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Volumn 3, Issue 2, 1996, Pages 85-96

Virus and host factors are both important determinants of response to interferon treatment among patients with chronic hepatitis C

Author keywords

Chronic HCV; Host determinants; Response; Virus

Indexed keywords

ALPHA2B INTERFERON;

EID: 0030093219     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2893.1996.tb00086.x     Document Type: Article
Times cited : (30)

References (52)
  • 1
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo Q-L, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989; 244: 359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.-L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 2
    • 0025150610 scopus 로고
    • Hepatitis C virus and its relationship to the clinical spectrum of NANB hepatitis
    • Alter HJ. Hepatitis C virus and its relationship to the clinical spectrum of NANB hepatitis. J Gastroenterol Hepatol 1990; 5 (Suppl 1): 78-94.
    • (1990) J Gastroenterol Hepatol , vol.5 , Issue.1 SUPPL. , pp. 78-94
    • Alter, H.J.1
  • 3
    • 0024368522 scopus 로고
    • Treatment of chronic hepatitis C with recombinant interferon-α. A multicenter, randomized, controlled trial
    • Davis GL, Balart LA. Schiff ER and the Hepatitis Interventional Therapy Group. Treatment of chronic hepatitis C with recombinant interferon-α. A multicenter, randomized, controlled trial. N Engl J Med 1989; 301: 1501-1506.
    • (1989) N Engl J Med , vol.301 , pp. 1501-1506
    • Davis, G.L.1    Balart, L.A.2    Schiff, E.R.3
  • 4
    • 0024981607 scopus 로고
    • Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial
    • Di Bisceglie AM, Martin P, Kassianides C, Lisker-Melman M, Murray L, Waggoner J. Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. N Engl J Med 1989; 321: 1506-1510.
    • (1989) N Engl J Med , vol.321 , pp. 1506-1510
    • Di Bisceglie, A.M.1    Martin, P.2    Kassianides, C.3    Lisker-Melman, M.4    Murray, L.5    Waggoner, J.6
  • 5
    • 0025732689 scopus 로고
    • Recombinant human α-interferon in patients with chronic non-A, non-B hepatitis: A multicentre randomised controlled trial from France
    • Marcellin P, Boyer N, Giostra E, Degott C, Courouce AM, Degos F. Recombinant human α-interferon in patients with chronic non-A, non-B hepatitis: a multicentre randomised controlled trial from France. Hepatology 1991; 13: 393-397.
    • (1991) Hepatology , vol.13 , pp. 393-397
    • Marcellin, P.1    Boyer, N.2    Giostra, E.3    Degott, C.4    Courouce, A.M.5    Degos, F.6
  • 6
    • 0025768539 scopus 로고
    • Comparison of 1 or 3 MU of interferon α-2b and placebo in patients with chronic non-A, non-B hepatitis
    • Causse X, Godinot H, Chevallier M, Chossegros P, Zoulin F, Ouzan D. Comparison of 1 or 3 MU of interferon α-2b and placebo in patients with chronic non-A, non-B hepatitis. Gastroenterology 1991; 101: 497-502.
    • (1991) Gastroenterology , vol.101 , pp. 497-502
    • Causse, X.1    Godinot, H.2    Chevallier, M.3    Chossegros, P.4    Zoulin, F.5    Ouzan, D.6
  • 7
    • 0026179761 scopus 로고
    • Can the response to interferon treatment be predicted in patients with chronic active hepatitis C?
    • Lin R, Schoeman MN, Craig PI, Bilous M, Grierson J, McDonald JA. Can the response to interferon treatment be predicted in patients with chronic active hepatitis C? Aust NZ J Med 1991; 21: 387-392.
    • (1991) Aust NZ J Med , vol.21 , pp. 387-392
    • Lin, R.1    Schoeman, M.N.2    Craig, P.I.3    Bilous, M.4    Grierson, J.5    McDonald, J.A.6
  • 8
    • 0027481146 scopus 로고
    • Randomized controlled trial of recombinant α-2a-interferon for chronic hepatitis C. Comparison of alanine aminotransferase normalization versus loss of HCV RNA and anti-HCV IgM
    • Douglas DD, Rakela J, Lin HJ, Hollinger FB, Taswell HF, Czaja AJ. Randomized controlled trial of recombinant α-2a-interferon for chronic hepatitis C. Comparison of alanine aminotransferase normalization versus loss of HCV RNA and anti-HCV IgM. Dig Dis Sci 1993; 38: 601-607.
