Molecular modelling and conformational analysis of a GABAB antagonist

Journal of Computer-Aided Molecular Design

Volumn 10, Issue 1, 1996, Pages 31-40

  Pirard, Bernard ^a   Durant, François ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

Author keywords

Crystallographic database; Molecular dynamics; Pharmacophoric pattern; Similarity

Indexed keywords

DATABASE SYSTEMS;

CONFORMATIONAL ANALYSIS; CONFORMATIONAL PREFERENCES; CONFORMATIONAL SPACE; CRYSTALLOGRAPHIC DATABASE; DYNAMICS SIMULATION; MOLECULAR MODELING ANALYSIS; PHARMACOPHORIC PATTERN; SIMILARITY;

MOLECULAR DYNAMICS;

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; BACLOFEN; DRUG DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; CONFORMATION; CRYSTALLOGRAPHY; DRUG ANTAGONISM; FACTUAL DATABASE; THERMODYNAMICS;

BACLOFEN; COMPUTER SIMULATION; CRYSTALLOGRAPHY; DATABASES, FACTUAL; GABA AGONISTS; GABA ANTAGONISTS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RECEPTORS, GABA-B; THERMODYNAMICS;

EID: 0030076993     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00124463     Document Type: Article

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