Glucosinolates in Brassica: Occurrence and significance as cancer-modulating agents

Proceedings of the Nutrition Society

Volumn 55, Issue 1, 1996, Pages 433-446

  Jongen, Wim M F ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSINOLATE;

ANIMAL; BRASSICA; CHEMISTRY; HUMAN; ISOLATION AND PURIFICATION; NEOPLASM; PATHOPHYSIOLOGY; REVIEW;

ANIMALS; BRASSICA; GLUCOSINOLATES; HUMANS; NEOPLASMS;

EID: 0030093637     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1079/PNS19960040     Document Type: Article

References (56)

1. Althaus, F. R., Sinclair, J. F. & Meyer, U. A. (1979). Drug-mediated induction of cytochrome(s) P450 and drug metabolism in cultured hepatocytes maintained in chemically defined medium. Journal of Biological Chemistry 25, 2148-2152.
2. Bailey, G. S., Hendricks, J. D., Shelton, D. W., Nixon, J. E. & Pawlowski, N. E. (1987). Enhancement of carcinogenesis by the natural anticarcinogen indole-3-carbinol. Journal of the National Cancer Institute 78, 931-934.
3. Boyd, J. N., Babish, J. G. & Stoewsand, G. S. (1982). Modification by beet and cabbage diets of aflatoxin B1-induced rat plasma α-fetoprotein elevation, hepatic tumorigenesis and mutagenicity of urine. Food and Chemical Toxicology 20, 47-54.
4. Bradfield, C. A. & Bjeldanes, L. F. (1987). High performance liquid chromatographic analysis of anti-carcinogenic indoles in Brassica oleracea. Journal of Agricultural and Food Chemistry 35, 46-49.
5. Cha, Y. N., Thompson, D. C., Heine, H. S. & Chung, J. H. (1985). Differential effects of indole, indole-3-carbinol and benzofuran on several microsomal and cytosolic enzyme activities in mouse liver. Korean Journal of Pharmacology 21, 1-11.
6. de Vos, R. H. & Blijleven, W. G. H. (1988). The effects of processing on glucosinolate in cruciferous vegetables. Zeitschrift für Lebensmittel-Untersuchung und - Forschung 187, 525-529.
7. Fenwick, G. R. & Heaney, R. K. (1983). Glucosinolates and their breakdown products in cruciferous crops, foods and feedingstuffs. Food Chemistry 11, 249-271.
8. Fenwick, G. R., Heaney, R. K. & Mullin, W. J. (1983). Glucosinolates and their breakdown products in food and food plants. CRC Critical Reviews in Food Science and Nutrition 18, 123-201.
9. Giger, U. & Meyer, U. A. (1981). Role of haem in the induction of cytochrome P450 by phenobarbitone. Biochemical Journal 198, 131-135.
10. ∼, 3-indolylacetonitrile and ascorbigen in Brassica oleracea species. Annales Academiae Scientiarum Fennicae 107, 3-23.
11. ∼85. The Hague, the Netherlands: Landbouw-Economisch Instituut.
12. Graham, S. (1983). Results of case-control studies of diet and cancer in Buffalo, New York. Cancer Research 43, 2409-2413.
13. Graham, S., Dayal, S., Swanson, M., Mittelman, A. & Valikinson, G. (1978). Diet in the epidemiology of cancer of the colon and rectum. Journal of the National Cancer Institute 61, 709-714.
14. Graham, S. & Mettlin, C. (1979). Diet and colon cancer. American Journal of Epidemiology 109, 1-20.
15. Groenen, P. J. & Bussink, E. (1988). Alkylating activity in food products - especially sauerkraut and sour fermented dairy products - after incubation with nitrite under quasi gastric conditions. Food and Chemical Toxicology 26, 215-255.
16. Hill, C. B., Williams, P. H., Carlson, D. G. & Tookey, H. L. (1987). Variation in glucosinolates in oriental brassica vegetables. Journal of American Society of Horticultural Science 112, 309-313.
17. Hirayama, T. (1986). Diet and cancer: feasibility and importance of prospective cohort study. In Diet and Human Carcinogenesis. Proceedings of the Second ECP Symposium, Aarhus, Denmark, p. 191 [J. V. Joossens, M. J. Hill and J. Geboers, editors]. Amsterdam: Excerptica Medica.
18. Jongen, W. M. F. (1988). Co-cultivation of cells as a promising tool in cancer research in vitro. PhD Dissertation, Agricultural University Wageningen, The Netherlands.
19. Jongen, W. M. F. (1993). Toxicological methods to study mechanisms of naturally occurring anticarcinogens. In Food and Cancer Prevention: Chemical and Biological Aspects, pp. 383-396 [K. W. Waldron, I. T. Johnson and G. R. Fenwick, editors]. Cambridge: The Royal Society of Chemistry.
