Cerebrospinal fluid ceftazidime kinetics in patients with external ventriculostomies

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 3, 1996, Pages 763-766

  Nau, R ^a   Prange, H W ^a   Kinzig, M ^b   Frank, A ^b   Dressel, A ^a   Scholz, P ^a   Kolenda, H ^a   Sorgel, F ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b Institute for Biomedical Research   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; CATECHOLAMINE; CEFTAZIDIME; CEFTRIAXONE; DEXAMETHASONE; HISTAMINE H2 RECEPTOR ANTAGONIST; SEDATIVE AGENT; SORBITOL;

ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL MENINGITIS; BLOOD CEREBROSPINAL FLUID BARRIER; CEREBROSPINAL FLUID SHUNTING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG CEREBROSPINAL FLUID LEVEL; DRUG PENETRATION; FEMALE; HUMAN; HYDROCEPHALUS; INTRAVENOUS DRUG ADMINISTRATION; MALE; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

EID: 0030071460     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.3.763     Document Type: Article

References (20)

1. Alestig, K., L. Olaison, and M. Rylander. 1985. Ceftazidime for Pseudomonas meningitis. Lancet i:161-162.
2. Cherubin, C. E., R. H. K. Eng, R. Norrby, J. Modai, G. Humbert, and G. Overturf. 1989. Penetration of newer cephalosporins into cerebrospinal fluid. Rev. Infect. Dis. 11:525-548.
3. Drusano, G. L. 1988. Role of pharmacokinetics in the outcome of infections Antimicrob Agents Chemother. 32:289-297.
4. Drusano, G. L., H. C. Standiford, B. Fitzpatrick, J. Leslie, P. Tangtatsawassdi, P. Ryan, B. Tatem, M. R. Moody, and S. C. Schimpff. 1984. Comparison of the pharmacokinetics. of ceftazidime and moxalactam and their microbiological correlates in volunteers. Antimicrob. Agents Chemother. 26:388-393.
5. Emmerson, A. M., P. A. Lamport, D. S. Reeves, M. J. Bywater, H. A. Holt, R. Wise, J. Andrews, and M. J. Hall. 1985. The in vitro antibacterial activity of ceftriaxone in comparison with nine other antibiotics. Curr Med. Res. Opin 9:480-493.
6. Fishbein, D. B., D. L. Palmer, K. M. Porter, and W. P. Reed. 1981. Bacterial meningitis in the absence of CSF pleocytosis. Arch. Intern. Med. 141:1369-1372
7. Fong, I. W., and K. B. Tomkins. 1985. Review of Pseudomonas aeruginosa meningitis with special emphasis on treatment with ceftazidime. Rev Infect Dis. 5:604-612
8. Hatch, D., G. D. Overturf, A. Kovacs, D. Forthal, and C. Leong. 1988 Treatment of bacterial meningitis with ceftazidime. Pediatr. Infect. Dis. 5: 416-420.
9. Lüthy, R., J. Blaser, A. Bonetti, H. Simmen, R. Wise, and W. Siegenthaler. 1981 Comparative multiple-dose pharmacokinetics of cefotaxime, moxalactam, and ceftazidime Antimicrob. Agents Chemother. 20:567-575.
10. Moore, C. M., and M. Ross. 1973. Acute bacterial meningitis with absent or minimal cerebrospinal fluid abnormalities Clin. Pediatr. 12:117-118.
11. Nau, R., H. W. Prange, P. Muth, G. Mahr, S. Menck, H. Kolenda, and F. Sörgel. 1993. Passage of cefotaxime and ceftriaxone into cerebrospinal fluid of patients with uninflamed meninges. Antimicrob. Agents Chemother 37: 1518-1524.
12. Nau, R., F. Sörgel, and H. W. Prange. 1994. Lipophilicity at pH 7.4 and molecular size govern the entry of not actively transported drugs into the cerebrospinal fluid in humans with uninflamed meninges. J Neurol. Sci. 122: 61-65.
13. Nau, R., G. Zysk, A. Thiel, and H. W. Prange. 1993. Pharmacokinetic quantification of the exchange of drugs between blood and cerebrospinal fluid in man Eur J. Clin Pharmacol. 45:469-475
14. Noltinog, A., and H. Derendorf. 1994. Pharmacokinetic profile: ceftazidime Antiinfect. Drugs Chemother. 12:31-35
15. Norrby, S. R. 1985. Role of cephalosporins in the treatment of bacterial meningitis in adults. Overview with special emphasis on ceftazidime Am J Med 79:56-61
16. Powers, W. J. 1985. Cerebrospinal fluid lymphocytosis in acute bacterial meningitis. Am. J. Med. 79:216-220.
17. Scheld, W. M., J. P. Brodeur, J. M. Keeley, M. R. Field, W. J. Kelly, W. J. Long, and O. Zak. 1984. Evaluation of azlocillin in vitro and in discriminative animal models of infection J Antimicrob. Chemother. 11(Suppl. B):51-68
18. Täuber, M. G., C. A. Doroshow, C. J. Hackbarth, M. G. Rusnak, T. A. Drake, and M. A. Sande. 1984. Antibacterial activity of β-lactam antibiotics in experimental meningitis due to Streptococcus pneumoniae. J. Infect. Dis. 149:568-574.
19. Tunkel, A. R., B. Wispelwey, and W. M. Scheld. 1990. Bacterial meningitis. Recent advances in pathophysiology and treatment. Ann Intern. Med. 112: 610-623.
20. Walstad, R. A., K. B. Hellum, S. Bilka, L. G. Bilka. T. Frederiksen, K. I. Myhre, and G. R. Spencer. 1983. Pharmacokinetics and tissue penetration of ceftazidime: studies on lymph, aqueous humour, skin blister, cerebrospinal and pleural fluid. J. Antimicrob. Chemother. 12(Suppl A):275-282