A mimetic of the RGDF-peptide [arginine-glycine-aspartic acid-phenylalanine] blocks aggregation and flow-induced platelet deposition on severely injured stenotic arterial wall. Effects on different animal models and in humans

Thrombosis Research

Volumn 81, Issue 1, 1996, Pages 101-112

  Pueyo, Carol ^a   Badimon, Juan J ^b   Royo, Teresa ^a   Feigen, Larry P ^c   Badimon, Lina ^a,d  

^a CSIC   (Spain)

^b Cardiovascular Institute   (United States)

^c PFIZER INC   (United States)

^d DEPT OF ENVIRONMENTAL CHEMISTRY   (Spain)

Author keywords

Aggregation; GPIIb IIIa; SC 49992; Stenosis

Indexed keywords

8 GUANIDINO OCTANOYL ASPARTIC ACID PHENYLALANINE; ANTICOAGULANT AGENT; ARGINYLGLYCYLASPARTYLPHENYLALANINE; FIBRINOGEN RECEPTOR; SC 49992; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY OCCLUSION; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DOG; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; STENOSIS; SWINE; THROMBOCYTE AGGREGATION;

AMINO ACID SEQUENCE; ANIMALS; DIPEPTIDES; DOGS; ENDOTHELIUM, VASCULAR; FIBRONECTINS; HUMANS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, VITRONECTIN; SWINE; THROMBOSIS; VITRONECTIN;

EID: 0030069661     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/0049-3848(95)00218-9     Document Type: Article

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