Effect of mexiletine on spinal cord injury dysesthetic pain

American Journal of Physical Medicine and Rehabilitation

Volumn 75, Issue 2, 1996, Pages 84-87

  Chiou Tan, Faye Y ^a   Tuel, Stephen M ^a   Johnson, Jane C ^b   Priebe, Michael M ^a   Hirsh, David D ^a   Strayer, Jonathan R ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b University of Missouri   (United States)

Author keywords

Drug; Pain; Spinal Cord Injury; Treatment

Indexed keywords

ANESTHETICS; DRUG THERAPY; IONS; NEUROLOGY; POTASSIUM; SODIUM; STATISTICAL METHODS;

BARTHEL FUNCTION; DIABETIC DYSESTHETIC NEUROPATHY; LIDOCAINE; MEDICATION; MEXILETINE; PAIN; SPINAL CORD INJURY;

PATIENT REHABILITATION;

IBUPROFEN; LIDOCAINE; MEXILETINE; PARACETAMOL; PLACEBO;

ADULT; ARTICLE; CHRONIC PAIN; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MECHANISM; DYSESTHESIA; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; INTRATHECAL DRUG ADMINISTRATION; MALE; MEDICAL RECORD; ORAL DRUG ADMINISTRATION; PAIN ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; SPINAL ANESTHESIA; SPINAL CORD INJURY;

ADULT; ANALGESICS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MEXILETINE; MIDDLE AGED; PAIN; PROSPECTIVE STUDIES; SPINAL CORD INJURIES; TREATMENT FAILURE;

EID: 0030110945     PISSN: 08949115     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002060-199603000-00002     Document Type: Article

References (15)

1. Staas WE, Formal CS, Gershkoff AM, et al.: Rehabilitation of the spinal cord-injured patient, in DeLisa J (ed): Rehabilitation Medicine, ed 1, chapter 32. Philadelphia, Lippincott, 1988, p 644.
2. Pollack LJ, Brown M, Boshes B, et al.: Pain below the level of injury of the spinal cord. Arch Neuro Psych 1951:65:319-322.
3. Davis L, Martin J: Studies upon spinal cord injuries: the nature and treatment of pain. J Neurosurg 1967:4:483-491.
4. Sweet WH: Phantom sensations following intraspinal injury. Neurochirurgia (Stuttg) 1975:18:139-154.
5. Guttman L: Spinal Cord Injuries - Comprehensive Management and Research, ed 2. Oxford, Blackwell Scientific, 1976, pp 280-294.
6. Burke DC, Woodward JM: Pain and phantom sensations in spinal paralysis, in Vinken PJ, Bruyn GW (ed): Handbook of Clinical Neurology. Amsterdam, North Holland, 1976, pp 489-499.
7. Donovan WH, Dimitrijevic MR, Dahm L, et al.: Neurophysiological approaches to chronic pain following spinal cord injury. Paraplegia 1982;20:135-146.
8. Loubser PG, Donovan WH: Diagnostic spinal anaesthesia in chronic spinal cord injury pain. Paraplegia 1991:29:25-36.
9. Tanelian DL, MacIver MB: Analge sic concentrations of lidocaine suppress tonic A-delta and C fiber discharges produced by acute injury. Anesthesiology 1991:74:934-936.
10. Dejard A, Petersen P, Kastrup J: Mexiletine for treatment of chronic painful diabetic neuropathy. Lancet 1988;Jan 2(9):9-11.
11. Tanelian DL, Brose WG: Neuropathic pain can be relieved by drugs that are use-dependent sodium channel blockers: lidocaine, carbamazepine, and mexiletine. Anesthesiology 1991:74: 949-951.
12. Stracke H, Meyer UE, Schumacher HE, et al.: Mexiletine in the treatment of diabetic neuropathy. Diabetes Care 1992:15: 1550-1554.
13. Lindstrom P, Lindblom U: The analgesic effect of tocainide in trigeminal neuralgia. Pain 1987:28:45-50.
14. Physicians' Desk Reference, ed. 47. Montvale, NJ, Medical Economics Data, 1993, pp 707-710.
15. Lathers CM, O'Rourke DK: Antiarrhythmic agents, in Smith CM, Reynard AM (ed): Textbook of Pharmacology, Philadelphia, WB Saunders, ed 1. 1992, p 539.