The use of a reversible transcription inhibitor, DRB, to investigate the involvement of specific proteins in the ocular circadian system of Aplysia

Journal of Biological Rhythms

Volumn 11, Issue 1, 1996, Pages 45-56

  Koumenis, Constantinos ^a,b   Tran, Quang ^a   Eskin, Arnold ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aplysia; Circadian rhythms; Protein synthesis; Transcriptor

Indexed keywords

APLYSIA; APLYSIA CALIFORNICA;

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; LEUCINE; NERVE PROTEIN; URIDINE;

ANIMAL; APLYSIA; ARTICLE; AUTORADIOGRAPHY; BIOSYNTHESIS; CIRCADIAN RHYTHM; DRUG EFFECT; EYE; GENETIC TRANSCRIPTION; KINETICS; METABOLISM; OPTIC NERVE; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; VISUAL SYSTEM FUNCTION;

ANIMALS; APLYSIA; AUTORADIOGRAPHY; CIRCADIAN RHYTHM; DICHLORORIBOFURANOSYLBENZIMIDAZOLE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EYE; KINETICS; LEUCINE; NERVE TISSUE PROTEINS; OCULAR PHYSIOLOGY; OPTIC NERVE; TRANSCRIPTION, GENETIC; URIDINE;

EID: 0030098250     PISSN: 07487304     EISSN: None     Source Type: Journal    
DOI: 10.1177/074873049601100105     Document Type: Article

References (32)

1. Aronson BD, Johnson KA, Loros JJ, and Dunlap J (1994) Negative feedback defining a circadian clock: Autoregulation of the clock gene frequency. Science 263:1578-1584.
2. Benz R (1985) Porins from bacterial and mitochondrial outer membranes. CRC Crit Rev Biochem 19:145-190.
3. Colombini M (1979) A candidate for the permeability pathway of the outer mitochondrial membrane. Nature 279:643-645.
4. Dermietzel R, Hwang T-K, Buettner R, Hofer A, Dotzler E, Kremer M, Deutzmann R, Thinnes FP, Fishman GI, Spray DC, and Siemen D (1994) Cloning and in situ localization of a brain-derived porin that constitutes a large-conductance anion channel in astrocytic plasma membranes. Proc Natl Acad Sci U S A 91:499-503.
5. Dunlap JC (1993) Genetic analysis of circadian clocks. Annu Rev Physiol 55:683-728.
6. Edmunds LN (1988) Cellular and Molecular Bases of Biological Clocks, Springer Verlag, New York.
7. Eskin A, Yeung SJ, and Klass MR (1984) Requirement for protein synthesis in the regulation of a circadian oscillator by serotonin. Proc Natl Acad Sci U S A. 81:7637-7641.
8. Hardin PE, Hall JC, and Rosbash M (1990) Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels. Nature 343:536-540.
9. Hölltä E, Sistonen L, and Alitalo K (1988) The mechanisms of ornithine decarboxylase deregulation in c-Ha-ras oncogene-transformed NIH 3T3 cells. J Biol Chem 263:4500-4507.
10. Jacklet JW (1980) Circadian rhythm from the eye of Aplysia: Temperature compensation of the effects of protein synthesis inhibitors. J Exp Biol 84:1-15.
11. Karakasian MW and Hastings JW (1962) The inhibition of a biological clock by Actinomycin D. Proc Natl Acad Sci U S A 48:2130-2137.
12. Khalsa SBS, Whitmore D, and Block GD (1992) Stopping the circadian pacemaker with inhibitors of protein synthesis. Proc Natl Acad Sci U S A 89:10862-10866.
13. Killewich L, Schutz G, and Feigelson P (1975) Functional level of rat liver tryptophan 2,3-dioxygenase messenger RNA during superinduction of enzyme with actinomycin D. Proc Natl Acad Sci U S A 72:4285-4287.
14. Koumenis C and Eskin A (1992) The hunt for mechanisms of circadian timing in the eye of Aplysia. Chronobiol Int 3:201-221.
15. Koumenis C, Nunez-Regueiro M, Raju U, Cook R, and Eskin A (1995) Identification of three proteins in the eye of Aplysia whose synthesis is altered by serotonin (5-HT). J Biol Chem 270:14619-14627.
16. McEnery MW, Snowman AM, Trifilleti RR, and Snyder S (1992) Isolation of the mitochondrial benzodiazepine receptor: Association with the voltage-dependent anion channel and the adenine nucleotide carrier. Proc Natl Acad Sci U S A 89:3170-3174.
17. Moore-Ede MC, Sulzman FM, Fuller CA (1982) The docks that time us. Physiology of the Circadian timing system, Harvard University Press, Cambridge, MA.
18. Ohi K and Takahashi JS (1991) Effects of the transcriptional inhibitor 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) on the circadian melatonin rhythm of cultured chick pineal cells. Soc Neurosci Abstr 17:675.
19. Palmiter RD and Schimke RT (1973) Regulation of protein synthesis in chick oviduct: III. Mechanism of ovalbumin "superinduction" by actinomycin D. J Biol Chem 248:1502-1512.
20. Pittendrigh CS (1976) Circadian Clocks: What are they? In The Molecular Basis of Circadian Rhythms, JW Hastings and HG Schweiger, eds, pp 11-48, Abakon Verlagsgesellschaft, Berlin.
21. Pittendrigh CS and Daan S (1976) A functional analysis of circadian pacemakers in nocturnal rodents: IV. Entrainment: Pacemaker as clock. J Comp Physiol 106:291-331.
22. Raju U, Koumenis C, Nunez-Regueiro M, and Eskin A (1991) Alteration of the phase and period of a circadian oscillator by a reversible transcription inhibitor. Science 253:673-675.
23. Raju U, Yeung SJ, and Eskin A (1990) Involvement of proteins in light resetting ocular circadian oscillators in Aplysia. Am J Physiol 258:R256-R262.
24. Rosbash M and Hall JC (1989) The molecular biology of circadian rhythms. Neuron 3:387-398.
25. Rothman BS and Strumwasser F (1976) Phase-shifting the circadian rhythm of neuronal activity in the isolated Aplysia eye with puromycin and cycloheximide. J Gen Physiol 68:359-384.
26. Rothman BS and Strumwasser F (1977) Manipulation of a neuronal circadian oscillator with inhibitors of macromolecular synthesis. Fed Proc 36:2050-2055.
27. Tamm I and Sehgal PB (1978) Halobenzimidazole ribosides and RNA synthesis of cells and viruses. Adv Virus Res 22:187-258.
28. Thinnes FP, Götz H, Kayser H, Benz R, Schmidt WE, Kratzin HD, and Hilschmann N (1989) Identification of human porins: I. Purification of a porin from human B-lymphocytes (Porin 31HL) and the topochemical proof of its expression on the plasmalemma of the progenitor cell. Biol Chem Hoppe Seyler 370:1253-1264.
29. Wallon UM, Persson L, and Heby O (1990) Superinduction of ornithine decarboxylase (ODC) by actinomycin D is due to stimulation of ODC mRNA translation. FEBS lett 268:161-164.
30. Yeung SJ and Eskin A (1987) Involvement of a specific protein in the regulation of a circadian rhythm in the Aplysia eye. Proc Natl Acad Sci U S A 84:279-283.
31. Yeung SJ and Eskin A (1988) Responses of the circadian system in the Aplysia eye to inhibitors of protein synthesis. J Biol Rhythms 3:225-236.
32. Zandomeni R, Zandomeni MC, Shugar D, and Weinmann R (1986) Casein kinase type II is involved in the inhibition by 5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription. J Biol Chem 261:3414-3419.