Interleukin-1β decreases sensitivity of guinea-pig airway to potassium chloride and isoproterenol by an epithelium-dependent mechanism

Respirology

Volumn 1, Issue 1, 1996, Pages 61-67

  Munakata, Mitsuru ^a   Chen, Hang ^a   Nasuhara, Yasuyuki ^a   Sato, Atsuko ^a   Takahashi, Toru ^a   Sato, Rika ^a   Homma, Yukihiko ^a   Kawakami, Yoshikazu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Airway epithelium; Interleukin l ; Membrane potential; Prostaglandins; adrenergic receptor

Indexed keywords

BRONCHODILATING AGENT; INTERLEUKIN 1; ISOPRENALINE; POTASSIUM CHLORIDE;

ANIMAL; ARTICLE; DRUG EFFECT; EPITHELIUM; GUINEA PIG; MALE; PHYSIOLOGY; RESPIRATORY FUNCTION; RESPIRATORY SYSTEM;

ANIMALS; BRONCHODILATOR AGENTS; EPITHELIUM; GUINEA PIGS; INTERLEUKIN-1; ISOPROTERENOL; MALE; POTASSIUM CHLORIDE; RESPIRATORY PHYSIOLOGY; RESPIRATORY SYSTEM;

EID: 0030089014     PISSN: 13237799     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1843.1996.tb00012.x     Document Type: Article

References (8)

1. Balkwill FR, Burke F. The cytokine network. Immunology Today 1989; 10: 299-304.
2. Dinarello CA. The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome. J. Infect. Dis. 1991; 163: 1177-84.
3. Kelley J. Cytokines of the lung. Am. Rev. Resp. Dis. 1990; 141: 765-88.
4. Elias JA, Kotloff R, Ray P. Cytokines in pulmonary inflammation. In: AP Fishman (ed.), Update: Pulmonary Diseases and Disorders. New York: McGraw-Hill, 1992; 93-114.
5. Bentley AM, Menz G, Storz G et al. Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Am. Rev. Respir. Dis. 1992; 146: 500-6.
6. Hernandez A, Omini C, Daffonchio L. Interleiikin-1β: A possible mediator of lung inflammation and airway hyperreactivity. Pharmacol. Res. 1991; 24: 385-93.
7. Beasley D. Interleukin 1 and endotoxin activate soluble guanylate cyclase in vascular smooth muscle. Am. J. Physiol. 1990; 259: R38-44.
8. Dinarello CA. Interleukin-1. Rev. Infect. Dis. 1984; 6: 51-95.