Line scan imaging of brain metabolites with CPMG sequences at 1.5 Tesla

Journal of Magnetic Resonance Imaging

Volumn 6, Issue 2, 1996, Pages 399-405

  Mulkern, Robert V ^a   Meng, Jiqun ^c   Oshio, Koichi ^b   Aria Tzika, A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c GE MEDICAL SYSTEMS   (United States)

Author keywords

Brain metabolites; CPMG; Quantitation; Spectroscopic imaging; T2 decay

Indexed keywords

DIAGNOSTIC AGENT;

ADOLESCENT; ADULT; ARTICLE; BRAIN; BRAIN LEVEL; BRAIN TUMOR; GLIOMA; HISTOLOGY; HUMAN; IMAGE PROCESSING; MALE; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ADOLESCENT; ADULT; BRAIN; BRAIN CHEMISTRY; BRAIN NEOPLASMS; GLIOMA; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE;

EID: 0030090104     PISSN: 10531807     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmri.1880060221     Document Type: Article

References (23)

1. Frahm J, Merboldt KD, Hanicke W. Localized proton spectroscopy using stimulated echoes. J Magn Reson 1987; 72:502-508.
2. Bottomley PA. Spatial localization in NMR spectroscopy in vivo. Ann NY Acad Sci 1987; 508:333-348.
3. Carr HY, Purcell EM. Effects of diffusion on free precession in nuclear magnetic resonance experiments. Phys Rev 1954; 94: 630-638.
4. Meiboom S, Gill D. Modified spin-echo method for measuring nuclear relaxation times. Rev Sci Instrum 1958; 29:688-691.
5. Mulkern RV, Melki PS, Lilly HS, Hoffer FA. 1D spectroscopic imaging with RF echo planar (SIRFEN) methods. Magn Reson Imaging 1991; 9:909-916.
6. Oshio K, Mulkern RV. Rapid fat/water assessment in knee cavity bone marrow by inner volume spectroscopic imaging with RARE. JMRI 1992; 2:601-604.
7. Mulkern RV, Meng J, Oshio K, Guttmann CRG, Jaramillo D. Bone marrow characterization in the lumbar spine with inner volume spectroscopic CPMG imaging studies. JMRI 1994; 4: 585-589.
8. Mulkern RV, Meng J, Oshio K, Williamson DS, Lilly HS, Guttmann CRG, Jaramillo D. Spectroscopic imaging of the knee with line scan CPMG sequences. J Comput Assist Tomogr 1995; 19:247-255.
9. Duyn JH, Moonen CTW. Fast proton spectroscopic imaging of human brain using multiple spin echoes. Magn Reson Med 1993; 30:409-414.
10. Duyn JH, Frank JA, Moonen CTW. Incorporation of lactate measurement in multi-spin-echo proton spectroscopic imaging. Magn Reson Med 1995; 33:101-107.
11. Shungu DC, Hilal SK. Multislice proton spectroscopic imaging of the brain with retention of spectral selectivity. In: Proceedings of the Society of Magnetic Resonance 1995. Nice, France: Society of Magnetic Resonance in Medicine, 1995; 329.
12. Singh S, Deslauriers R. Tailored selective NMR excitation by projection presaturation. Concepts Magn Reson 1995; 7:1-27.
13. Frahm J, Bruhn H, Gyngell ML, Merboldt KD, Hanicke W, Sauter R. Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites. Magn Reson Med 1989; 11:47-63.
14. Kreis R, Ernst T, Ross BD. Development of the human brain: In vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy. Magn Reson Med 1993; 30:424-437.
15. Webb PG, Sailasuta N, Kohler SJ, Raidy T, Moats RA, Hurd RE. Automated single-voxel proton MRS: Technical development and multisite variation. Magn Reson Med 1994; 31:365-373.
16. Alger JR, Frank JA, Bizzi A, Fulham MJ, DeSouza BX, Duhaney MO, Inscoe SW, Black JL, van Zijl PCM, Moonen CTW, Di Chiro G. Metabolism of human gliomas: assessment with H-1 MR spectroscopy and F-18 fluorodeoxyglucose PET. Radiology 1990; 177:633-641.
17. 1H NMR spectroscopic imaging. Magn Reson Med 1990; 13:62-76.
18. Barker PB, Glickson JD, Bryan RN. In vivo magnetic resonance spectroscopy of human brain tumors. Top Magn Reson Imaging 1993; 5:32-45.
19. Manton DJ, Lowry M, Blackband SJ, Horsman A. Quantitative proton MRS of brain tumors reveals increased choline T2 in meningiomas. MAGMA 1994; 2:361-363.
20. Barker PB, Breiter SN, Soher BJ, Chatham JC, Forder JR, Samphilipo MA, Magee CA, Anderson JH. Quantitative proton spectroscopy of canine brain: in vivo and In vitro correlations. Magn Reson Med 1994; 32:157-163.
21. 1H NMR spectroscopy in vivo and in vitro. J Comput Assist Tomogr 1994; 18: 705-713.
22. Kamada K, Houkin K, Hida K, Matsuzawa H, Iwasaki Y, Abe H, Nakada T. Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time. Magn Reson Med 1994; 31:537-540.
23. Henkelman RM, Watts JF, Kucharczyk W. High signal intensity in MR images of calcified brain tissue. Radiology 1991; 179: 199-206.