The protective effect of N-acetylcysteine on UVB-lnduced lmmunosuppression by inhibition of the action of Cis-urocanic acid

Photochemistry and Photobiology

Volumn 63, Issue 3, 1996, Pages 322-327

  Hemelaar, Peter J ^a   Beijersbergen Van Henegouwen, Gerard M J ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

UCA; ANIMALIA;

ACETYLCYSTEINE; SUNSCREEN; UROCANIC ACID;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CONTACT DERMATITIS; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MALE; MOUSE; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

ACETYLCYSTEINE; ANIMALS; DERMATITIS, CONTACT; IMMUNE TOLERANCE; MALE; MICE; MICE, INBRED BALB C; SUNSCREENING AGENTS; ULTRAVIOLET RAYS; UROCANIC ACID;

EID: 0030111266     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1996.tb03034.x     Document Type: Article

References (45)

1. Fisher, M. S. and M. L. Kripke (1977) Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesis. Proc. Natl. Acad. Sci. USA 47, 1688-1692.
2. Greene, M. I., M. S. Sy, M. L. Kripke and B. Benacerraf (1979) Impairment of antigen-presenting cell function by ultraviolet radiation. Proc. Natl Acad. Sci. USA 76, 6591-6595.
3. Howie, S., M. Norval and J. Maingay (1986) Exposure to low-dose ultraviolet radiation suppresses delayed-type hypersensitivity to Herpes simplex virus in mice. J. Invest. Dermatol. 86, 125-128.
4. Noonan, F. P., E. C. De Fabo and M. L. Kripke (1981) Suppression of contact hypersensitivity by UV radiation and its relationship to UV-induced suppression of tumor immunity. Photochem. Photobiol. 34, 683-689.
5. De Fabo, E. C. and F. P. Noonan (1983) Mechanism of immune suppression by ultraviolet irradiation in vivo: I. Evidence for the existence of a unique photoreceptor in skin and its role in photoimmunology. J. Exp. Med. 157, 84-98.
6. Jeevan, A. and M. L. Kripke (1989) Effect of a single exposure to ultraviolet radiation on Mycobacterium bovis bacillus calmette-guerin infection in mice. J. Immunol. 143, 2837-2843.
7. Denkins, Y., I. J. Fidler and M. L. Kripke (1989) Exposure of mice to UV-B radiation suppresses delayed hypersensitivity to Candida albicans. Photochem. Photobiol. 49, 615-619.
8. Morison, W. L. and S. P. Kelley (1985) Sunlight suppressing rejection of 280- to 320-nm UV-radiation-induced skin tumors in mice. J. Natl Cancer Inst. 74, 525-527.
9. Streilein, J. W., J. R. Taylor, V. Vincek, I. Kurimoto, T. Shimizu, C. Tie and C. Golomb (1994) Immune surveillance and sunlight-induced skin cancer. Immunol. Today 15, 174-179.
10. Hersey, P., G. Haran, E. Hasic and A. Edwards (1983) Alterations of T cell subsets and induction of suppressor T cell activity in normal subjects after exposure to sunlight. J. Immunol. 31, 171-174.
11. Frentz, G., F. da Cunha Bang, B. Munch-Petersen and G. L Wantzin (1988) Increased number of circulating suppressor T-lymphocytes in sun-induced multiple skin cancers. Cancer 61, 294-297.
12. Morison, W. L. (1989) Effects of ultraviolet radiation on the immune system in humans. Photochem. Photobiol. 50, 515-524.
13. Vermeer, M., G. J. Schmieder, T. Yoshikawa, J.-W. van den Berg, M. S. Metzman, R. Taylor and J. W. Streilein (1991) Effects of ultraviolet B light on cutaneous immune responses of humans with deeply pigmented skin. J. Invest. Dermatol. 97. 729-734.
14. Tseng, C., B. Hoffman, I. Kurimoto, T. Shimizu, G. J. Schmeider, J. R. Taylor and J. W. Streilein (1992) Analysis of effects of ultraviolet B radiation on induction of primary allergic reactions. J. Invest. Dermatol. 98, 871-875.
15. Madronich, S. and F. R. de Gruiji (1994) Stratospheric ozone depletion between 1979 and 1992: implications for biologically active ultraviolet-B radiation and non-melanoma skin cancer incidence. Photochem. Photobiol. 59, 541-546.
16. Ross, J. A., S. E. M. Howie, M. Narval, J. Maingay and T. J. Simpson (1986) Ultraviolet-irradiated urocanic acid suppresses delayed-type hypersensitivity to Herpes simplex virus in mice. J. Invest. Dermatol. 87, 630-633.
17. Noonan, F. P. and E. C. De Fabo (1992) Immunosuppression by ultraviolet B radiation: initiation by urocanic acid, Immunol. Today 13, 250-254.
18. Baden, H. P. and M. A. Pathak (1965) Urocanic acid in keratinizing tissue. Biochim. Biophys. Acta 104, 200-204.
19. Scott, I. R. (1981) Factors controlling the expressed activity of histidine ammonia-lyase in the epidermis and the resulting accumulation of urocanic acid. Biochem. J. 194, 829-838.
20. Reeve, V. E., G. E. Greenoak. P. J. Canfield, C. Boehm-Wilcox and C. H. Gallagher (1989) Topical urocanic acid enhances UV-induced tumour yield and malignancy in the hairless mouse. Photochem. Photobiol 49, 459-464.
21. Kurimoto, I. and J. W. Streilein (1992) cis-Urocanic acid suppression of contact hypersensitivity induction is mediated via tumor necrosis factor-α. J. lmmunol. 148, 3072-3078.