    • (1993) Dig Dis Sci , vol.38 , pp. 601-607
    • Douglas, D.D.1    Rakela, J.2    Lin, H.J.3    Hollinger, F.B.4    Taswell, H.F.5    Czaja, A.J.6
  • 9
    • 24844443081 scopus 로고
    • α-interferon 2b (IFN) in the treatment of chronic active hepatitis C: Interim report of the first multicentre Australian trial
    • Lin R, Zimmerman M, Roach E, Farrell GC. α-interferon 2b (IFN) in the treatment of chronic active hepatitis C: interim report of the first multicentre Australian trial. Hepatology 1992; 16: 75A.
    • (1992) Hepatology , vol.16
    • Lin, R.1    Zimmerman, M.2    Roach, E.3    Farrell, G.C.4
  • 10
    • 28644433392 scopus 로고
    • Treatment of chronic hepatitis non-A, non-B with recombinant interferon (r-IFN) α
    • Ferenci P, Vogel W, Pristatuz G et al. Treatment of chronic hepatitis non-A, non-B with recombinant interferon (r-IFN) α. Hepatology 1988; 8: 1268.
    • (1988) Hepatology , vol.8 , pp. 1268
    • Ferenci, P.1    Vogel, W.2    Pristatuz, G.3
  • 11
    • 0025639973 scopus 로고
    • A randomized, double-blind, placebo-controlled trial of recombinant human α-interferon therapy for chronic non-A, non-B (type C) hepatitis
    • Di Bisceglie AM, Martin P, Kassianides C et al. A randomized, double-blind, placebo-controlled trial of recombinant human α-interferon therapy for chronic non-A, non-B (type C) hepatitis. J Hepatol 1990; 11: s36-s42.
    • (1990) J Hepatol , vol.11
    • Di Bisceglie, A.M.1    Martin, P.2    Kassianides, C.3
  • 12
    • 0025740921 scopus 로고
    • Treatment of chronic hepatitis C
    • Hess G. Treatment of chronic hepatitis C. J Hepatol 1991; 1: s17-s20.
    • (1991) J Hepatol , vol.1
    • Hess, G.1
  • 13
    • 0027934395 scopus 로고
    • Factors predictive of the response to interferon in patients with chronic hepatitis C
    • Serfaty L, Giral P, Loria A, Andreani T, Legendre C, Poupon R. Factors predictive of the response to interferon in patients with chronic hepatitis C. J Hepatol 1994; 21: 12-17.
    • (1994) J Hepatol , vol.21 , pp. 12-17
    • Serfaty, L.1    Giral, P.2    Loria, A.3    Andreani, T.4    Legendre, C.5    Poupon, R.6
  • 14
    • 0027322553 scopus 로고
    • Response related factors in recombinant interferon α-2b treatment of chronic hepatitis C
    • Perez R, Pravia R, Linares, Rodriguez M, Lombrana JL, Suarez A. Response related factors in recombinant interferon α-2b treatment of chronic hepatitis C. Gut 1993; 34 (2 Suppl): s139-s140.
    • (1993) Gut , vol.34 , Issue.2 SUPPL.
    • Perez, R.1    Pravia, R.2    Linares3    Rodriguez, M.4    Lombrana, J.L.5    Suarez, A.6
  • 15
    • 0025637179 scopus 로고
    • Therapy of chronic post-transfusion non-A, non-B hepatitis with interferon α-2b: Swedish experience
    • Weiland O, Schvarcz R, Wejstal R, Norkrans G, Fryden A. Therapy of chronic post-transfusion non-A, non-B hepatitis with interferon α-2b: Swedish experience. J Hepatol 1990; 11 (Suppl 1): s57-s62.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Weiland, O.1    Schvarcz, R.2    Wejstal, R.3    Norkrans, G.4    Fryden, A.5
  • 16
    • 0025671750 scopus 로고
    • A randomized controlled trial of interferon-α-2b as therapy for chronic non-A, non-B hepatitis
    • Saracco G, Rosina F, Torrani Cerenzia MR, Lattore V, Chiandussi L. A randomized controlled trial of interferon-α-2b as therapy for chronic non-A, non-B hepatitis. J Hepatol 1990; 11 (Suppl. 1): s43-s49.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Saracco, G.1    Rosina, F.2    Torrani Cerenzia, M.R.3    Lattore, V.4    Chiandussi, L.5
  • 17
    • 0027192163 scopus 로고
    • Histological difference between complete responders and non-responders to interferon therapy of the livers of patients with chronic hepatitis C
    • Uchida T, Taira M, Shikata T et al. Histological difference between complete responders and non-responders to interferon therapy of the livers of patients with chronic hepatitis C. Acta Pathol Jpn 1993; 43: 230-236.
