A gene replacement strategy for engineering nisin

Microbiology

Volumn 142, Issue 1, 1996, Pages 47-55

  Dodd, Helen M ^a   Horn, Nikki ^a   Giffard, Catriona J ^b   Gasson, Michael J ^a  

^a INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

Author keywords

Antimicrobial peptide; Gene replacement; Lactococcus lactis; Nisin; Protein engineering

Indexed keywords

LANTIBIOTIC; NISIN;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; EXPRESSION VECTOR; GENE MUTATION; GENETIC ENGINEERING; GENETIC SELECTION; LACTOCOCCUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

EID: 0030071838     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/13500872-142-1-47     Document Type: Article

References (31)

1. Biswas, I., Gruss, A., Ehrlich, S. D. & Maguin, E. (1993). High-efficiency gene inactivation and replacement system for gram-positive bacteria. J Bacteriol 175, 3628-3635.
2. Casadaban, M. J. & Cohen, S. N. (1980). Analysis of gene control signals by DNA fusion and cloning in Escherichia coli. J Mol Biol 138, 179-207.
3. - cloning vectors. I. Improved pUC polylinker regions to facilitate the use of sonicated DNA for nucleotide sequencing. Gene 68, 139-149.
4. Chan, W. C., Bycroft, B. W., Lian, L.-Y. & Roberts, G. C. K. (1989). Isolation and characterization of two degradation products derived from the peptide antibiotic nisin. FEBS Lett 252, 29-36.
5. Chopin, M.-C., Chopin, A., Rouault, A. & Galleron, N. (1989). Insertion and amplification of foreign genes in the Loctococcus lactis subsp. lactis chromosome. Appl Environ Microbiol 55, 1769-1774.
6. Dodd, H. M. & Gasson, M. J. (1994). Bacteriocins of lactic acid bacteria. In Genetics and Biotechnology of Lactic Acid Bacteria, pp. 211-251. Edited by M. J. Gasson & W. M. de Vos. Glasgow: Blackie Academic & Professional.
7. Dodd, H. M., Horn, N. & Gasson, M. J. (1990). Analysis of the genetic determinant for the peptide antibiotic nisin. J Gen Microbiol 136, 555-566.
8. Dodd, H. M., Horn, N., Zhang, H. & Gasson, M. J. (1992). A lactococcal expression system for engineered nisins. Appl Environ Microbiol 58, 3683-3693.
9. Dodd, H. M., Horn, K. & Gasson, M. J. (1995). A cassette vector for protein engineering the lantibiotic nisin. Gene 162, 163-164.
10. Engelke, G., Gutowski-Eckel, Z., Kiesau, P., Siegers, K., Hammelmann, M. & Entian, K.-D. (1994). Regulation of nisin biosynthesis and immunity in Lactococcus lactis 6F3. Appl Environ Microbiol 60, 814-825.
11. Gasson, M. J. (1983). Plasmid components of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing. J Bacteriol 154, 1-9.
12. Holo, H. & Nes, I. F. (1989). High-frequency transformation by electroporation of Lactococcus lactis subsp. cremoris grown with glycine in osmotically stabilized media. Appl Environ Microbiol 55, 3119-3123.
13. Horn, N., Swindell, S. R., Dodd, H. M. & Gasson, M. J. (1991). Nisin biosynthesis genes are encoded by a novel conjugative transposon. Mol & Gen Genet 228, 129-135.
14. Klein, C. & Entian, K.-D. (1994). Genes involved in self-protection against the lantibiotic subtilin produced by Bacillus subtilis ATCC 6633. Appl Environ Microbiol 60, 2793-2801.
15. Klein, C., Kaletta, C., Schnell, N. & Entian, K.-D. (1992). Analysis of genes involved in biosynthesis of the lantibiotic subtilin. Appl Environ Microbiol 58, 132-142.
16. Klein, C., Kaletta, C. & Entian, K.-D. (1993). Biosynthesis of the lantibiotic subtilin is regulated by a histidine kinase/response regulator system. Appl Environ Microbiol 59, 296-303.
17. Kuipers, O. P., Rollema, H. S., Yap, W. M. G. J., Boot, H. J., Siezen, R. J. & de Vos, W. M. (1992). Engineering dehydrated amino acid residues in the antimicrobial peptide nisin. J Biol Chem 267, 24340-24346.
18. Kuipers, O. P., Beerthuyzen, M. M., Siezen, R. J. & de Vos, W. M. (1993). Characterization of the nisin gene cluster msABTCIPR of Lactococcus lactis. Eur J Biochem 216, 281-291.
19. Kuipers, O. P., Beerthuyzen, M. M., De Ruyter, P. G. G. A., Luesink, E. J. & de Vos, W. M. (1995). Autoregulation of nisin biosynthesis in Lactococcus lactis by signal transduction. J Biol Chem (in press).
20. Leenhouts, K. J., Kok, J. & Venema, G. (1989). Campbell-like integration of heterologous plasmid DNA into the chromosome of Lactococcus lactis subsp. lactis Appl Environ Microbiol 55, 394-400.
21. Leenhouts, K. J., Kok, J. & Venema, G. (1990). Stability of integrated plasmids in the chromosome of Lactococcus lactis. Appl Environ Microbiol 56, 2726-2735.
22. Lennox, E. S. (1955). Transduction of linked genetic characters of the host bacteriophage P1. Virology 1, 190-206.
23. Liu, W. & Hansen, J. N. (1992). Enhancement of the chemical and antimicrobial properties of subtilin by site-directed mutagenesis. J Biol Chem 267, 25078-25085.
24. Liu, W. & Hansen, J. N. (1993). The antimicrobial effect of a structural variant of subtilin against outgrowing Bacillus cereus T spores and vegetative cells occurs by different mechanisms. Appl Environ Microbiol 59, 648-651.
25. Mulders, J. W. M., Boerrigter, I. J., Rollema, H. S., Siezen, R. J. & de Vos, W. M. (1991). Identification and characterization of the lantibiotic nisin Z, a natural nisin variant. Eur J Biochem 201, 581-584.
26. Rauch, P. J. G., Kuipers, O. P., Siezen, R. J. & de Vos, W. M. (1994). Genetics and protein engineering of nisin. In Bacteriocins of Lactic Acid Bacteria, pp. 223-250. Edited by L. De Vuyst & E. J. Vandamme. Glasgow: Blackie Academic & Professional.
27. Rollema, H. S., Kuipers, O. P., Both, P., de Vos, W. M. & Siezen, R. J. (1995). Improvement of solubility and stability of the antimicrobial peptide nisin by protein engineering. Appl Environ Microbiol 61, 2873-2878.
28. Siegers, K. & Entian, K.-D. (1995). Genes involved in immunity to the lantibiotic nisin produced by Lactococcus lactis 6F3. Appl Environ Microbiol 61, 1082-1089.
29. Terzaghi, B. E. & Sandine, W. E. (1975). Improved medium for lactic streptococci and their bacteriophages. Appl Microbiol 29, 807-813.
30. de Vos, W. M., Jung, G. & Sahl, H.-G. (1991). Definitions and nomenclature of lantibiotics. In Nisin and Novel Lantibiotics, pp. 457-463. Edited by G. Jung & H.-G. Sahl. Leiden: ESCOM.
31. de Vos, W. M., Beerthuyzen, M. M., De Ruyter, P., Luesink, E. & Kuipers, O. P. (1994). Control of nisin gene expression system. Proceedings of the 2nd International Workshop on Lantibiotics, Papendal, The Netherlands.