, A.6    Endres, S.7
  • 72
    • 0028206668 scopus 로고
    • Role of activated macrophages in augmentation of endotoxin hepatotoxicity
    • SHIBAYAMA, Y., ASAKA, S. AND NAKATA, K.: Role of activated macrophages in augmentation of endotoxin hepatotoxicity. Exp. Toxicol. Pathol. 45: 497-502, 1993.
    • (1993) Exp. Toxicol. Pathol. , vol.45 , pp. 497-502
    • Shibayama, Y.1    Asaka, S.2    Nakata, K.3
  • 74
    • 0028221705 scopus 로고
    • Prevention of orthotopic liver allograft rejection in rats with a short-term brequinar sodium therapy
    • SHIRWAN, H., COSENZA, C. A., WANG, H. K., WU, G , MAKOWKA, L. AND CRAMER, D. V.: Prevention of orthotopic liver allograft rejection in rats with a short-term brequinar sodium therapy. Transplantation 57: 1072-1080, 1994.
    • (1994) Transplantation , vol.57 , pp. 1072-1080
    • Shirwan, H.1    Cosenza, C.A.2    Wang, H.K.3    Wu, G.4    Makowka, L.5    Cramer, D.V.6
  • 75
    • 0028954442 scopus 로고
    • Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids
    • SINHA, B., SEMMLER, J., EISENHUT, T., EIGLER, A. AND ENDRES, S.: Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids. Eur. J. Immunol. 25: 147-153, 1995.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 147-153
    • Sinha, B.1    Semmler, J.2    Eisenhut, T.3    Eigler, A.4    Endres, S.5
  • 77
    • 0018339413 scopus 로고
    • Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme
    • THOMPSON, W. J. AND APPLEMAN, M. M.: Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme. Adv. Cycl. Nucl. Res. 10: 69-92, 1979.
    • (1979) Adv. Cycl. Nucl. Res. , vol.10 , pp. 69-92
    • Thompson, W.J.1    Appleman, M.M.2
  • 78
    • 0026643743 scopus 로고
    • AT cell-dependent experimental liver injury in mice inducible to concanavalin A
    • TIEGS, G., HENTSCHEL, J. AND WENDEL, A.: AT cell-dependent experimental liver injury in mice inducible to concanavalin A. J. Clin. Invest. 90: 196-203, 1992.
    • (1992) J. Clin. Invest. , vol.90 , pp. 196-203
    • Tiegs, G.1    Hentschel, J.2    Wendel, A.3
  • 79
    • 0024589094 scopus 로고
    • Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice
    • TIEGS, G., WOLTER, M. AND WENDEL, A.: Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. Biochem. Pharmacol. 38: 627-631, 1989.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 627-631
    • Tiegs, G.1    Wolter, M.2    Wendel, A.3
  • 80
    • 0027333425 scopus 로고
    • Tumor necrosis factor, other cytokines and disease
    • TRACEY, K. J. AND CERAMI, A.: Tumor necrosis factor, other cytokines and disease. Annu. Rev. Cell. Biol. 9: 317-343, 1993.
    • (1993) Annu. Rev. Cell. Biol. , vol.9 , pp. 317-343
    • Tracey, K.J.1    Cerami, A.2
  • 81
    • 0025117386 scopus 로고
    • Studies on the hepatotoxicity of galactosamine/ endotoxin or galaetosamine/TNF in the perfused mouse liver
    • WANG, J. F. AND WENDEL, A.: Studies on the hepatotoxicity of galactosamine/ endotoxin or galaetosamine/TNF in the perfused mouse liver. Biochem. Pharmacol. 39: 267-270, 1990.
    • (1990) Biochem. Pharmacol. , vol.39 , pp. 267-270
    • Wang, J.F.1    Wendel, A.2
  • 82
    • 0023216053 scopus 로고
    • Evidence for the involvement of a reperfusion injury in galactosamine/endotoxin-induced hepatitis in mice
    • WENDEL, A., TIEGS, G. AND WERNER, C.: Evidence for the involvement of a reperfusion injury in galactosamine/endotoxin-induced hepatitis in mice. Biochem. Pharmacol. 36: 2637-2639, 1987.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 2637-2639
    • Wendel, A.1    Tiegs, G.2    Werner, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.