22. Applegate, L. E., R. D. Ley, J. Alcalay and M. L. Kripke (1989) Identification of the molecular target for the suppression of contact hypersensitivity by ultraviolet radiation. J. Exp. Med. 170, 1117-1131.
23. Kripke, M. L., P. A. Cox, L. G. Alas and D. B. Yarosh (1992) Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice Proc. Natl. Acad. Sci. USA 89, 7516-7520.
24. Van den Broeke, L. T. and G. M. J. Beyersbergen van Henegouwen (1993) UV-radiation protecting efficacy of thiols, studied with UVA-induced binding of 8-MOP and CPZ to rat epidermal biomacromolecules in vivo. Int. J. Radiat. Biol. 63, 493-500.
25. Van den Broeke, L. T. and G. M. J. Beyersbergen van Henegouwen (1994) UV radiation protecting efficacy of cysteine derivatives, studies with UVA-induced binding of 8-MOP and CPZ to rat epidermal biomacromolecules in vivo. Int. J. Radiat. Biol. 67, 411-420.
26. Van den Broeke, L. T. and G. M. J. Beyersbergen van Henegouwen (1995) Topically applied N-acetylcysteine as a protector against UVB-induced systemic immunosuppression. J. Photochem. Photobiol B Biol. 27, 61-65.
27. Morrison, H., D. Avnir and T. Zarrella (1980) Analysis of Z and E isomers of urocanic acid by high-performance liquid chromatography. J. Chromatogr. 183, 83-86.
28. Zwetsloot, J. C. M., A. P. Barbeiro, W. Vermeulen, H. M. Arthur, J. H. J. Hoeijmakers and C. Backendorf (1986) Microinjection of Escherichia coli UvrA, B, C and D proteins into fibroblasts of xeroderma pigmentosum complementation groups A and C does not result in restoration of UV-induced unscheduled DNA synthesis. Mutat. Res. 166, 89-98.
29. Friedberg, E. C. and D. A. Clayton (1972) Electron microscopic studies on substrate specificity of T4 excision repair endonuclease. Nature 237, 99-100
30. Kinuta, M., K. Yao, N Masuoka, J. Ohta, T. Teraoka and T. Ubuka (1991) Isolation and characterization of 3-[(carboxymethyl)thio]-3-(1H -imidazol-4-yl)propanoic acid from human urine and preparation of its proposed precursor, S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]cysteine. Biochem. J. 275, 617-621.
31. Kinuta, M., T. Ubuka, K. Yao, S. Futani, M. Fujiwara and Y. Kurozumi (1992) Isolation of S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]cysteine from human urine. Biochem. J. 283, 39-40.
32. Van den Broeke, L. T. and G. M. J. Beyersbergen van Henegouwen (1993) Thiols as potential UV radiation protectors: an in vitro study. J. Photochem. Photobiol. B Biol. 17, 279-286.
33. Van den Broeke, L. T., E. H. Ouijja, J. Bojarski and G. M. J. Beijerbergen van Henegouwen (1994) In vitro photodegradation of chlorpromazine. Photochem. Photobiol. 59, 140-144.
34. Fisher, G. J. and H. E. Johns (1976) Pyrimidine photodimers. In Photochemistry and Photobiology of Nucleic Acids. Vol. I. Chemistry (Edited by S. Y. Wang), pp. 225-294. Academic Press, London.
35. Van den Broeke, L. T. and G. M. J. Beijersbergen van Henegouwen (1994) The effect of N-acetylcysteine on the UVB-induced inhibition of epidermal DNA synthesis in rat skin. J. Photochem. Photobiol. B Biol. 26, 271-276.
36. Cruz, P. D. Jr. (1994) Ultraviolet B (UVB)-induced immunosuppression: biologic, cellular, and molecular effects. Adv. Dermatol. 9, 79-95.
37. 2 production and suppresses indirectly tumor necrosis factor-α levels. J. Immunol. 150, 4514-4523.
38. Peristeris, P., B. D. Clark, S. Gatti, R. Faggioni, A. Mantovani, M. Mengozzi, S. F. Orencole, M. Sironi and P. Ghezzi (1992) N-acetylcysteine and glutathion as inhibitors of tumor necrosis factor production. Cell. Immunol. 140, 390-399.
39. Senaldi, G., P. Pointaire, P.-F. Piguet and G. E. Grau (1994) Protective effect of N-acetylcysteine in hapten-induced irritant and contact hypersensitivity reactions. J. Invest. Dermatol. 102, 934-937.
40. 2 production by human keratinocytes: link to indomethacin-inhibitable UVB-induced immunosuppression. Photochem. Photobiol. 61, 303-309.
41. Miller, C. C., P. Hale and A. P. Pentland (1994) Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation. J. Btol. Chem. 269, 3529-3533.
42. Norval, M., J. W. Gilmour and T. J Simpson (1990) The effect of histamine receptor antagonists on immunosuppression induced by the cis-isomer of urocanic acid. Photodermatol. Photoimmunol. Photomed. 7, 243-248.
43. Norval, M., T. J. Simpson, E. Bardshiri and S. E. M. Howie (1989) Urocanic acid analogues and the suppression of the delayed type hypersensitivity response to Herpes simplex virus. Photochem. Photobiol. 49. 633-639.
44. Gilmour, J. W., M. Norval, T. J. Simpson, K. Neuvonen and P. Pasanen (1992/1993) The role of histamine-like receptors in immunosuppression of delayed hypersensitivity induced by cisurocanic acid. Photodermatol. Photoimmunol. Photomed. 9, 250-254.
45. Reeve, V. E., M. Bosnic, E. Rozinova and C. Boehm-Wilcox (1993) A garlic extract protects from ultraviolet B (280-320 nm) radiation-induced suppression of contact hypersensitivity. Photochem. Photobiol. 58, 813-817.