Protein synthesis: Imprinting through molecular mimicry

Current Biology

Volumn 6, Issue 3, 1996, Pages 247-249

  Liljas, Anders ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; ELONGATION FACTOR G; ELONGATION FACTOR TU; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; TRANSFER RNA;

CHEMISTRY; METABOLISM; MOLECULAR MIMICRY; PROTEIN CONFORMATION; PROTEIN SYNTHESIS; REVIEW;

GTP PHOSPHOHYDROLASE-LINKED ELONGATION FACTORS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MOLECULAR MIMICRY; PEPTIDE ELONGATION FACTOR G; PEPTIDE ELONGATION FACTOR TU; PEPTIDE ELONGATION FACTORS; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; RNA, TRANSFER;

EID: 0030091227     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00469-4     Document Type: Article

References (12)

1. Kaziro Y: The role of guanosine-5′-triphosphate in polypeptide elongation. Biochim Biophys Acta 1978, 505:95-127.
2. Liljas A, Garber M: Ribosomal proteins and elongation factors. Curr Opin Struct Biol 1995, 5:721-727.
3. Kjeldgaard M, Nyborg J: Refined structure of elongation factor Tu from Escherichia coli. J Mol Biol 1992, 223:721-742.
4. Kjeldgaard M, Nissen P, Thirup S, Nyborg J: The crystal structure of elongation factor Tu from Thermus aquaticus in the GTP conformation. Structure 1993, 1:35-50.
5. Berchtold H, Reshetnikova L, Reiser COA, Schirmer NK, Sprinzl M, Hilgenfeld R: Crystal structure of active elongation factor Tu reveals major domain rearrangements. Nature 1993, 365:126-132.
6. Phe, EF-Tu and a GTP analogue. Science 1995, 270:1464-1472.
7. Kawashima T, Berthet-Colominas C, Wulff M, Cusack S, Leberman R: The structure of the Escherichia coli EF-Tu·EF-Ts complex at 2.5 Ȧ resolution. Nature 1996, 379:511-518.
8. Czworkowski J, Wang J, Steitz TA, Moore PB: The crystal structure of elongation factor G complexed with GDP at 2.7 Ä resolution. EMBO J 1994, 13:3661-3668.
9. Ævarsson A, Brazhnikov E, Garber M, Zheltonosova J, Chirgadze Yu, Al-Karadaghi S, Svensson LA, Liljas A: Three-dimensional structure of the ribosomal translocase: elongation factor G from Thermus thermophilus. EMBO J 1994, 13:3669-3677.
10. Ævarsson A: Structure-based sequence alignment of elongation factors EF-Tu and G with related GTPases involved in translation. J Mol Evolution, 1995, 41:1096-1104.
11. Murzin A: A ribosomal protein module in EF-G and DNA gyrase. Nature Struct Biol 1995, 2:25-26.
12. Johansson U, Hughes D: Fusidic acid-resistant mutants define three regions in elongation factor G of Salmonella typhimurium. Gene 1994, 143:55-59.