Seeing double: Crystal structures of the type I TNF receptor

Journal of Molecular Recognition

Volumn 9, Issue 2, 1996, Pages 113-117

  Naismith, James H ^a   Brandhuber, Barbara J ^a   Devine, Tracey Q ^b   Sprang, Stephen R ^c  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b AMGEN INC   (United States)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOTOXIN; TUMOR NECROSIS FACTOR RECEPTOR;

BINDING SITE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CONFERENCE PAPER; ENDOSOME; METABOLISM; PH; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; ENDOSOMES; HYDROGEN-ION CONCENTRATION; LYMPHOTOXIN-ALPHA; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECEPTORS, TUMOR NECROSIS FACTOR;

EID: 0030110938     PISSN: 09523499     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1352(199603)9:2<113::AID-JMR253>3.0.CO;2-H     Document Type: Conference Paper

References (26)

1. Banner, D. W., D'Arcy, A., James, W., Gentz, R., Schoenfeld, H.-J., Broger, C., Loetscher, H. and Lesslauer, W. (1993). Crystal structure of the soluble human 55 kd TNF receptor-human TNF-β complex: Implications for TNF receptor activation. Cell 73, 431-445.
2. Bajzer, Z., Myers, A. C. and Vuk-Pavlovic, S. (1989). Binding internalization and intracellular processing. J. Biol. Chem. 264, 13623-13631.
3. Balkwill, F. (1993). Cyokines in health and disease. Immunology Today 14, 149-150.
4. Bazan, J. F. (1993). Emerging families of cytokines and receptors. Current Biology 3, 603-606.
5. Bazzoni, F., Alejos, E. and Beutler, B. (1995). Proc. Natl. Acad. Sci., USA., in press.
6. Bernstein, F. C., Koetzle, T. F., Williams, J. B., Meyer, E. F., Jr., Brice, M. D., Rodgers, J. R., Kennard, O., Shimanouchi, T. and Tasumi, M. (1977). The protein databank: A computer-based archival file for macromolecular structure. J. Mopl. Biol. 112, 535-542.
7. Beutler, B. (1992). The tumor necrosis factors: the molecules and their emerging roles in medicine. Raven Press, New York.
8. Beutler, B. and Cerami, A. (1988). Tumor necrosis, cachexia, shock, and inflammation: A common mediator. Ann. Rev. Biochem. 57, 505-518.
9. Boldin,. M. P., Mett, I. L., Varfolomeev, E. E., Chumakov, I., Sheme-Avni, Y., Camonis, J. H. and Wallach, D.(1995). Self-association of the 'death domains' of the p55 tumor necrosis factor (TNF) receptor and Fas.APO1 prompts signalling for TNF and Fas/APO1 effects. J. Biol. Chem., 270, 387-391.
10. Brakebrush, C., Nophar, Y., Kemper, Y., Engelmann, H. and Wallach, D. (1992). Cytoplasmic truncation of the p55 tumour necrosis (TNF) receptor abolishes signalling, but not induced shedding of receptor. EMBO J. 11, 943-950.
11. Brockhaus, M., Schoenfeld, H.-J., Schlaeger, E.-J., Hunziker, W., Lesslauer, W., and Loetscher, H. (1990). Identification of 2 types of tumor-necrosis-factor receptors on human cell-lines by menoclonal-antibodies. Proc. Natl. Acad. Sci. USA 87, 3127-3131.
12. Brünger, A. T. (X-PLOR) (Version 2.1) Manual, Yale University, New Haven.
13. CCP4 (1994). The CCP4 Suite: programs for protein crystallography. Acta Cryst. D50, 760-763.
14. Engelman, H., Holtmann, H., Brakebusch, C., Avni, Y. S., Sarovm I., Nophar, Y., Hadas, E., Leitner, O., and Wallach, D. (1990a). J. Biol. Chem. 265, 14497-14504.
15. Engelmann, H., Novick, D. and Wallach, D. (1990b). Two tumor necrosis factor-binding proteins purified from human urine. J. Biol. Chem., 265, 1531-1536.
16. Engh, R. A. and Huber, R. (1991). Accurate bond and angle parameters for X-ray protein-structure refinement. Acta Cryst. A47, 392-400.
17. Grazioli, L., Casero, D., Restivo, A., Cozzi, E. and Maruci, F. (1994). Tumor necrosis factor-driven formation of disulphide-linked receptor aggregates. J. Biol. Chem. 269, 22304-22309.
18. Helson, L., Green, S., Carswell, E. and Old, L. J. (1975). Effect of tumor necrosis factor on cultured human melanoma cells. Nature 258, 731-732.
19. Jones, T. A. & Kjeldgaard, M. (1990). O Version 5.6, Department of Molecular Biology, Uppsala University, Sweden unpublished.
20. Lawrence, M. C. and Colman, P. M. (1993). Shape complimentarity at protein/protein interfaces. J. Mol. Biol. 234, 946-950.
21. Lee, B. and Richards, F. M. (1971). The interpretation of protein structure: estimation of static accessibility. J. Mol. Biol. 55, 379-400.
22. Naismith, J. H., Devine, T. O., Brandhuber, B. J. and Sprang, S. R. (1995). Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor. J. Biol. Chem., 270, 13303-13307.
23. Rodseth, L. E., Brandhuber, B., Devine, T. Q., Eck, M. J., Hale, K., Naismith, J. H. and Sprang, S. R. (1994) Two crystal forms of the type I tumor necrosis factor receptor. J. Mol. Biol. 239, 332-335.
24. Song, H. Y., Dunbar, J. D. and Donner, D. B. (1994). Aggregation of the intracellular domain of the type 1 tumor necrosis factor receptor defined by the two-hybrid system. J. Biol. Chem. 269, 22492-22495.
25. Van Ostade, X., Vandenabeele, P., Everadt, B., Loetscher, H., Gentz, R., Brockhaus, M., Lesslauer, W., Tavernier, J., Broukaert, P. and Fiers, W. (1993). Human TNF mutants with selective activity on the p55 receptor. Nature, 361, 266-269.
26. Vuk-Pavlovic, S. and Kovach, J. S. (1989). Recycling of tumor necrosis factor-alpha-receptor in MCF-7 cells. FASEB J. 3, 2633-2640.