Experimental Evaluation of Designs for the Simulated Countercurrent Moving Bed Separator

AIChE Journal

Volumn 42, Issue 3, 1996, Pages 683-690

  Tonkovich, Anna Lee Y ^a,b   Carr, Robert W ^a  

^a University of Minnesota   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADSORPTION; BINARY MIXTURES; COMPUTER SIMULATION; ETHERS; FLOW OF FLUIDS; PROPYLENE; SEPARATION; SEPARATORS;

ADSORBENT BEDS; CHROMOSORB; COUNTERCURRENT MOVING BED SEPARATOR; FEED SWITCHING CYCLE; MAXIMUM PRODUCT CONCENTRATION;

COLUMN CHROMATOGRAPHY;

EID: 0030109695     PISSN: 00011541     EISSN: None     Source Type: Journal    
DOI: 10.1002/aic.690420309     Document Type: Article

References (43)

1. Barker, P. E., "Configuration Chromatographic Refining," Progress in Separation and Purification, Chap. 10, Wiley-Interscience, New York, p. 325 (1971).
2. Barker, P. E., and D. Critcher, "The Separation of Volatile Liquid Mixtures by Continuous Gas-Liquid Chromatography," Chem. Eng. Sci., 13(2), 82 (1960).
3. Barker, P. E., and R. Deeble, "Production Scale Organic Mixture Separation Using a New Sequential Chromatographic Machine," Anal. Chem., 45(7), 1121 (1973).
4. Barker, P. E., F. Ellison, and B. Hatt, "A New Process for the Continuous Fractionation of Dextran," Ind. Eng. Chem. Process Des. Develop., 17(3), 302 (1978).
5. Barker, P. E., K. England, and G. Vlachogiannis, "Mathematical Model for the Fractionation of Dextran on a Semi-Continuous Countercurrent Simulated Moving Bed Chromatograph," Chem. Eng. Res. Dev., 61, 241 (1983).
6. Barker, P. E., and E. Abusabah, "The Separation of Synthetic Mixtures of Glucose and Fructose and Also Inverted Sucrose Feedstocks Using Countercurrent Chromatographic Techniques," Chromatographia, 20(1), 9 (1985).
7. Barker, P. E., A. Knoechelmann, and G. Ganetsos, "Simulated Counter-Current Moving Column Chromatography Use in the Continuous Separation of Carbohydrate Mixtures," Chromatographia, 29(3-4), 161 (1990).
8. Broughton, D. B., "Molex: Case History of a Process," Chem. Eng. Prog., 64(8), 60 (1968).
9. Broughton, D. B., R. Neuzil, J. Pharls, and C. Brearly, "The Parex Process for Recovering Paraxylene," Chem. Eng. Prog., 66(9), 70 (1970).
10. Broughton, D. B., "Production-Scale Adsorptive Separations of Liquid Mixtures by Simulated Moving-Bed Technology," Sep. Sci. Technol., 19(11-12), 723 (1984).
11. Ching, C. B., and D. Ruthven, "An Experimental Study of a Simulated Countercurrent Adsorption System: I. Isothermal Steady-State Operation," Chem. Eng. Sci., 40(6), 877 (1985a).
12. Ching, C. B., and D. Ruthven, "An Experimental Study of a Simulated Countercurrent Adsorption System: II. Transient Response," Chem. Eng. Sci., 40(6), 887 (1985b).
13. Ching, C. B., D. Ruthven, and K. Hidajat, "An Experimental Study of a Simulated Countercurrent Adsorption System: III. Sorbex Operation," Chem. Eng. Sci., 40(8), 1411 (1985c).
14. Ching, C. B., and D. Ruthven, "An Experimental Study of a Simulated Countercurrent Adsorption System. IV. Nonisothermal Operation," Chem. Eng. Sci., 41(12), 3063 (1986).
15. Ching, C. B., C. Ho, K. Hidajat, and D. M. Ruthven, "An Experimental Study of a Simulated Countercurrent Adsorption System. V. Comparison of Resin and Zeolite Adsorbents for Fructose-Glucose Separation at High Concentration," Chem. Eng. Sci., 42(11), 2547 (1987).
16. Ching, C., C. Ho, and D. M. Ruthven, "Experimental Study of a Simulated Countercurrent Adsorption System," Chem. Eng. Sci., 43(3), 703 (1988).
17. Ching, C. B., K. Chu, K. Hidajat, and M. Uddin, "Experimental and Modeling Studies on the Transient Behavior of a Simulated Countercurrent Adsorber," J. Chem. Eng. Japan, 24(5), 614 (1991).
18. De Rosset, A., R. Neuzil, and D. B. Broughton, "Industrial Applications of Preparative Chromatography," Percolation Processes, 249 (1981).
19. Fish, B., R. W. Can, and R. Aris, "Computer-Aided Experimentation in Countercurrent Reaction Chromatography and Simulated Countercurrent Chromatography," Chem. Eng. Sci., 43, 1867 (1988).
20. Fish, B., R. W. Carr, and R. Aris, "Design and Performance of a Simulated Countercurrent Moving-Bed Separator," AIChE J., 39(11), 1783 (1993).
