Immune evasion by Helicobocter pylori : Gastric spiral bacteria lack surface immunoglobulin deposition and reactivity with homologous antibodies

Helicobacter

Volumn 1, Issue 1, 1996, Pages 20-27

  Darwin, Peter E ^a,b   Sztein, Marcelo B ^a   Zheng, Qiao Xi ^a   James, Stephen P ^a   Fantry, George T ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Gastrointestinal Division   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL; ARTICLE; FLUORESCENT ANTIBODY TECHNIQUE; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; IMMUNOLOGY; MICROBIOLOGY; RABBIT; STOMACH ACID;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GASTRIC ACID; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; RABBITS; RECEPTORS, ANTIGEN, B-CELL;

EID: 0030089039     PISSN: 10834389     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-5378.1996.tb00004.x     Document Type: Article

References (16)

1. Rathbone BJ, Wyatt JI, Worsley BW, et al. Systemic and local antibody responses to gastric Campylobacter pyloridis in non-ulcer dyspepsia. Gut 1986;27:642-7.
2. Crabtree JE, Taylor JD, Wyatt JI, Heatley RV, Shallcross TM, Tompkins DS, Rathbone BJ. Mucosal IgA recognition of Helicobater pylori 120 kDa protein, peptic ulceraton, and gastric pathology. Lancet 1991;338:332-4.
3. Tosi MF, Czinn SJ. Opsonic activity of specific human IgG against Helicobacter pylori. J Infect Dis 1990;162;156-62.
4. Newell DG, Stacey AR. B cell responses in H. pylori infection. In: Hunt RH, Tytgat GNJ, eds. H. pylori - basic Mechanisms to Clinical Cure. Dordrecht: Kluwer Academic Publishers, 1994;309-20.
5. Cover TL, Dooley CP, Blaser MJ. Characterization of an human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity. Infect Immun 1990;58:603-10.
6. Cover TL, Cao P, Murthy UK, Sipple MS, Blaser MJ. Serum neutralizing antibody response to the vacuolating cytotoxin of Helicobacter pylori. J Clin Invest 1992;90:913-8.
7. Czinn SJ, Cai A, Nedrud JG. Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization. Vaccine 1993;11:637-42.
8. Michetti P, Corthesy-Theulaz I, Davin C, Haas R, Vaney AC, Heitz M, Bille J, Kraehenbuhl JP, Saraga E, Blum AL. Immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori urease. Gastroenterology 1994;107: 1002-11.
9. Marchetti M, Arico B, Burroni D, Figura N, Rappuoli R, Ghiara P. Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science 1995;267:1655-8.
10. Wyatt JI, Rathbone BJ, Heatley RV. Local immune response to gastric Campylobacter in non-ulcer dyspepsia. J Clin Pathol 1986;39:863-870.
11. Sciortino CV. An immunofluorescent stain for Helicobacter pylori. Hybridoma 1993;12:333-42.
12. Langdale-Brown Haqqani B, Haggani MT. Acridine orange fluorescence, Campylobacter pylori and chronic gastritis. Scand J Gastroenterol 1990;25:127-33.
13. Schnadig VJ, Bigio EH, Gourley WK, Stewart GD, Newton GA, Shabot JM. Identification of Campylobacter pylori by endoscopic brush cytology. Diagn Cytopathol 1990;6:227-34.
14. Xiang Z, Bugnoli M, Ponzetto A, Morando A, Figura N, Covacci A, Petracca R, Pennatini C, Censini S, Armellini D, Rappuoli R. Detection in an enzyme immunoassay of an immune response to a recombinant fragment of the 128 kilodalton protein (CagA) of Helicobacter pylori. Eur J Clin Microbiol Infect Dis 1993;12:739-45.
15. Crabtree JE, Shallcross TM, Wyatt JI, Taylor JD, Heatley RV, Rathbone BJ, Losowsky MS. Mucosal humoral immune response to Helicobacter pylori in patients with duodenitis. Dig Dis Sci 1991;36:1266-73.
16. Isaacson P. Immunoperoxidase study of the secretory immunoglobulin system and lysozyme in normal and diseased gastric mucosa. Gut 1982;28: 578-88.