Inhibition of ligand induced promoter occupancy in vivo by a dominant negative RXR

Genes to Cells

Volumn 1, Issue 2, 1996, Pages 209-221

  Blanco, Jorge C G ^a   Dey, Anup ^a   Leid, Mark ^a   Minucci, Saverio ^a   Park, Byung Kiu ^a   Jurutka, Peter W ^a   Haussler, Mark R ^a   Ozato, Keiko ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL RECEPTOR; DNA BINDING PROTEIN; LIGAND; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; TRANSCRIPTION FACTOR; VITAMIN D;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL CULTURE; DNA FOOTPRINTING; DNA METHYLATION; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOUSE; PROMOTER REGION; PROTEIN BINDING; REPORTER GENE;

ANIMALS; DNA FOOTPRINTING; DNA METHYLATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; LIGANDS; MICE; MODELS, GENETIC; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTORS, CALCITRIOL; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; SEQUENCE DELETION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRETINOIN; TUMOR CELLS, CULTURED; VITAMIN D;

EID: 0030072614     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1996.d01-229.x     Document Type: Article

References (5)

1. Baniahmad, A., Kohne, A.C. & R. Renkawitz, R. (1992) A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor. EMBO J. 11, 1015-1023.
2. Baniahmad, A., Leng, X., Burris, T.P., Tsai, S.Y., Tsai, M-J. & O'Malley, B. (1995) The T-4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol. Cell. Biol. 15, 76-86.
3. Barettino, D., Vivanco Ruiz, M.d.M. & Stunnenberg, H.G. (1994) Characterization of the ligand dependent transactivation domain of the thyroid hormone receptor. EMBO J. 13, 3039-3049.
4. Blanco, J.C.G., I-M. Wang, I-M., Tsai, S.Y., Tsai, M-J., O'Malley, B.W., Jurutka, P.W., Haussler, R. & Ozato, K. (1995) Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription. Proc. Natl Acad. Sci. USA 92, 1535-1539.
5. Breen, E.C., van Wijnen, A.J., Lian, J.B., Stein, G.S. & Stein, J. (1994) In vivo occupancy of the vitamin D responsive element in the osteocalcin gene supports vitamin D-dependent transcriptional upregulation in intact cells. Proc. Natl Acad. Sci. USA 91, 12902-12906.