Long-Term Growth Hormone Deficiency as a Cause of Cardiomyopathy and Its Reversibility with Specific Replacement Therapy

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 3, 1996, Pages 887-890

  Fazio, S ^a   Biondi, B ^a   Sabatini, D ^a   Cuocolo, A ^a   Tommaselli, A P ^a   Lombardi, G ^a   Sacca L ^a,b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Medicina Interna   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE;

CARDIOMYOPATHY; CASE REPORT; CHRONIC DISEASE; ECHOCARDIOGRAPHY; ECHOGRAPHY; FEMALE; HUMAN; MIDDLE AGED; REVIEW; ADULT; CONFERENCE PAPER; DOPPLER ECHOGRAPHY; EXERCISE TEST; GROWTH HORMONE DEFICIENCY; HEART SCINTISCANNING; HORMONE SUBSTITUTION; HYPOPITUITARISM; PRIORITY JOURNAL;

CARDIOMYOPATHIES; CHRONIC DISEASE; ECHOCARDIOGRAPHY; FEMALE; GROWTH HORMONE; HUMANS; MIDDLE AGED;

EID: 0030097464     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.81.3.8772545     Document Type: Article

References (19)

1. Cuneo RC, Salomon F, Wilmshurst P, et al. 1991 Cardiovascular effects of growth hormone treatment in growth-hormone-deficient adults: stimulation of the renin-aldosterone system. Clin Sci. 81:587-592.
2. Merola B, Cittadini A, Colao A, et al. 1993 Cardiac structural and functional abnormalities in adult patients with growth hormone deficiency. J Clin Endocrinol Metab. 77:1658-1661.
3. Amato G, Carella C, Fazio S, et al. 1993 Body composition, bone metabolism and heart structure and function in growth hormone (GH)-deficient adults before and after GH replacement therapy at low doses. J Clin Endocrinol Metab. 77:1671-1676.
4. Cittadini A, Cuocolo A, Merola B, et al. 1994 Impaired cardiac performance in growth hormone deficient adults and its improvement after growth hormone replacement. Am J Physiol. 267:E219-E225.
5. Duerr RL, Huang S, Miraliakbar HR, Clark R, Chien K, Ross Jr J. 1995 Insulin-like growth factor-I enhances ventricular hypertrophy and function during the onset of experimental cardiac failure. J Clin Invest. 95:619-627.
6. Ambler GR, Johnson BM, Maxwell L, Gavin JV, Glukman PD. 1993 Improvement of doxorubicin-induced cardiomyopathy in rats treated with insulin-like growth factor 1. Cardiovasc Res. 27:1368-1373.
7. Anand IS, Ferrari R, Karla GS, Wahi PL, Poole-Wilson PA, Harris PC. 1989 Edema of cardiac origin: studies of body water and sodium, renal function, hemodynamic indexes, and plasma hormones in untreated congestive cardiac failure. Circulation. 80:299-305.
8. Anand I, Chandrashekhar Y, Ferrari R, Poole-Wilson P, Harris P. 1992 Growth hormone in syndromes of chronic congestive heart failure [Abstract]. Circulation. 86(Suppl 1):1-668.
9. Ross RJM, Chew SL. 1995 Acquired growth hormone resistance. Eur J Endocrinol. 132:655-660.
10. Kasper EK, Agema WR, Hutchins GM, Deckers JW, Hare JM, Baughman KL. 1994 The causes of dilated cardiomyopathy: a clinicopathologic review of 673 consecutive patients. J Am Coll Card. 23:586-590.
11. Ladenson PW, Sherman SI, Baughman KL, Ray PE, Feldman AM. 1992 Reversible alterations in myocardial gene expression in a young man with dilated cardiomyopathy and hypothyroidism. Proc Natl Acad Sci USA. 89: 5251-5255.
12. Bauerlein EJ, Chakko CS, Kessler KM. 1992 Reversible dilated cardiomyopathy due to thyrotoxicosis. Am J Cardiol. 70:132-134.
13. Moruzzi P, Doria E, Agostoni PG, Capacchione V, Sganzerla P. 1994 Usefulness of L-thyroxine to improve cardiac and exercise performance in idiopathic dilated cardiomyopathy. Am J Cardiol. 73:374-378.
14. Garcia R, Jennings JM. 1972 Pheochromocytoma masquerading as a cardiomyopathy. Am J Cardiol. 29:568-571.
15. Imperato-McGinley J, Gautier T, Ehlers K, Zullo MA, Goldstein DS, Vaugham Jr ED. 1987 Reversibility of catecholamine-induced dilated cardiomyopathy in a child with a pheochromocytoma. N Engl J Med. 316: 793-797.
16. Cuneo RC, Wilmshurst P, Lowy C, McGauley G, Sönksen PH. 1989 Cardiac failure responding to growth hormone. Lancet. 1:838-839.
17. Frustaci A, Perrone GA, Gentiloni N, Russo MA. 1992 Reversible dilated cardiomyopathy due to growth hormone deficiency. Am J Clin Pathol. 97: 503-511.
18. Dec GW, Fuster V. 1994 Idiopathic dilated cardiomyopathy. N Engl J Med 331:1564-1575.
19. Rosén T, Bengtsson B-Å. 1990 Premature mortality due to cardiovascular disease in hypopituitarism. Lancet. 336:285-288.