p53 overexpression and human papillomavirus infection in transitional cell carcinoma of the urinary bladder: Correlation with histological parameters

Journal of Pathology

Volumn 178, Issue 1, 1996, Pages 65-70

  Tenti, Patrizia ^a   Zappatore, Rita ^a   Romagnoli, Solange ^a   Civardi, Emilio ^b   Giunta, Paolo ^a   Scelsi, Roberto ^b   Stella, Giorgio ^c   Carnevali, Luciano ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b Clinical Pathology Service   (Italy)

^c General Hospital of Voghera   (Italy)

Author keywords

HPV; p53; Transitional cell carcinoma; Urinary bladder

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; BLADDER CARCINOMA; CANCER INVASION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PAPILLOMA VIRUS; PRIORITY JOURNAL; TRANSITIONAL CELL CARCINOMA; VIRUS INFECTION;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; BLOTTING, SOUTHERN; CARCINOMA, TRANSITIONAL CELL; COCARCINOGENESIS; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR VIRUS INFECTIONS; URINARY BLADDER NEOPLASMS;

EID: 0030069702     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199601)178:1<65::AID-PATH451>3.0.CO;2-W     Document Type: Article

References (24)

1. Soussi T, Legros Y, Lubin R, Ory K, Sehlichtholz B. Multifactorial analysis of p53 alteration in human cancer: a review. Int J Cancer 1994, 57: 1-9.
2. Bennett WP, Hollstein MC, Metcalf RA, et al. p53 mutation and protein accumulation during multistage human oesophageal carcinogenesis Cancer Res 1992; 52: 6092-6097.
3. Bartkova J, Bartek J, Lukas J, et al. p53 protein alterations in human testicular cancer including pre-invasive intratubular germ-cell neoplasia Int J Cancer 1991; 49: 196-202.
4. Bartek J, Bartkova J, Vojtesek B, et al Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro. Int J Cancer 1990; 46: 839-844.
5. Lassam NJ, From L, Kahn HJ. Overexpression of p53 is a late event in the development of malignant melanoma. Cancer Res 1993; 53: 2235-2238.
6. Sidransky D, Von Eschenbach A, Tsai YC, et al. Identification of p53 gene mutations in bladder cancers and urine samples. Science 1991; 252: 706-709.
7. Olumi AF, Tsai YC, Nichols PW, et al. Allelic loss of chromosome 17p distinguishes high grade from low grade transitional cell carcinomas of the bladder. Cancer Res 1990; 50: 7081-7083.
8. Fujimoto K, Yamada Y, Okajima E, et al Frequent association of p53 gene mutation in invasive bladder cancer. Cancer Res 1992, 52: 1393-1398.
9. Lipponen PK. Over-expression of p53 nuclear oncoprotein in transitional-cell bladder cancer and its prognostic value Int J Cancer 1993; 53: 365-370.
10. Esrig D, Spruck CH III, Nichols PW, et al p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumor grade, and stage in bladder cancer. Am J Pathol 1993; 143: 1389-1397.
11. Furihata M, Inoue K, Ohtsuki Y, Hashimoto H, Terao N, Fujita Y High-risk human papillomavirus infections and Overexpression of p53 protein as prognostic indicators in transitional cell carcinoma of the urinary bladder. Cancer Res 1993; 53: 4823-4827.
12. Sauter G, Deng G, Moch H, et al Physical deletion of the p53 gene in bladder cancer. Am J Pathol 1994; 144: 756-766.
13. Sarkis AS, Dalbagni G, Cordon-Cardo C, et al. Nuclear Overexpression of p53 protein in transitional cell bladder carcinoma, a marker for disease progression. J Natl Cancer Inst 1993, 85: 53-59.
14. Rotola A, Monini P, Di Luca D, et al. Presence and physical state of HPV DNA in prostate and urinary tract tissues. Int J Cancer 1992, 52: 359-365.
15. Anwar K, Naiki H, Nakakuki K, Inuzuka M. High frequency of human papillomavirus infection in carcinoma of the urinary bladder. Cancer 1992; 70: 1967-1973
16. Werness BA, Levine AJ, Howley PM. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 1990; 248: 76-79
17. Huibregtse JM, Scheffner M, Howley PM. Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotem with p53. Mol Cell Biol 1993, 13: 775-784
18. Mostofi FK, Sobin LH, Torloni H. Types Histologiques des Tumeurs de la Vessie Organisation Mondiale de la Santé Genève, 1974.
19. Vojtesek B, Bartek J, Midgley CA, Lane DP. An immunochcmical analysis of the human nuclear phosphoprotein p53 New monoclonal antibodies and epitope mapping using recombinant p53. J Immunol Methods 1992; 151: 237-244
20. Manos MM, Wright DK, Lewis AJ, Broker TR, Wolinsky SM The use of polymerase chain reaction amplification for the detection of genital human papillomavirus In. Furth M, Greaves M. eds Molecular Diagnostics of Human Cancer, Cancer Cells 7. Cold Spring Harbor. NY: Cold Spring Harbor Press, 1989; 209-214.
21. Cordon-Cardo C, Dalbagni G, Saez GT, et al. p53 mutations in human bladder cancer: genotypic versus phenotypic patterns-Int J Cancer 1994; 56: 347-353.
22. zur Hausen H. Fapillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers Cancer Res 1989, 49: 4677-4681.
23. Schalken JA, van Moorselaar RJA, Bringvier PP, Debruyne FMJ. Critical review of the models to study the biologic progression of bladder cancer Semin Surg Oncol 1992; 8: 274-278.
24. Spruck CH III, Ohneseit PF, Gonzales-Zulueta M, et al. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res 1994; 54: 784-788.