20. Jongen, W. M. F., Alink, G. M., Harmsen, E. G. M. & Koeman, J. H. (1982). The effect of glutathione conjugation and microsomal oxidation on the mutagenicity of dichloromethane in Salmonella typhimurium. Mutation Research 95, 183-187.
21. Jongen, W. M. F., Topp, R. J., Tiedink, H. G. M. & Brink, E. J. (1987). A co-cultivation system as a model for in vitro studies of modulating effects of naturally occurring indoles on genotoxicity of model compounds. Toxicology in vitro 1, 105-110.
22. Jongen, W. M. F., Topp, R. J., van Bladeren, P. J., Lapré, J., Wienk, K. J. H. & Leenen, R. (1989). Modulating effects of indoles on benzo(a)pyrene-induced sister chromatid exchanges and the balance between drug-metabolizing enzymes. Toxicology in vitro 3, 207-213.
23. Loub, W. D., Wattenberg, L. W. & Davis, D. W. (1975). Aryl hydrocarbon hydroxylase induction by naturally occurring indoles in cruciferous plants. Journal of the National Cancer Institute 54, 985-988.
24. McDanell, R., McLean, A. E. M., Hanley, A. B., Heaney, R. K. & Fenwick, G. R. (1988). Chemical and biological properties of indole glucosinolates (glucobrassicin): A review. Food and Chemical Toxicology 26, 59-70.
25. McDanell, R., McLean, A. E. M., Hanley, A. B., Heaney, R. K. & Fenwick, G. R. (1989). The effect of feeding Brassica vegetables and intact glucosinolates on mixed function oxidase activity in livers and intestines of rats. Food and Chemical Toxicology 27, 189-197.
26. McMillan, M., Spinks, E. A. & Fenwick, G. R. (1986). Preliminary observations on the effect of dietary Brussels sprouts on thyroid function. Human Toxicology 5, 15-19.
27. Moldeus, P. (1987). Comparison of model systems for metabolism. In Drug Metabolism: From Molecules to Man, pp. 437-444 [D. Benford, J. W. Bridges and G. G. Gibson, editors]. London: Taylor & Francis.
28. National Toxicological Programme (1981). National Toxicological Programme Technical Report on the Carcinogenesis Bioassay of Isoallylthiocyanate. Triangle Park, NC: National Cancer Institute.
29. Pence, B. C., Buddingh, F. & Yang, S. P. (1986). Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3-carbinol. Journal of the National Cancer Institute 77, 269-276.
30. Piacek-Llanes, B. G. & Tannenbaum, S. R. (1982). Formation of an activated N-nitroso compound in nitrite treated fava beans (Vicia faba). Carcinogenesis 3, 1379-1384.
31. Ponten, J. (1987). Normal versus neoplastic tissue behaviour: what differences are essential? In Concepts and Theories in Carcinogenesis, pp. 3-13 [A. P. Maskens, P. Ebbesen and A. Burny, editors]. Amsterdam: Excerptica Medica.
32. Slaga, T. J. (1984). Multistage skin carcinogenesis: a useful model for the study of the chemoprevention of cancer. Acta Pharmacologica et Toxicologica 55, Suppl., 107-118.
33. Slominski, B. A. & Campbell, L. D. (1987). Gas chromatographic determination of indole glucosinolates a re-examination. Journal of the Science of Food and Agriculture 40, 131-143.
34. Sparnins, V. I., Venegas, P. L. & Wattenberg, L. W. (1982). Glutathione-S-transferase activity: enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents. Journal of the National Cancer Institute 68, 493-495.
35. Srisangham, C., Salunke, D. K., Reddy, N. R. & Dull, G. G. (1980). Quality of cabbage. II. Physical, chemical and biochemical modification in processing treatments to improve flavour of blanched cabbage (Brassica oleracea L.). Journal of Food Quality 3, 233-244.
36. Stoewsand, G. S., Babish, J. B. & Wimberley, H. C. (1978). Inhibition of hepatic toxicities from polybrominated biphenyls and aflatoxin B1 in rats fed cauliflower. Journal of Environmental Pathology and Toxicology 2, 399-404.
37. Tiedink, H. G. M., Davies, J. A. R., van Broekhoven, L. W., van der Kamp, H. J. & Jongen, W. M. F. (1988). Formation of mutagenic N-nitroso compounds in vegetable extracts upon nitrite treatment; a comparison with the glucosinolate content. Food and Chemical Toxicology 26, 947-954.
38. Tiedink, H. G. M., Davies, J. A. R., Visser, N. A., Jongen, W. M. F. & van Broekhoven, L. W. (1989). The stability of the nitrosated products of indole, indole-3-acetonitrile, indole-3-carbinol and 4-chloroindole. Food and Chemical Toxicology 27, 723-730.
