Site-specific DNA substrates for human excision repair: Comparison between deoxyribose and base adducts

Chemistry and Biology

Volumn 3, Issue 2, 1996, Pages 121-128

  Hess, Martini ^a   Schwitter, Urs ^b   Petretta, Mario ^b   Giese, Bernd ^b   Naegeli, Hanspeter ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Bulky adduct; Damage recognition; DNA repair; Nucleotide excision repair

Indexed keywords

CIRCULAR DNA; DEOXYRIBOSE;

ARTICLE; COMPARATIVE STUDY; DNA ADDUCT; DNA REPAIR; ENZYME SPECIFICITY; HUMAN; METABOLISM; RESTRICTION MAPPING;

DEOXYRIBOSE; DNA ADDUCTS; DNA REPAIR; DNA, CIRCULAR; HUMANS; RESTRICTION MAPPING; SUBSTRATE SPECIFICITY;

EID: 0030087999     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(96)90288-4     Document Type: Article

References (13)

1. Friedberg, E.G., Walker, G.C. & Siede, W. (1995). DNA Repair and Mutagenesis. American Society for Microbiology, Washington D.C.
2. Hoeijmakers, J.H.J. (1993). Nucleotide excision repair ll: from yeast to mammals. Trends Genet. 9, 211-217.
3. Sancar, A. (1994). Mechanisms of DNA excision repair. Science 266, 1954-1956.
4. Tanaka, K. & Wood, R.D. (1994). Xeroderma pigmentosum and nucleotide excision repair of DNA. Trends Biochem. Sci. 19, 83-86.
5. Huang, J.-C, Svoboda, D.L., Reardon, J.T. & Sancar, A. (1992). Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5′ and the 6th phosphodiester bond 3′ to the photodimer. Proc. Natl. Acad. Sci. USA 89, 3664-3668.
6. Hansson, J., Munn, M., Rupp, W.D., Kahn, R. & Wood, R.D. (1989). Localization of DNA repair synthesis by human cell extracts to a short region at the site of a lesion. J. Biol. Chem. 264, 21788-21792.
7. Hoeijmakers, J.H.J. (1994). Human nucleotide excision repair syndromes: molecular clues to unexpected intricacies. Fur. J. Cancer 30A, 1912-1921.
8. Wood, R.D., Robins, P. & Lindahl, T. (1988). Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts. Cell 53, 97-106.
9. Sibghat-UIIah, Husain, I., Carlton, W. & Sancar, A. (1989). Human nucleotide excision repair in vitro: repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extracts. Nucleic Acids Res. 17, 4471-4484.
10. Huang, J.-C, Hsu, D.S., Kazantsev, A. & Sancar, A. (1994). Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts. Proc. Natl. Acad. Sci. USA 91, 12213-12217.
11. Wood, R.D. & Coverley, D. (1991). DNA excision repair in mammalian cell extracts. Bioessays 13, 447-453.
12. Dianov, G., Price, A. & Lindahl, T. (1992). Generation of singlenucleotide repair patches following excision of uracil residues from DNA. Mol. Cell. Biol. 12, 1605-1612.
13. Matsunaga, T., Mu, M., Park, C-H., Reardon, J.T. & Sancar, A. (1995). Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies. J. Biol. Chem. 270, 20862-20869.