Synthesis of cobalamin-biotin conjugates that vary in the position of cobalamin coupling. Evaluation of cobalamin derivative binding to transcobalamin II

Bioconjugate Chemistry

Volumn 7, Issue 2, 1996, Pages 217-232

  Pathare, Pradip M ^b   Wilbur, D Scott ^a   Heusser, Shannon ^b   Quadros, Edward V ^c   McLoughlin, Patricia ^c   Charles Morgan, A ^b,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Receptagen Corporation

Author keywords

[No Author keywords available]

Indexed keywords

CHAINS; COBALT;

BINDING PROTEINS; BIOTIN BINDING; COBALAMIN DERIVATIVE; CORRINS; IN-VITRO; PROPIONAMIDES; SIDE-CHAINS; STERICS; VITRO AND IN VIVO; VIVO APPLICATIONS;

COENZYMES;

BIOTIN; COBALT; CYANOCOBALAMIN; DRUG DERIVATIVE; LACTONE; RECOMBINANT PROTEIN; RIBOSE; TRANSCOBALAMIN;

ARTICLE; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; HYDROLYSIS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; SYNTHESIS;

BINDING, COMPETITIVE; BIOTIN; COBALT; HUMANS; HYDROLYSIS; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PROTEIN BINDING; RECOMBINANT PROTEINS; RIBOSE; TRANSCOBALAMINS; VITAMIN B 12;

EID: 0030091598     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9600022     Document Type: Article

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