Thrombin-antithrombin III complexes as an additional diagnostic aid in pulmonary embolism

Pathophysiology of Haemostasis and Thrombosis

Volumn 26, Issue 1, 1996, Pages 16-22

  Carmassi, Franco ^a   Morale, Marco ^a   Negri, Ferdinando De ^a   Puccetti, Renzo ^a   Pistelli, Francesco ^a   Mariani, Giuliano ^a   Pazzagli, Marcello ^a   Palla, Antonio ^a   Giuntini, Carlo ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Antithrombin III; Blood coagulation tests; Diagnostic tests; Pulmonary embolism; Thrombin; Thrombin antithrombin III complexes

Indexed keywords

ANTITHROMBIN III; THROMBIN;

ADULT; AGED; ARTICLE; BLOOD CLOTTING TEST; CONTROLLED STUDY; FEMALE; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; ANTITHROMBIN III; BLOOD COAGULATION TESTS; EVALUATION STUDIES; FEMALE; FIBRINOLYSIS; HUMANS; MALE; MIDDLE AGED; PEPTIDE HYDROLASES; PREDICTIVE VALUE OF TESTS; PULMONARY EMBOLISM;

EID: 0030071068     PISSN: 14248832     EISSN: 14248840     Source Type: Journal    
DOI: 10.1159/000217183     Document Type: Article

References (31)

