In situ hybridization of stromelysin mRNA in the synovial biopsies from rheumatoid arthritis

Tohoku Journal of Experimental Medicine

Volumn 178, Issue 3, 1996, Pages 315-330

  Sawai, Takashi ^a,b   Uzuki, Miwa ^a   Harris Jr , Edward D ^c   Kurkinnen, Markku ^b   Trelstad, Robert L ^b   Hayashi, Masando ^b  

^a TOHOKU UNIVERSITY HOSPITAL   (Japan)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Immunohistochemistry; In situ hybridization; Rheumatoid arthritis; Stromelysin

Indexed keywords

MESSENGER RNA; METALLOPROTEINASE; STROMELYSIN;

ADULT; AGED; ARTICLE; BIOSYNTHESIS; CELL NUCLEUS; CYTOLOGY; ELECTRON MICROSCOPY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KARYOMETRY; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; ULTRASTRUCTURE;

ADULT; AGED; ARTHRITIS, RHEUMATOID; CELL NUCLEUS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KARYOMETRY; MALE; MATRIX METALLOPROTEINASE 3; METALLOENDOPEPTIDASES; MICROSCOPY, ELECTRON; MIDDLE AGED; RNA, MESSENGER; SYNOVIAL FLUID;

EID: 0030100223     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.178.315     Document Type: Article

References (45)

