Negative transcriptional regulation of PHO81 expression in Saccharomyces cerevisiae

Gene

Volumn 168, Issue 1, 1996, Pages 23-29

  Creasy, Caretha L ^a,b   Shao, Dalei ^a   Bergman, Lawrence W ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

Acid phosphatase; Gene fusion; Inhibitor; Promoter; Repression; Yeast

Indexed keywords

ACID PHOSPHATASE; GENE PRODUCT;

ARTICLE; GENE EXPRESSION; GENE FUSION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

EID: 0030070117     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(95)00737-7     Document Type: Article

References (22)

1. Bajwa, W., Meyhack, B., Rudolph, H., Schweingruber, A. and Hinnen, A.: Structural analysis of the two tandemly repeated acid phosphatase genes in yeast. Nucleic Acids Res. 12 (1984) 7721-7739.
2. Bergman, L.W.: A DNA fragment containing the upstream activator sequence determines nucleosome positioning of the transcriptionally repressed PHO5 gene of Saccharomyces cerevisiae. Mol. Cell. Biol. 6 (1986) 2298-2304.
3. Bostian, K.A., Lemire, J.M., Cannon, L.E. and Halvorson, H.O.: In vitro synthesis of repressible yeast acid phosphatase: identification of multiple mRNAs and products. Proc. Natl. Acad. Sci. USA 77 (1980) 4504-4508.
4. Creasy, C.L., Madden, S.L. and Bergman, L.W.: Molecular analysis of the PHO81 gene of Saccharomyces cerevisiae. Nucleic Acids Res. 21 (1993) 1975-1982.
5. Griggs, D.W. and Johnston, M.: Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression. Proc. Natl. Acad. Sci. USA 78 (1991) 8597-8601.
6. Guarente, L. and Ptashne, M.: Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 78 (1981) 2199-2203.
7. Hayashi, N. and Oshima, Y.: Specific cis-acting sequence of PHO8 expression interacts with Pho4 protein, a positive regulatory factor, in Saccharomyces cerevisiae. Mol. Cell. Biol. 11 (1991) 785-794.
8. Hirst, K., Fisher, F., McAndrew, P.C. and Goding, C.R.: The transcription factor, the Cdk, its cyclin and their regulator: directing the transcriptional response to a nutritional signal. EMBO J. 13 (1994) 5410-5420.
9. Kramer, R.A. and Andersen. N.: Isolation of yeast genes with mRNA levels controlled by phosphate concentration. Proc. Natl. Acad. Sci. USA 77 (1980) 6541-6545.
10. Koren, R., LeVitre, J. and Bostian, K.A.: Isolation of the positive-acting regulatory gene PHO4 from Saccharomyces cerevisiae. Gene 41 (1986) 271-280.
11. Lemire, J.M., Willcock, Y., Halvorson, H.O. and Bostian, K.A.: Regulation of repressible acid phosphatase gene transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 5 (1985) 2131-2141.
12. Luche, R.M., Sumrada, R. and Cooper, T.G.: A cis-acting element present in multiple genes serves as a represser protein binding site for the yeast CAR1 gene. Mol. Cell. Biol. 10 (1990) 3884-3895.
13. Ogawa, N., Noguchi, K., Yamashita, Y., Yasuhara, T., Hayashi, N., Yoshida, K. and Oshima, Y.: Promoter analysis of the PHO81 gene encoding a 134 kD protein bearing ankyrin repeats in the phosphatase regulon of Saccharomyces cerevisiae. Mol. Gen. Genet. 238 (1993) 444-454.
14. Park, H.-O. and Craig, E.A.: Positive and negative regulation of basal expression of a yeast HSP70 gene. Mol. Cell. Biol. 9 (1989) 2025-2033.
15. Rogers, D.T., Lemire, J.M. and Bostian, K.A.: Acid phosphatase polypeptides in Saccharomyces cerevisiae are encoded by a differentially regulated multgene family. Proc. Natl. Acad. Sci. USA 79 (1982) 2157-2161.
16. Schneider, K.R., Smith, R.L. and O'Shea, E.K.: Phosphate-regulated inactivation of the kinase Pho80-Pho85 by the CDK inhibitor Pho81. Science 266 (1994) 122-126.
17. Sikorski, R.S. and Hieter, P.: A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122 (1989) 19-27.
18. Thomas, D., Cherest, H. and Surdin-Kerjan, Y.: Elements involved in S-adenosylmethionine-mediated regulation of Saccharomyces cerevisiae: MET25 gene. Mol. Cell. Biol. 9 (1989) 3292-3298.
19. Toh-e, A. and Oshima. Y.: Characterization of a dominant constitutive mutation, PHOO, for the repressible acid phosphatase synthesis in Saccharomyces cerevisiae. J. Bacteriol. 120 (1974) 608-817.
20. Tohe, A., Ueda, Y., Kakimoto, S.-I. and Oshima, Y.: Isolation and characterization of acid phosphatase mutants in Saccharomyces cerevisiae. J. Bacteriol. 113 (1973) 727-738.
21. Yoshida, K., Kuromitsu, Z., Ogawa, N. and Oshima, Y.: Mode of expression of the positive regulatory genes PHO2 and PHO4 of the phosphatase regulon in Saccharomyces cerevisiae. Mol. Gen. Genet. 217 (1989a) 31-39.
22. Yoshida, K., Ogawa, N. and Oshima, Y.: Function of the PHO regulatory genes for repressible acid phosphatase synthesis. Mol. Gen. Genet. 217 (1989b) 40-46.