Astrocytes and the delivery of glucose from plasma to neurons

Neurochemistry International

Volumn 28, Issue 3, 1996, Pages 231-241

  Forsyth, R J ^a  

^a Sir James Spence Institute   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGLUCOSE; GLUCOSE; GLYCOGEN;

ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN METABOLISM; CONTROLLED STUDY; EXTRACELLULAR FLUID; GLIA; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOGENOLYSIS; KINETICS; METABOLIC RATE; MICRODIALYSIS; NERVE CONDUCTION; NEUROANATOMY; PRIORITY JOURNAL;

INVERTEBRATA;

EID: 0030071024     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-0186(95)00094-1     Document Type: Note

References (47)

1. Blomqvist G., Gjedde A., Gutniak M., Grill V., Widén L., Stone-Elander S. and Hellstrand E. (1991) Facilitated transport of glucose from blood to brain in man and the effect of moderate hypoglycaemia on cerebral glucose utilization. Eur. J. Nucl. Med. 18, 834-837.
2. Cremer J. E., Cunningham V. J., Pardridge W. M., Braun L. D. and Olendorf W. H. (1979) Kinetics of blood-brain barrier transport of pyruvate, lactate and glucose in suckling, weaning and adult rats. J. Neurochem. 33, 439-445.
3. 31P nuclear magnetic resonance spectroscopy. Science 228, 1329-1331.
4. Dringen R., Gebhardt R. and Hamprecht B. (1993) Glycogen in astrocytes - possible function as lactate supply for neighbouring cells. Brain Res. 623, 208-214.
5. Eyre J. A., Stuart A. G., Forsyth R. J., Heaviside R. J. and Bartlett K. (1994) Glucose export from the brain in man : evidence for a role for astrocytic glycogen as a reservoir of glucose for neural metabolism. Brain Res. 635, 349-352.
6. Fellows L. K. and Boutelle M. G. (1993a) Rapid changes in extracellular glucose levels and blood flow in the stratum of the freely moving rat. Brain Res. 604, 225-231.
7. Fellows L. K., Boutelle M. G. and Fillenz M. (1993b) Physiological stimulation increases nonoxidative glucose metabolism in the brain of the freely moving rat. J. Neurochem. 60, 1258-1263.
8. Fellows L. K., Boutelle M. G. and Fillenz M. (1992) Extra-cellular brain glucose levels reflect local neuronal activity : a microdialysis study in awake, freely moving rats. J. Neurochem. 59, 2141-2147.
9. Forsyth R. J., Bartlett K., Burchell A., Scott H. M. and Eyre J. A. (1993) Astrocytic glucose-6-phosphatase and the permeability of brain microsomes to glucose-6-phosphate. Biochem. J. 294, 145-151.
10. Forsyth R. J., Bartlett K. and Eyre J. (1996) Dephosphorylation of 2-deoxyglucose 6-phosphate and 2-deoxyglucose export from cultured astrocytes. Neurochem. Int. 28, 243-250.
11. Fox P. T. and Raichle M. E. (1986) Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc. Natl Acad. Sci. U.S.A. 83, 1140-1144.
12. Fox P. T., Raichle M. E., Mintun M. A. and Dence C. (1988) Non-oxidative glucose consumption during focal physiologic neural activity. Science 241, 462-464.
13. Gerhart D. Z., Broderius M. A., Borson N. D. and Drewes L. R. (1992) Neurons and microvessels express the brain glucose transporter protein GLUT3, Proc. Natl Acad. Sci. U.S.A. 89, 733-737.
14. Guseinov T. Y. (1991) Carbohydrate metabolism of the brain in hypoxia [in Russian]. Anesteziol. Reanimat. 3, 14-17.
15. Huang S.-C., Phelps M. E., Hoffman E. J., Siden's K., Selin C. J. and Kuhl D. (1980) Noninvasive determination of local cerebral metabolic rate of glucose in man. Am. J. Physiol. 238, E68-E82.
16. Ignacio P. C., Baldwin B. A., Vijayan V. K., Tait R. C. and Gorin F. A. (1990) Brain isoenzyme of glycogen phosphorylase : immunohistological localization within the central nervous system. Brain Res. 529, 42-49.
17. Korf J., de Boer J., Postema F., Veneman K., and Flentge F. (1991) On-line real-time monitoring of extracellular lactate, ethanol, glucose and choline using microdialysis and enzyme reactors, in Microdialysis in the Neurosciences (Robinson T. E. and Justice J. B. Jr, eds), pp. 349-368. Elsevier, Amsterdam.
18. Kosaka T. and Hama K. (1986) Three-dimensional structure of astrocyles in the rat dentate gyrus. J. Comp. Neurol. 249, 242-260.
19. Kuffler S. W. and Nicholls J. G. (1966) (eds) The physiology of neuroglial cells. In Ergebnisse der Physiologie, biologischen Chemie und experimentellen Pharmakologie, pp. 1-91. Springer Verlag, Berlin.
20. Landis D. M. D. (1986) Membrane structure in astrocytes: In Cell Biology and Pathology of Astrocytes (Fedoroff S. and Vernadakis A., eds), pp. 61-76. Academic Press. London.
21. Lund-Andersen H. (1979) Transport of glucose from blood to brain. Physiol. Rev. 59, 305-352.