1. Aggeler, J., Frisch, S.M. & Werb, Z. (1984) Collagenase is a major gene product of induced rabbit synovial fibroblast. J. Cell Biol., 98, 1656-1661.
2. Arnett, F.C., Edworthy, S.M., Bloch, D.A., McShane, D.J., Fries, J.F., Cooper, N.S., Healey, L.A., Kaplan, S.R., Liang, M.H., Luthra, H.S., Medsger, T.A., Jr., Mitchell, D.M., Neustadt, D.H., Pinals, R.S., Schaller, J.G., Sharp, J.T., Wilder, R.L. & Hunder, G.C. (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatic arthritis. Arthritis Rheum., 31, 315-324.
3. 2-microglobulin-like proteins. Science, 243, 655-657.
4. Case, J.P., Sano, H., Lafyatis, R., Remmers, E.F., Kumkumian, G.K. & Wilder, R.L. (1989) Transin/stromelysin expression in the synovium of rats with experimental erosive arthritis. J. Clin. Invest., 84, 1731-1740.
5. Cawston, T.E., Mercer, E., Silva, M.D. & Hazleman, B.L. (1984) Metalloproteinase and collagenase inhibitor in rheumatoid synovial fluid. Arthritis Rheum., 27, 285-290.
6. Dalton, B.J., Connor, J.R. & Johnson, W.J. (1989) Interleukin-1 induces interleukin 1-alpha and Interleukin-1 beta gene expression in synovial fibroblast and peripheral blood monocytes. Arthritis Rheum., 32, 279-287.
7. Dayer, J.M., Beutler, B. & Cerami, A. (1985) Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblast. J. Exp. Med., 162, 2163-2168.
8. Dunchan, M.R. & Berman, B. (1989) Differential regulation of collagen, glycosamino-glycan, fibronectin, and collagenase activity production in cultured human adult dermal fibroblasts by interleukin 1-alpha and beta and tumor necrosis factor-alpha and beta. J. Invest. Dermatol., 92, 699-706.
9. Fell, H.B. (1978) Synoviocyte. J. Clin. Pathol., 31, Suppl., 14-24.
10. Frisch, S.M., Clark, E.J. & Werb, Z. (1987) Coordinate regulation of stromelysin and collagenase genes determined with cDNA probes: Cycloheximide inhibition/macrophage/capillary endothelial cells/phorbol esters/metalloproteinases. Proc. Natl. Acad. Sci. USA, 84, 2600-2604.
11. Galloway, W.A., Murphy, G., Sandy, J.D., Gavrilovic, J., Cawaton, T.E. & Reynolds, J.J. (1983) Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components. Biochem. J., 209, 741-752.
12. Gavrilovic, J., Hembry, R.M., Reynolds, J.J. & Murphy, G. (1987) Tissue inhibitor of metalloproteinase (TIMP) regulates extracellular type II collagen degradation by chondrocyte and endothelial cells. J. Cell Sci., 87, 357-362.
13. Graabaek, P.M. (1984) Characteristics of the two types of synoviocytes in rat synovial membrane: An ultrastructural study. Lab. Invest., 50, 690-702.
14. Harris, E.D., Jr. (1985) Pathogenesis of rheumatoid arthritis. In: Textbook of Rheumatology. 2nd ed. edited by W.N. Kelly, E.D. Harris, Jr., S. Ruddy & C.B. Sledge, WB Saunders Co., Philadelphia, PA, pp. 816-915.
15. Harris, E.D., Jr., Welgus, H.G. & Krane, S.M. (1984) Regulation of the mammalian collagenase. Collagen Rel. Res., 4, 493-512.
16. Hayashi, M., Ninomiya, Y., Parsons, J., Hayashi, K., Olsen, B.R. &, Trelstad, R.L. (1986) Differential localization of mRNA of collagen types I and II in chick fibroblasts, chondrocytes, and corneal cells by in situ hybridization using cDNA probes. J. Cell Biol., 102, 2302-2309.
17. Hopkins, S.J., Humphreys, M. & Jayson, M.I.V. (1988) Cytokines in fluid. 1. The presence of biologically active and immunoreactive IL-1. Clin. Exp. Immunol., 72, 422-427.
18. Howat, D.W., Glynn, L.E., Bitensky, L. & Chayen, J. (1987) The origin of the apparent synovial lining cell hyperplasia in rheumatoid arthritis: Evidence for a deep stem cell. J. Exp. Pathol., 68, 259-266.
19. Hoyhtya, M., Turpeenniemi-Hujanen, T., Stetler-Stevenson, W., Krutzsch, H., Tryggvason, K. & Liotta, L.A. (1988) Monoclonal antibodies to type IV collagenase recognize a protein with limited sequence homology to interstitial collagenase and stromelysin. FEBS Lett., 233, 109-113.
20. Krane, S.M. (1982) Collagenase and collagen degradation. J. Invest. Dermatol., Suppl., 79, 83s-86s.
21. Kumkumian, G.K., Lafyatis, R., Remmers, E.F., Case, J.P., Kim, S.J. & Wilder, R.L. (1989) Platelet-derived growth factor and IL-1 interactions in rheumatoid arthritis. Regulation of synoviocyte proliferation, prostaglandin production and collagenase transcription. J. Immunol., 143, 833-837.
22. Linck, G. & Porte, A. (1981) Cytophysiology of the synovial membrane: Distinction of two cell types of the intima revealed by their reaction with horseradish peroxides and iron saccharate in the mouse. Biol. Cell, 42, 147-152.
23. Liotta, L.A., Rao, C.N. & Barsky, S. (1983) Tumor invasion and the extracellular matrix. Lab. Invest., 49, 636-649.