    • (1993) Acta Pathol Jpn , vol.43 , pp. 230-236
    • Uchida, T.1    Taira, M.2    Shikata, T.3
  • 18
    • 0027263049 scopus 로고
    • Results of long term interferon treatment in non-A non-B/C chronic active hepatitis. The French group for the study of NANB/C hepatitis treatment
    • Metreau JM. Results of long term interferon treatment in non-A non-B/C chronic active hepatitis. The French group for the study of NANB/C hepatitis treatment. Gut 1993; 34 (2 Suppl): s112-s113.
    • (1993) Gut , vol.34 , Issue.2 SUPPL.
    • Metreau, J.M.1
  • 19
    • 0027404908 scopus 로고
    • Quantitative analysis of hepatitis C virus RNA in serum during inteferon α therapy
    • Hagiwara H, Hayashi N, Mita E et al. Quantitative analysis of hepatitis C virus RNA in serum during inteferon α therapy. Gastroenterology 1993; 104: 877-883.
    • (1993) Gastroenterology , vol.104 , pp. 877-883
    • Hagiwara, H.1    Hayashi, N.2    Mita, E.3
  • 20
    • 0027279599 scopus 로고
    • Effect of lymphoblastoid α-interferon in patients with chronic hepatitis C having different genotypic subtype of hepatitis C virus
    • Chayama K, Tsubota A, Arase Y, Saitoh S, Ikeda K, Matsumoto T. Effect of lymphoblastoid α-interferon in patients with chronic hepatitis C having different genotypic subtype of hepatitis C virus. Gastroenterol Jpn 1993; 28 Suppl 5: 45-47.
    • (1993) Gastroenterol Jpn , vol.28 , Issue.5 SUPPL. , pp. 45-47
    • Chayama, K.1    Tsubota, A.2    Arase, Y.3    Saitoh, S.4    Ikeda, K.5    Matsumoto, T.6
  • 21
    • 0026734297 scopus 로고
    • Detection of hepatitis C virus by polymerase chain reaction and response to interferon-α therapy: Relationship to genotypes of hepatitis C virus
    • Yoshioka K, Kakumu S, Wakita T, Ishikawa T, Itoh Y, Takayanagai M. Detection of hepatitis C virus by polymerase chain reaction and response to interferon-α therapy: relationship to genotypes of hepatitis C virus. Hepatology 1992; 16: 293-299.
    • (1992) Hepatology , vol.16 , pp. 293-299
    • Yoshioka, K.1    Kakumu, S.2    Wakita, T.3    Ishikawa, T.4    Itoh, Y.5    Takayanagai, M.6
  • 22
    • 0028204083 scopus 로고
    • Factors predictive of response to interferon-α therapy in hepatitis C virus infection
    • Tsubota A, Chayama K, Ikeda K, Yasuji A, Koida I, Saitoh S. Factors predictive of response to interferon-α therapy in hepatitis C virus infection. Hepatology 1994; 19: 1088-1094.
    • (1994) Hepatology , vol.19 , pp. 1088-1094
    • Tsubota, A.1    Chayama, K.2    Ikeda, K.3    Yasuji, A.4    Koida, I.5    Saitoh, S.6
  • 24
    • 0028263211 scopus 로고
    • Genotypes and titres of hepatitis C virus for predicting response to interferon in patients with chronic hepatitis C
    • Hino K, Sainokami S, Shimoda K, Iino S, Wang Y, Okamoto H. Genotypes and titres of hepatitis C virus for predicting response to interferon in patients with chronic hepatitis C. J Med Virol 1994; 42: 299-305.
    • (1994) J Med Virol , vol.42 , pp. 299-305
    • Hino, K.1    Sainokami, S.2    Shimoda, K.3    Iino, S.4    Wang, Y.5    Okamoto, H.6
  • 25
    • 0028239921 scopus 로고
    • Predicting interferon therapy efficacy from hepatitis C virus genotype and RNA titre
    • Mita E, Hayashi N, Hagiwara H, Ueda K, Kanazawa Y, Kasahara A. Predicting interferon therapy efficacy from hepatitis C virus genotype and RNA titre. Dig Dis Sci 1994; 39: 977-982.