1. Bell WR, Simon TL: Current status of pulmonary thromboembolic disease: Pathophysiology, diagnosis, prevention and treatment. Am Heart J 1982;103:239-262.
2. Sandler DA, Martin JF: Autopsy proven pulmonary embolism in hospital patients: Are we detecting enough deep vein thrombosis? J R SocMed 1989;82:203-205.
3. Goldhaber SZ: Strategies for diagnosis; in Goldhaber SZ (ed): Pulmonary embolism and deep vein thrombosis. Philadelphia, Saunders, 1985, pp 79-97.
4. Dalcn JE, Alpert JS: Natural history of pulmonary embolism. Progr Car-diovascDis 1974;17:259-270.
5. Nielsen HK: Pathophysiology of venous thromboembolism. Semin Thromb Hemost 1991; 17:(suppl 3): 250-253.
6. Sasahara AA, Sidd JJ. Tremblay G: Cardiopulmonary consequences of acute pulmonary embolism disease. Progr Cardiovasc Dis 1966:9:259-274.
7. Celi A, Palla A, Petruzzelli S, Car-rozzi L, Jacobson A, Celia G, Giun-tini C, Sasahara AA: Prospective study of a standardized questionnaire to improve clinical estimate of pulmonary embolism. Chest 1989; 95:332-337.
8. Predilctto R, Paoletti P, Fornai E, Perissinotto A, Petruzzelli S, Giun-tini C: Natural course of treated pulmonary embolism. Evaluation by perfusion lung scintigraphy, gas exchange, and chest roentgenogram. Chest 1990;97:554-561.
9. Palla A, Petruzzelli S, Donnamaria V, Rossi G, Maltinti G, Giuntini C: Radiographic assessment of perfusion impairment in pulmonary embolism. Europ J Radiol 1985;5:252-255.
10. Goldhaber SZ, Vaughan DE, Tu-meh SS, Loscalzo J: Utility of cross-linked fibrin degradation products in the diagnosis of pulmonary embolism. Am Heart J 1988; 116:505-508.
11. Rowbotham BJ. Egerton-Vemon J. Whitaker AN, Elms MJ. Buncc 1H: Plasma cross-linked fibrin degradation products in pulmonary embolism. Thorax 1990;45:684-687.
12. Bounamcaux H, Cirafici P, de Moerloose P, Schneider PA, Slos-man D, Reber G, Unger PF: Measurement of D-dimer in plasma as diagnostic aid in suspected pulmonary embolism. Lancet 1991;337: 196-200.
13. Leitha T, Speiser W, Dudczak R: Pulmonary embolism: Efficacy of D-dimer and thrombin-antithrom-bin III complex determinations as screening tests before lung scanning. Chest 1991;100:1536-1541.
14. Mays EE: An arterial blood gas diagram for clinical use. Chest 1973;63: 793-800.
15. Allescia G, Di Ricco G, Formichi B, Marini C, Miniati M, Pistolesi M, Prediletto R, Sostman HD: Invasive and noninvasive diagnosis of pulmonary embolism: Preliminary results of a prospective study of the diagnosis of acute pulmonary embolism (Pisa-PED). J Nucl Biol Med 1994;38:131.
16. Pelzer H, Fuhge P, Bleyl H, Hcin-burger N: Enzyme immunoassay for determination of human thrombin-antithrombin III complex. Thromb Haemost 1985;P 142:24.
17. Kolde HJ: Chromotime system-A new generation of coagulation analyses. Behring Inst Mitt 1985;78: 176-187.
18. Dalcn JE, Benotti JR, Pratter MR: Pulmonary embolism. Curr Pul-monol 1982;4:43-65.
19. PIOPED Investigators. Value of ventilation-perfusion scan in acute pulmonary embolism. Results of the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED). JAMA 1990,263:2753-2759.
20. Speiser W, Letha T, Dudczak R, Lechner K: Plasma D-dimer and pulmonary embolism. Lancet 1989; i:792.
21. Juhan-Vague I, Aillaud MF, De Cock F: The fast-acting inhibitor of tissue-type plasminogen activator is an acute phase reactant protein; in Davidson JF, Donati MB, Coccheri S (eds): Progress in Fibrinolysis. Edinburgh, Churchill Livingstone, 1985, vol 7, pp 146-149.
22. Doolittle RF: Fibrinogen and fibrin; in Putnam FW (ed): The plasma proteins. New York, Academic Press, ed 2,1975, vol 2, p 110.
23. Speiser W, Mallek R, Koppensteiner R, Stumpflen A, Kapiotis S, Minar E, Ehringhcr H, Lechner K: D-dimer and TAT measurements in patients with deep vein thrombosis: Utility in diagnosis and judgement of anticoagulant in treatment effectiveness. Thromb Haemost 1990; 64:196-201.
24. Tabernero MD, Estellés A, Vicente V, Alberca I, Aznar J: Incidence of increased plasminogen activator inhibitor in patients with deep vein thrombosis and/or pulmonary embolism. Thromb Res 1989;56:565-570.
25. Teitel JM, Bauer KA, Lau HK, Rosenberg RD: Studies on the prothrombin activation pathway utilizing radioimmunoassays for the F2/ Fj+2 fragment and thrombin antithrombin complex. Blood 1982;59: 1086-1097.
26. Iwade K, Aosaki M, Ohki K, Hokari T, Kawana M, Hosoda S: Changes of coagulation and fibrinolytic activity in unstable angina (abstract). Thromb Haemost 1991;65:1094.
27. Gulba DC, Barthels M, Reil GH, Lichten PR: Thrombin-antithrom-bin III complex level as early predictor of reocclusion after successful thrombolysis. Lancet 1988;ii:97.
28. Blanke H, Praetorius G, Lechke M, Seitz R, Egbring R, Strauer BE: Diagnostic value of thrombin-anti-thrombin III complex in pulmonary embolism and in deep vein thrombosis: Comparison with fibrinopep-tide A, platelet factor 4 and p-throm-boglobulin. Klin Wochenschr 1987; 65:757-763.
29. Demers C, Ginsberg JS, Johnston M, Brill-Edwards P, Panju A: Thrombin-antithrombin III (TAT) complexes in pulmonary embolism (PE) (abstract). Thromb Haemost 1991;65:980.
30. Paltiel O: Epidemiology of venous tromboembolism; in Ledere JR (ed): Venous Thomboembolic Disorders. Philadelphia, Lea & Febiger, 1991.
31. Kaplan JE, Malik AB: Thrombin-induced intravascular coagulation: Role in vascular injury. Semin Thromb Hemost 1987;13:398-415.