22. Magistretti P. J. (1991) Actions of neurotransmitters on non-neuronal cells as evidence for the existence of intrinsic neuronal circuits controlling local energy metabolism and cellular homeostasis within the central nervous system : In Brain Work and Mental Activity (Lassen N. A., Ingvar D. H., Raichle M. E. and Friberg L. eds), pp. 94-107. Munksgaard, Copenhagen.
23. Magistretti P. J., Sorg O. and Martin J.-L. (1993) Regulation of glycogen metabolism in astrocytes : physiological, pharmacological and pathological aspects. In Astrocytes : Pharmacology and Function (Murphy S., ed.), pp. 243-265. Academic Press Inc., San Diego.
24. Mata M., Fink D. J., Gainer H., Smith C. B., Davidsen L., Savaki H., Schwartz W. J. and Sokoloff L. (1980) Activity-dependent energy metabolism in rat posterior pituitary primarily reflects sodium pump activity. J. Neurochem. 34, 213-215.
25. Maxwell K., Berliner J. A. and Cancilla P. A. (1989) Stimulation of glucose analogue uptake by cerebral microvessel endothelial cells by a product released by astrocytes. J. Neuropath. Exp. Neurol. 48, 69-80.
26. Narlieva N. (1988) Multilamellar glial envelopes of synapses in the pontine nuclei of the cat. Acta Anal. 131, 227-230.
27. Nehlig A., de Vasconcelos A. P. and Boyet S. (1988) Quantitative autoradiographic measurement of local cerebral glucose utilization in freely moving rats during postnatal development. J. Neurosci. 8, 2321-2333.
28. Nelson T., Lucignani G., Goochee J., Crane A. M. and Sokoloff L. (1986) Invalidity of criticisms of the deoxyglucose method based on alleged glucose-6-phosphatase activity in brain. J. Neurochem. 46, 905-919.
29. Pellerin L. and Magistretti P. (1994) Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl Acad. Sci. U.S.A. 91, 10,625-10,629.
30. Pentreath V. W., Radojic T., Seal L. H. and Winstanley E. K. (1985) The glial cells and glia-neuron relations in the buccal ganglia of Planorbis corneus (L.): cytological, qualitative and quantitative changes during growth and aging. Phil. Trans. R. Soc. Lond. B 307, 399-455.
31. Phelps C. H. (1972) Barbiturate-induced glycogen accumulation in brain. An electron microscopic study. Brain Res. 39, 225-234.
32. 3H]2-deoxy-D-glucose in a mammalian retina. Neurosci. Lett. 122, 241-244.
33. Poitryyamate C. L., Poitry S. and Tsacopoulos M. (1995) Lactate released by Müller glial cells is a substrate for photoreceptors in mammalian retina [meeting abstract]. Inv. Ophth. Vis. Sci. 36, S126.
34. 1H NMR in human visual cortex during physiologic stimulation. Proc. Natl Acad. Sci. U.S.A. 88, 5829-5831.
35. Sacks W., Sacks S. and Fleischer A. (1983) A comparison of the cerebral uptake and metabolism of labelled glucose and deoxyglucose in vivo in rats. Neurochem. Res. 8, 661-685.
36. 14C]deoxyglucose method to incorporate effects of intracellular compartmentation in brain. J. Cereb. Blood Flow Metab. 9, 290-303.
37. Shank R. P. and Campbell G. L. (1984) α-Ketoglutarate and malate uptake and metabolism by synaptosomes : further evidence for an astrocyte-to-neuron metabolic shuffle. J. Neurochem. 43, 1153-1161.
38. Sokoloff L. (1977) Relation between physiological function and energy metabolism in the central nervous system. J. Neurochem. 29, 13-26.
39. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28, 897-916.
40. Swanson R. A. (1992) Physiologic coupling of glial glycogen metabolism to neuronal activity in brain. Can. J. Physiol. Pharmac. 70, S138-S144.
41. Swanson R. A. and Choi D. W. (1993) Glial glycogen stores affect neuronal survival during glucose deprivation in vitro. J. Cereb. Blood Flow Metab. 13, 162-169.
42. Tsacopoulos M. and Poitryyamate C. L. (1993) Cellular and molecular aspects of glial-neuron interactions in the retina. Neuroophthalmology 13, 183-189.
43. Tsacopoulos M., Evêquoz-Mercier V., Perrottet P. and Buchner E. (1988) Honeybee retinal glial cells transform glucose and supply the neurons with metabolic substrate. Proc. Natl Acad. Sci. U.S.A. 85, 8727-8731.
44. Tsacopoulos M., Veuthey A. L., Saravelos S. G., Perrottet P. and Tsoupras G. (1994) Glial cells transform glucose to alanine, which fuels the neurons in the honeybee retina. J. Neurosci. 14, 1339-1351.
45. Vannucci S. J. (1994) Developmental expression of GLUT1 and GLUT3 glucose transporters in brain. J. Neurochem. 62, 240-246.
46. Wolff J. R. (1970) The astrocyte as link between capillary and nerve cell. Triangle 9, 153-164.
47. Yu N. C., Martin J.-L. L., Stella N. and Magistretti P. J. (1993) Arachidonic acid stimulates glucose uptake in cerebral cortical astrocytes. Proc. Natl Acad. Sci. U.S.A. 90, 4042-4046.