21. Freund, M., P. Benedek, and L. Szepesy, "Chemical Engineering Design of a Unit for Continuous Gas Chromatography (Hypersorption)," in Vapor Phase Chromatography, Butterworth, London (1957).
22. Ha, H., K. Row, and W. Lee, "A Plate Model for Moving Feed Injection Chromatography: I. Simulation Results," Sep. Sci. Technol., 22(1), 141 (1987a).
23. Ha, H., K. Row, and W. Lee, "A Plate Model for Moving Feed Injection Chromatography: II. Experimental Results," Sep. Sci. Technol., 22(4), 1281 (1987b).
24. Hashimoto, K., S. Adachi, H. Noujima, and H. Maruyama, "Models for the Separation of Glucose/Fructose Mixtures Using a Simulated Moving-Bed Adsorber," J. Chem. Eng. Japan, 16(5), 400 (1983a).
25. Hashimoto, K., S. Adachi, H. Noujima, and Y. Ueda, "A New Process Combining Adsorption and Enzyme Reaction for Producing Higher-Fructose Syrup," Biotech. Bioeng., XXV, 2371 (1983b).
26. Hashimoto, K., M. Yamada, Y. Shirai, and S. Adachi, "Continuous Separation of Glucose-Salts Mixtures with Nonlinear and Linear Adsorption Isotherms by Using a Simulated Moving Bed Adsorber," J. Chem. Eng. Japan, 20(4), 405 (1987).
27. Hashimoto, K., M. Yamada, S. Adachi, and Y. Shirai, "A Simulated Moving-Bed Adsorber with Three Zones for Continuous Separation of L-Phenylalanine and NaCl," J. Chem. Eng. Japan, 22(4), 432 (1989).
28. Hashimoto, K., Y. Shirai, M. Morishita, and S. Adachi, "A Simplified Design Method for a Simulated Moving-Bed Adsorber," Kag. Kog. Ron., 16, 193 (1990a).
29. Hashimoto, K., Y. Shirai, S. Adachi, and M. Horie, "Comparison of Efficiency in Separation of Maltose and Glucose between Conventional Batch Chromatography and Simulated Moving-Bed Adsorber," Kag. Kog. Ron., 17, 623 (1990b).
30. Hidajat, K., C. Ching, and D. M. Ruthven, "Numerical Simulation of a Semi-Continuous Countercurrent Adsorption Unit for Fructose-Glucose Separation," Chem. Eng. J., 33, B55 (1986).
31. Huang, S., C. Lin, W. Chang, and W. Lee, "Enzyme Purification and Concentration by Simulated Moving Bed Chromatography: An Experimental Study," Chem. Eng. Commun., 45, 291 (1986).
32. Kishihara, S., H. Horikawa, H. Tamaki, S. Fujii, Y. Nakajima, and K. Nishio, "Continuous Chromatographic Separation of Palatinose and Trehalulose Using a Simulated Moving-Bed Adsorber," J. Chem. Eng. Japan, 22(4), 434 (1989).
33. Kubota, K., C. Hata, and S. Hayashi, "A Study of a Simulated Moving Bed Adsorber Based on the Axial Dispersion Model," Can. J. Chem. Eng., 67, 1025 (1989).
34. Maki, H., H. Fukuda, and H. Morikawa, "The Separation of Glutathione and Glutamic Acid Using a Simulated Moving-Bed Adsorber System," J. Fermentation Technol., 65(1), 61 (1987).
35. McGary, R., and P. Wankat, "Improved Preparative Liquid Chromatography: The Moving Feed Point Method," Ind. Eng. Chem. Fundam., 22(1), 10 (1983).
36. Ruthven, D. M., "Adsorption Separation Processes," in Principles of Adsorption and Adsorption Processes, Chap. 12, Wiley-Interscience, New York, p. 380 (1984).
37. Ruthven, D. M., and C. B. Ching, "Counter-Current and Simulated Counter-Current Adsorption Separation Processes," Chem. Eng. Sci., 44(5), 1011 (1989).
38. Saska, M., M. Wu, S. Clarke, and K. Iqbal, "Continuous Separation of Sugarcane Molasses with a Simulated Moving-Bed Adsorber. Adsorption Equilibria, Kinetics and Application," Sep. Sci. Technol., 27(13), 1711 (1992).
39. Storti, G., M. Mazzotti, L. Furlan, M. Morbidelli, and S. Carra, "Performance of a Six-Port Simulated Moving-Bed Pilot Plant for Vapor-Phase Adsorption Separations," Sep. Sci. Technol., 27(14), 1889 (1992).
40. Szepesy, L., A. Sebestyen, I, Feher, and Z. Nagy, "Continuous Liquid Chromatography," J. Chrom., 108, 285 (1975).
41. Wankat, P., "Improved Efficiency in Preparative Chromatographic Columns Using a Moving Feed," Ind. Eng. Chem. Fundam., 16(4), 468 (1977).
42. Wankat, P., "New Adsorption Methods," Chem. Eng. Ed., XVIII, 20 (1984).
43. Wankat, P., and P. Ortiz, "Moving Feed Point Gel Permeation Chromatography, An Improved Preparative Technique," Ind. Eng. Chem. Proc. Des. Dev., 21(3), 416 (1982).