    • (1994) Dig Dis Sci , vol.39 , pp. 977-982
    • Mita, E.1    Hayashi, N.2    Hagiwara, H.3    Ueda, K.4    Kanazawa, Y.5    Kasahara, A.6
  • 26
    • 0027276247 scopus 로고
    • Significance of serum hepatitis C virus RNA levels in chronic hepatitis C
    • Lau JYN, Davis GL, Kniffen J, Qian KP, Urdea MS, Chan C. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 1993; 341: 1501-1504.
    • (1993) Lancet , vol.341 , pp. 1501-1504
    • Lau, J.Y.N.1    Davis, G.L.2    Kniffen, J.3    Qian, K.P.4    Urdea, M.S.5    Chan, C.6
  • 27
    • 0026664433 scopus 로고
    • At least five related, but distinct, hepatitis C viral genotypes exist
    • Cha TA, Beall E, Irvine J et al. At least five related, but distinct, hepatitis C viral genotypes exist. Proc Natl Acad Sci USA 1992; 89: 7144-7148.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7144-7148
    • Cha, T.A.1    Beall, E.2    Irvine, J.3
  • 28
    • 84989559703 scopus 로고
    • Hepatitis C virus genotypes: An investigation of type-specific differences in geographic origin and disease
    • Dusheiko G, Schmilovitz-Weiss H, Brown D, McOmish F, Yap PL, Sherklock S. Hepatitis C virus genotypes: an investigation of type-specific differences in geographic origin and disease. Hepatology 1994; 19: 13-18.
    • (1994) Hepatology , vol.19 , pp. 13-18
    • Dusheiko, G.1    Schmilovitz-Weiss, H.2    Brown, D.3    McOmish, F.4    Yap, P.L.5    Sherklock, S.6
  • 30
    • 0026072529 scopus 로고
    • Classification of chronic viral hepatitis: A need for reassessment
    • Scheuer PJ. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol 1991; 13: 372-374.
    • (1991) J Hepatol , vol.13 , pp. 372-374
    • Scheuer, P.J.1
  • 31
    • 0028241378 scopus 로고
    • Quantitative detection of hepatitis C virus RNA with a solid phase signal amplification method: Definition of optimal conditions for specimen collection and clinical application in interferon-treated patients
    • Davis GL, Lau JYN, Urdea MS, Neuwald PD, Wilber JC, Lindsay K. Quantitative detection of hepatitis C virus RNA with a solid phase signal amplification method: definition of optimal conditions for specimen collection and clinical application in interferon-treated patients. Hepatology 1994; 19: 1337-1341.
    • (1994) Hepatology , vol.19 , pp. 1337-1341
    • Davis, G.L.1    Lau, J.Y.N.2    Urdea, M.S.3    Neuwald, P.D.4    Wilber, J.C.5    Lindsay, K.6
  • 33
    • 0024973417 scopus 로고
    • Avoiding false positives with PCR
    • Kwok S, Higuchi R. Avoiding false positives with PCR. Nature 1989; 339: 237-238.
    • (1989) Nature , vol.339 , pp. 237-238
    • Kwok, S.1    Higuchi, R.2
  • 34
    • 0021099452 scopus 로고
    • Reverse transcriptase and its associated ribonuclease H: Interplay of two enzymes activity controls the yield of single-stranded complementary deoxyribonucleic acid
    • Berger SL, Wallace DM, Puskas RS, Eschenfeldt WH. Reverse transcriptase and its associated ribonuclease H: interplay of two enzymes activity controls the yield of single-stranded complementary deoxyribonucleic acid. Biochemistry 1983; 22: 2365-2372.
    • (1983) Biochemistry , vol.22 , pp. 2365-2372
    • Berger, S.L.1    Wallace, D.M.2    Puskas, R.S.3    Eschenfeldt, W.H.4
  • 35
    • 0026786405 scopus 로고
    • Standardization of MRNA titration using a polymerase chain reaction method involving coamplification with a multispecific internal control
    • Bouaboula M, Legoux P, Pessegue B, Delpech B, Dumont X, Piechaczyk M. Standardization of MRNA titration using a polymerase chain reaction method involving coamplification with a multispecific internal control. J Biol Chem 1992; 267: 21 830-838.