24. Mapp, P.I. & Revell, P.A. (1988) Ultrastructural characterization of macrophage (type A cells) in the synovial lining. Rheumatol. Int., 8, 171-176.
25. Matrisian, L.M., Leroy, P., Ruhlmann, C., Gensel, M.C. & Breathnach, R. (1986a) Isolation of the oncogene and epidermal growth factor-induced transin gene: Complex control in rat fibroblast. Molecular cellular Biol., 6, 1679-1686.
26. Matrisian, L.M., Boeden, G.T., Krieg, P., Furstenberger, G., Briand, J-P., Leroy, P. & Breathnach, R. (1986b) The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc. Natl. Acad. Sci. USA, 83, 9413-9417.
27. Miyasaka, N., Sato, K., Goto, M., Sasano, M., Natsuyama, M., Inoue, K. & Nishioka, K. (1988) Augmented interleukin-1 production and HLA-DR expression in the synovium of rheumatoid arthritis patients: Possible involvement in joint destruction. Arthritis Rheum., 31, 480-486.
28. Murphy, G., McAlpine, C.G., Poll, C.T. & Reynolds, J.J. (1985) Purification and characterization of a bone metallopioteinase that degrades gelatin and type IV and V collagen. Biochem. Biophys. Acta, 83, 49-58.
29. Murphy, G., Hembry, R.M. & Reynolds, J.J. (1986) Characterization of a specific antiserum to rabbit stromelysin and demonstration of the synthesis of collagenase and stromelysin by stimulated rabbit articular chondrocyte. Coll. Relat. Res., 6, 351-364.
30. Murphy, G., Cockett, M.I., Stephens, P.E., Smith, B.J. & Docherty, A.J.P. (1987) Stromelysin is a proactivator of procollagenase. A study with natural and recombinant enzymes. Biochem. J., 248, 265-268.
31. Murphy, G., Nagase, H. & Brinckerhoff, C. (1988) Relationship of procollagenase activator, stromelysin and matrix metalloproteinase 3. Collagen Rel. Res., 8, 389-391.
32. Okada, Y., Nagase, H. & Harris, E.D., Jr. (1987) Matrix metalloproteinases 1, 2, and 3 from rheumatoid synovial cells are sufficient to destroy joints. J. Rheumatol., Suppl. 4, 14, 41-42.
33. Okada, Y., Konomi, Y., Yada, T., Kimata, K. & Nagase, H. (1989a) Degradation of type IX collagen by matrix metalloproteinase 3 (stromelysin) from human rheumatoid synovial cells. FEBS Lett., 244, 473-476.
34. Okada, Y., Takeuchi, N., Tomita, K., Nakanishi, I. & Nagase, H. (1989b) Immunolocalization of matrix metalloproteinase 3 (stromelysin) in rheumatoid synovioblasts (B cell): Correlation with rheumatoid arthritis. Ann. Rheum. Dis., 48, 645-653.
35. Quinones, S., Saus, J., Ohtani, Y., Harris, E.D., Jr. & Kurkinnen, M. (1989) Transcriptional regulation of human stromelysin. J. Biol. Chem., 264, 8339-8344.
36. Rooney, M., Condell, D., Quinlan, W., Daly, L., Whelan, A., Feighery, C. & Bresnihan, B. (1988) Analysis of the histologic variation of synovitis in rheumatoid arthritis. Arthritis Rheum., 31, 956-963.
37. Saus, J., Quinones, S., Ohtani, Y., Nagase, H., Harris, E.D., Jr. & Kurkinnen, M. (1988) The complete primary structure of human matrix metalloproteinase-3. J. Biol. Chem., 263, 6742-6745.
38. Scharffetter, K., Heckermann, M., Hatamochi, A., Mauch, C., Stein, B., Riethmuller, G., Ziegler-Heitbrock, H.W. & Krieg, T. (1989) Synergistic effect of tumor necrosis factor-alpha and interferon-gamma on collagen synthesis of human skin fibroblasts in vivo. Exp. Cell Res., 181, 409-411.
39. Schmidt, T.M., Maynes, R., Jeffrey, J.J. & Linsenmayer, T.F. (1986) Type X collagen contains two cleavage sites for a vertebrate collagenase. J. Biol. Chem., 261, 4184-4189.
40. Steinbrocker, O., Traeger, C.H. & Batterman, R.C. (1949) Therapeutic criteria in rheumatoid arthritis. JAMA, 149, 659-662.
41. Tezuka, F. & Sawai, T. (1983) Hyperplasia of small hepatic cells in the precancerous condition of cirrhotic livers. Tohoku, J. Exp. Med., 139, 171-178.
42. Unemori, E.N. & Werb, Z. (1962) Reorganization of polymerized actin: A possible trigger for induction of procollagenase in fibroblast culture in and on collagen gels. J. Cell Biol., 103, 1021-1031.
43. Werb, Z., Hembry, R.M., Murphy, G. & Aggeler, J. (1987) Commitment to expression of the metalloendopeptidases, collagenase and stromelysin: Relationship of inducing events to changes in cytoskeletal architecture. J. Cell Biol., 102, 1656-1661.
44. Whitham, S.E., Murphy, G., Angel, P., Rahmsdorf, H.J., Smith, B.J., Lyons, B.J., Harris, T., Jr., Reynolds, J.J., Herrilich, P. & Docherty, A.J.P. (1986) Comparison of human stromelysin and collagenase by cloning and sequence analysis. Biochem. J., 240, 913-916.
45. Wooley, D.E., Crossley, M.J. & Evason, J.M. (1977) Collagenase at sites of cartilage erosion in the rheumatoid joint. Arthritis Rheum., 20, 1231-1239.