Artemether-pyrimethamine in the treatment of pyrimethamine-resistant falciparum malaria

Southeast Asian Journal of Tropical Medicine and Public Health

Volumn 27, Issue 1, 1996, Pages 19-23

  Na Bangchang, Kesara ^a   Tipwangso, Pongsri ^a   Thanavibul, Aurathai ^a   Tan ariya, Peerapan ^a   Suprakob, Krit ^b   Kanda, Tozo ^c   Karbwang, Juntra ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b Malaria Sector 4 ^*  (Thailand)

^c Japan Assoc of Tropical Medicine   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ DERIVATIVE; PYRIMETHAMINE; SESQUITERPENE;

ADOLESCENT; ADULT; ANIMAL; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG COMBINATION; DRUG EFFECT; FEMALE; HUMAN; MALARIA FALCIPARUM; MALE; MIDDLE AGED; MULTIDRUG RESISTANCE; PARASITOLOGY; PLASMODIUM FALCIPARUM; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADOLESCENT; ADULT; ANIMALS; ANTIMALARIALS; ARTEMISININS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE, MULTIPLE; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALE; MIDDLE AGED; PLASMODIUM FALCIPARUM; PYRIMETHAMINE; SESQUITERPENES; TREATMENT OUTCOME;

EID: 0030090108     PISSN: 01251562     EISSN: 26975718     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Bunnag D, Karbwang J, Viravan C, Chitamas, Harinasuta T. Clinical trials of mefloquine with tetracycline. Southeast Asian J Trop Med Public Health 1991a; 23 : 377-82
2. Bunnag D, Viravan C, Looareesuwan S, et al. Clinical trial of artesunate and artemether on multidrutg resistant falciparum malaria in Thailand: a preliminary report. Southeast Asian J Trop Med Public Health 1991b; 22 : 380-5.
3. Bunnag D, Karbwang J, Harinasuta T. Artemether in the treatment of multiple drug resistant falciparum malaria. Southeast Asian J Trop Med Public Health 1992; 23 : 762-7.
4. Bunnag D, Kanda T, Karbwang J, Thimasarn K, Pungpak S, et al. Artemether-mefloquine combination in multidrug resistant falciparum malaria. Trans R Soc Trop Med Hyg 1995; 89 : 213-5.
5. Chawira AN, Warhurst DC, Robinson BL, et al. The effect of combinations of qinghaosu (artemisinin) with standard antimalarial drugs in the suppressive treatment of malaria in mice. Trans R Soc Trop Med Hyg 1987; 81 : 554-8.
6. Doberstyn EB, Hall AP, Vetvutanapibul K, Sonkom P. Single dose therapy of falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine. Am J Trop Med Hyg 1976; 25 : 14-9.
7. Harinasuta T, Suntharasamai P, Viravan C. Chloroquine resistant falciparum in Thailand. Lancet 1965; 2 : 657.
8. Harinasuta T, Bunnag D, Vanijanonta S, et al. Mefloquine, sulfadoxine and pyrimethamine in the treatment of symptomatic falciparum malaria: a double blind trial for determining the most effective dose. Bull WHO 1987; 3 : 363-7.
9. Karbwang J, Na-Bangchang K, Molunto P, Bunnag D. Determination of quinine and quinidine in biological fluids by high performance liquid chromatography. Southeast Asian J Trop Med Public Health 1991a; 20 : 65-9.
10. Karbwang J, Molunto P, Na-Bangchang K, Bunnag D. Determination of mefloquine in biological fluids by high performance liquid chromatography. Southeast Asian J Trop Med Public Health 1991b; 20 : 55-60.
11. Karbwang J, Harinasuta T. Distribution of drug resistance. In: Karbwang J, Harinasuta T, eds. Chemotherapy of Malaria in Southeast Asia. Bangkok: Roumtassana, 1992a: 47-62.
12. Karbwang J, Na-Bangchang K, Thanavibul A, Bunnag D, Chongsuphajaisiddi T, Harinasuta T. Comparison of oral artemether and mefloquine in acute uncomplicated falciparum malaria. Lancet 1992b; 2 : 1245-8.
13. Karbwang J, Mungthin M, Thanavibul A, Na-Bangchang K, Harinasuta T. Artemether saved a patient with severe falciparum malaria after quinine treatment failure (RIII type of quinine resistance). Southeast Asian J Trop Med Public Health 1994a; 25 : 782-3.
14. Karbwang J, Na-Bangchang K, Thanavibul A, et al. Comparison of oral artesunate and quinine plus tetracycline in acute uncomplicated falciparum malaria. Bull WHO 1994b; 72 : 233-8.
15. Karbwang J, Na-Bangchang K, Thanavibul A, Ditta-in M, Harinasuta T. A comparative clinical trial of two different regimens of artemether plus mefloquine in multidrug resistant falciparum malaria. Trans R Soc Trop Med Hyg 1995; 89 : 296-8.
16. Ketrangsee S, Vijayakadga S, Yamokgul P, Jatapadma S, Thimasarn K, Rooney W. Comparative trial on the response of Plasmodium falciparum to halofantrine and mefloquine in Trad Province, Eastern Thailand. Southeast Asian J Trop Med Public Health 1992; 23 : 55-8.
17. Li G, Liang R, Wang Z, Jian H, Li Z. Clinical studies on treatment of cerebral malaria with qinghaosu and its derivatives. J Trad Chin Med 1982; 2 : 125-30.
18. Myint PT, Shwe T. The efficacy of artemether (Qinghaosu) in Plasmodium falciparum and P. vivax in Burma. Southeast Asian J Trop Med Public Health 1986; 17 : 19-22.
19. Na-Bangchang K, Karbwang J, Thomas CG, et al. Pharmacokinetics of artemether after oral administration to healthy Thai patients with acute, uncomplicated falciparum malaria Br J Clin Pharmacol 1994; 37 : 249-53.
20. Pinichpongse S, Doberstyn EB, Culen JR. An evaluation of five regimens for the outpatient therapy of falciparum in Thailand. Bull WHO 1982; 60 : 907-912.
21. Rieckman KH, Campel GH, Sax LJ, Mrema JE. Drug sensitivity in Plasmodium falciparum: an in vitro micro-technique. Lancet 1979; 1 : 22-3.
22. Weidekamm E, Plozza-Notterbrock H, Forgo I, Dabach UC. Plasma concentration of pyrimethamine and sulfadoxine and evaluation of pharmacokinetic data by computerized curve fitting. Bull WHO 1982; 60 : 115-22.
23. Wernsdorfer WH, Payne D. The dynamics of drug resistance in Plasmodium falciparum Pharmacol Ther 1991; 50 : 95-121.
24. Wernsdorfer WH. Epidemiology of drug resistance in malaria. Acta Tropica 1994, 56 : 143-56.
25. WHO. Biennial report: 1992-1994, WHO Geneva, 1994.