    • (1992) J Biol Chem , vol.267 , pp. 21830-21838
    • Bouaboula, M.1    Legoux, P.2    Pessegue, B.3    Delpech, B.4    Dumont, X.5    Piechaczyk, M.6
  • 37
    • 0028679478 scopus 로고
    • Clinical predictors of response to recombinant inteferon-α treatment in patients with chronic non-A, non-B hepatitis (hepatitis C)
    • Davis GL, Lindsay K, Albrecht J and the Hepatitis Interventional Therapy Group. Clinical predictors of response to recombinant inteferon-α treatment in patients with chronic non-A, non-B hepatitis (hepatitis C). J Viral Hepatitis 1994; 1: 55-63.
    • (1994) J Viral Hepatitis , vol.1 , pp. 55-63
    • Davis, G.L.1    Lindsay, K.2    Albrecht, J.3
  • 38
    • 0027385541 scopus 로고
    • Prediction of the response of chronic hepatitis C to interferon α: A statistical analysis of pretreatment variables
    • Camps J, Crisostomo S, Garcia-Granero M, Riezu-Boj JI, Civeira MP, Prieto J. Prediction of the response of chronic hepatitis C to interferon α: a statistical analysis of pretreatment variables. Gut 1993; 34: 1714-1717.
    • (1993) Gut , vol.34 , pp. 1714-1717
    • Camps, J.1    Crisostomo, S.2    Garcia-Granero, M.3    Riezu-Boj, J.I.4    Civeira, M.P.5    Prieto, J.6
  • 40
    • 0028091162 scopus 로고
    • Hepatitis C viraemia in chronic liver disease: Relationship to interferon-α or corticosteroid treatment
    • Margin S, Craxi A, Fabiano C, Simonetti RG, Fiorentino G, Marino L. Hepatitis C viraemia in chronic liver disease: relationship to interferon-α or corticosteroid treatment. Hepatology 1994; 19: 273-279.
    • (1994) Hepatology , vol.19 , pp. 273-279
    • Margin, S.1    Craxi, A.2    Fabiano, C.3    Simonetti, R.G.4    Fiorentino, G.5    Marino, L.6
  • 41
    • 0027501361 scopus 로고
    • Appropriate interferon-α therapy for chronic hepatitis C: An assessment by quantitative changes in serum hepatitis C virus RNA
    • Watanabe S, Kobayashi Y, Konishi M et al. Appropriate interferon-α therapy for chronic hepatitis C: an assessment by quantitative changes in serum hepatitis C virus RNA. Intern-Med 1993; 32: 523-529.
    • (1993) Intern-Med , vol.32 , pp. 523-529
    • Watanabe, S.1    Kobayashi, Y.2    Konishi, M.3
  • 42
    • 0028321690 scopus 로고
    • Comparison of quantitative cDNA-PCR with the branched DNA hybridization assay for monitoring plasma hepatitis C virus RNA levels in haemophilia patients participating in a controlled interferon trial
    • Bresters D, Cuypers HTM, Reesink HW, Mauser-Bunschoten EP, Van den Berg HM, Schaasberg WP. Comparison of quantitative cDNA-PCR with the branched DNA hybridization assay for monitoring plasma hepatitis C virus RNA levels in haemophilia patients participating in a controlled interferon trial. J Med Virol 1994; 43: 262-268.
    • (1994) J Med Virol , vol.43 , pp. 262-268
    • Bresters, D.1    Cuypers, H.T.M.2    Reesink, H.W.3    Mauser-Bunschoten, E.P.4    Van Den Berg, H.M.5    Schaasberg, W.P.6
  • 43
    • 0028258029 scopus 로고
    • Quantitative detection of hepatitis C virus genome in liver tissue and circulation by compeitive reverse-transcription polymerase chain reaction
    • Nakagawa H, Shimomura H, Hasui T, Tsuji H, Tsuji T. Quantitative detection of hepatitis C virus genome in liver tissue and circulation by compeitive reverse-transcription polymerase chain reaction. Dig Dis Sci 1994; 39: 225-233.
    • (1994) Dig Dis Sci , vol.39 , pp. 225-233
    • Nakagawa, H.1    Shimomura, H.2    Hasui, T.3    Tsuji, H.4    Tsuji, T.5
  • 44
    • 0027167523 scopus 로고
    • Quantification of hepatitis C virus by competitive transcription-polymerase chain reaction: Increase of the virus in advanced liver disease
    • Kato N, Yokosuka O, Hosoda K, Ito Y, Ohto M, Omata M. Quantification of hepatitis C virus by competitive transcription-polymerase chain reaction: increase of the virus in advanced liver disease. Hepatology 1993; 18: 16-20.