39. Tiedink, H. G. M., Hissink, A. M., Lodema, S. M., van Broekhoven, L. W. & Jongen, W. M. F. (1990). Several known indole compounds are not important precursors of direct mutagenic N-nitroso compounds in green cabbage. Mutation Research 232, 199-207.
40. Tiedink, H. G. M., Malingre, C. E., van Broekhoven, L. W., Jongen, W. M. F., Lewis, J. & Fenwick, G. R. (1991). The role of glucosinolates in the formation of N-nitroso compounds. Journal of Agricultural and Food Chemistry 39, 922-926.
41. Topp, R. & van Bladeren, P. J. (1986). Oxydative biotransformation in primary cultures of chick embryo hepatocytes: induction of cytochrome P-450 and the metabolism of Benzo(a)pyrene. Archives of Toxicology 59, 150-156.
42. van Bladeren, P. J. (1993). Modulation of biotransformation enzymes by non-nutritive dietary factors. In Food and Cancer Prevention: Chemical and Biological Aspects, pp. 163-175 [K. W. Waldron, I. T. Johnson and G. R. Fenwick, editors]. Cambridge: The Royal Society of Chemistry.
43. van der Hoeven, J. C. M., Lagerweij, W. J., van Gastel, A., Huitink, J., de Dreu, R. & van Broekhoven, L. W. (1984). Intercultivar difference with respect to mutagenicity of fava beans (Vicia Faba L.) after incubation with nitrite. Mutation Research 130, 391-394.
44. van Etten, G. H. (1969). Goitrogens. In Toxic Constituents of Plant Foodstuffs, pp. 103-142 [I. E. Liener, editor]. New York: Academic Press.
45. van Etten, G. H. & Wolff, I. A. (1973). Natural sulphur compounds. In Toxicants Occurring Naturally in Foods, pp. 210-234. Washington, DC: Committee on Food Protection, Food and Nutrition Board and National Research Council, National Academy of Sciences.
46. Wakabayashi, K., Nagao, M., Ho-Chung, T., Yin, M., Karai, I., Ochiai, M., Tahira, T. & Sugimura, T. (1984). Appearance of direct-acting mutagenicity of various foodstuffs produced in Japan and South-East Asia on nitrite treatment. Mutation Research 158, 119-124.
47. Wakabayashi, K., Nagao, M., Ochiai, M., Tahira, T., Yamaizumi, Z. & Sugimura, T. (1985). A mutagen precursor in Chinese cabbage, indole-3-acetonitrile, which becomes mutagenic on nitrite-treatment. Mutation Research 143, 17-21.
48. Wakabayashi, K., Nagao, M., Tahira, T., Yamaizumi, Z., Katayama, M., Marumo, S. & Sugimura, T. (1986). 4-Methoxyindole derivative as nitrosable precursors of mutagens in Chinese cabbage. Mutagenesis 1, 423-426.
49. Wakabayashi, K., Ochiai, M., Saito, H., Tsuda, M. & Sugimura, T. (1983). Presence of 1-methyl-1,2,3,4-tetrahydro-8-carboline-3-carboxylic acid, a precursor of a mutagenic nitroso compound, in soy sauce. Proceedings of the National Academy of Sciences, USA 80, 2912-2916.
50. Wattenberg, L. W. (1983). Inhibition of neoplasia by minor dietary constituents. Cancer Research 43, 2449s-2453s.
51. Wattenberg, L. W. (1993). Inhibition of carcinogenesis by non-nutrient constituents of the diet. In Food and Cancer Prevention: Chemical and Biological Aspects, pp. 12-24. [K. W. Waldron, I. T. Johnson and G. R. Fenwick, editors]. Cambridge: The Royal Society of Chemistry.
52. Wattenberg, L. W. & Loub, W. D. (1978). Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles. Cancer Research 38, 1410s-1414s.
53. Wattenberg, L. W., Loub, W. D., Lam, L. K. & Speir, J. L. (1976). Dietary constituents altering the response to chemical carcinogens. Federation Proceedings 35, 1327-1331.
54. Wortelboer, H. M., Dekruif, C. A., Vaniersel, A. A. J., Falke, H. E., Noordhoek, J. & Blaauboer, B. J. (1990). The isoenzyme pattern of cytochrome-P450 in rat hepatocytes in primary culture, comparing different enzyme-activities in microsomal incubations and intact monolayers. Biochemical Pharmacology 40, 2525-2534.
55. Wright, A. S. (1980). The role of metabolism in chemical mutagenesis and chemical carcinogenesis. Mutation Research 75, 215-223.
56. Yamaski, H. (1984). Modulation of cell differentiation by tumor promoters. In Mechanisms of Tumor Promotion, vol. 4, pp. 1-43 [T. J. Slaga, editor]. Boca Raton, Florida: CRC Press Inc.