Nonpeptide endothelin receptor antagonists. VI: Pharmacological characterization of SB 217242, a potent and highly bioavailable endothelin receptor antagonist

Journal of Pharmacology and Experimental Therapeutics

Volumn 276, Issue 2, 1996, Pages 609-615

  Ohlstein, Eliot H ^a   Nambi, Ponnal ^a   Lago, Amparo ^b   Hay, Douglas W P ^a   Beck, George ^a   Fong, Kei Lai ^a   Eddy, E Priya ^a   Smith, Philip ^a   Ellens, Harma ^a   Elliott, John D ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID; ENDOTHELIN; ENDOTHELIN RECEPTOR; ENRASENTAN; INDAN DERIVATIVE;

ANIMAL; ARTICLE; BIOAVAILABILITY; CELL STRAIN CACO 2; CHO CELL; DRUG ANTAGONISM; DRUG EFFECT; HAMSTER; HEMODYNAMICS; HUMAN; IN VITRO STUDY; MALE; METABOLISM; PERMEABILITY; RABBIT; RAT; SPRAGUE DAWLEY RAT; VASOCONSTRICTION;

ANIMALS; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CARBOXYLIC ACIDS; CHO CELLS; CRICETINAE; ENDOTHELINS; HEMODYNAMIC PROCESSES; HUMANS; INDANS; MALE; PERMEABILITY; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ENDOTHELIN; VASOCONSTRICTION;

EID: 0030077787     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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