    • (1993) Hepatology , vol.18 , pp. 16-20
    • Kato, N.1    Yokosuka, O.2    Hosoda, K.3    Ito, Y.4    Ohto, M.5    Omata, M.6
  • 45
    • 0027461414 scopus 로고
    • Quantitation of hepatitis C virus RNA in serum of asymptomatic blood donors and patients with type C chronic liver disease
    • Hagiwara H, Hayashi N, Mita E, et al. Quantitation of hepatitis C virus RNA in serum of asymptomatic blood donors and patients with type C chronic liver disease. Hepatology 1993; 17: 545-550.
    • (1993) Hepatology , vol.17 , pp. 545-550
    • Hagiwara, H.1    Hayashi, N.2    Mita, E.3
  • 46
    • 9444241084 scopus 로고
    • Predictors of relapse and response to re-treatment in patients with an initial response to recombinant α interferon (rIFN) therapy for chronic hepatitis C
    • Abstr
    • Lindsay KL, Davis GL, Bodenheimer HC Jr, and the Hepatitis Interventional Therapy Group. Predictors of relapse and response to re-treatment in patients with an initial response to recombinant α interferon (rIFN) therapy for chronic hepatitis C. Hepatology 1990; 12: 847 (Abstr).
    • (1990) Hepatology , vol.12 , pp. 847
    • Lindsay, K.L.1    Davis, G.L.2    Bodenheimer Jr., H.C.3
  • 47
    • 0028331837 scopus 로고
    • Interferon-α for chronic hepatitis C: An analysis of pretreatment clinical predictors of response
    • Pagliaro L, Craxi A, Cammaa C et al. Interferon-α for chronic hepatitis C: an analysis of pretreatment clinical predictors of response. Hepatology 1994; 19: 820-828.
    • (1994) Hepatology , vol.19 , pp. 820-828
    • Pagliaro, L.1    Craxi, A.2    Cammaa, C.3
  • 48
    • 0023180194 scopus 로고
    • Loss of HBsAg with interferon therapy in chronic hepatitis B virus infection
    • Alexander GJM, Brahm J, Fagan EA et al. Loss of HBsAg with interferon therapy in chronic hepatitis B virus infection. Lancet 1987; ii: 66-69.
    • (1987) Lancet , vol.2 , pp. 66-69
    • Alexander, G.J.M.1    Brahm, J.2    Fagan, E.A.3
  • 49
    • 0027214879 scopus 로고
    • Benelux multicentre trial of α interferon for chronic hepatitis C: Standard vs high dose treatment monitored by biochemical and virological markers (interim analyis)
    • Benelux Multicentre Trial Study Group. Benelux multicentre trial of α interferon for chronic hepatitis C: standard vs high dose treatment monitored by biochemical and virological markers (interim analyis). Gut 1993; 34 (2 Suppl): s119-s120.
    • (1993) Gut , vol.34 , Issue.2 SUPPL.
  • 50
    • 0027273859 scopus 로고
    • Efficacy of different regimens of interferon α-2b treatment in chronic hepatitis C
    • De Bac C, Grimaldi F, Clementi C, Duca F, Livoli D, Taliani G. Efficacy of different regimens of interferon α-2b treatment in chronic hepatitis C. Gut 1993; 34 (2 Suppl): s135.
    • (1993) Gut , vol.34 , Issue.2 SUPPL.
    • De Bac, C.1    Grimaldi, F.2    Clementi, C.3    Duca, F.4    Livoli, D.5    Taliani, G.6
  • 51
    • 0027478886 scopus 로고
    • Antiviral therapy for hepatitis C - Present and future
    • Hoofnagle JH, Di Bisceglie AM, Shindo M. Antiviral therapy for hepatitis C - present and future. J Hepatol 1993; 17 (Suppl 3): 130-136.
    • (1993) J Hepatol , vol.17 , Issue.3 SUPPL. , pp. 130-136
    • Hoofnagle, J.H.1    Di Bisceglie, A.M.2    Shindo, M.3
  • 52
    • 0028012650 scopus 로고
    • High sustained response rate and clearance of viremia in chronic hepatitis C after treatment with interferon-α2b for 60 weeks
    • Reichard O, Foberg U, Fryden A, Mattsson L, Norkrans G, Sonnerborg A. High sustained response rate and clearance of viremia in chronic hepatitis C after treatment with interferon-α2b for 60 weeks. Hepatology 1994; 19: 280-285.
    • (1994) Hepatology , vol.19 , pp. 280-285
    • Reichard, O.1    Foberg, U.2    Fryden, A.3    Mattsson, L.4    Norkrans, G.5    Sonnerborg, A.6


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