Expression of ubiquitin-like immunoreactivity in axons after compression trauma to rat spinal cord

Acta Neuropathologica

Volumn 91, Issue 2, 1996, Pages 155-160

  Li, G L ^a   Farooque, M ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Immunohistochemistry; Rat; Spinal cord; Trauma; Ubiquitin

Indexed keywords

UBIQUITIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; GRAY MATTER; IMMUNOHISTOCHEMISTRY; INJURY SCALE; MALE; NERVE FIBER; NERVE FIBER DEGENERATION; NERVE FIBER TRANSPORT; NONHUMAN; PARAPLEGIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT; PYRAMIDAL TRACT; RAT; SPINAL CORD COMPRESSION; SPINAL GANGLION; THORACIC SPINE; TRIGEMINUS GANGLION;

ANIMALS; AXONS; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; MALE; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL CORD INJURIES; UBIQUITINS;

EID: 0030069616     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050407     Document Type: Article

References (44)

1. Adams JH, Mitchell DE, Graham DI, Doyle D (1977) Diffuse brain damage of immediate impact type: its relationship to 'primary brain-stem damage' in head injury. Brain 100: 487-502
2. Adams JH, Graham DL Murray LS, Scott G (1982) Diffuse axonal injury due to nonmissile head injury in humans. Ann Neurol 12: 557-563
3. Ahrens P, Besancon F, Memet S, Ankel H (1990) Tumour necrosis factor enhances induction by beta-interferon of a ubiquitin cross-reactive protein. J Gen Virol 71: 1675-1682
4. Balentine JD (1978) Pathology of experimental spinal cord trauma. II. Ultrastructure of axons and myelin. Lab Invest 39: 254-265
5. Bizzi A, Schaetzle B, Patton A, Gambetti P, Autillo GL (1991) Axonal transport of the two major components of the ubiquitin system. Free ubiquitin and ubiquitin carboxyl-terminal hydrolase PGP9.5. Brain Res 548: 292-299
6. Bond V, Schlesinger MJ (1985) Ubiquitin is a heat shock protein in chicken embryo fibroblast. Mol Cell Biol 5: 949-956
7. Bond V, Schlesinger MJ (1986) The chicken ubiquitin gene contains a heat shock promoter and expresses an unstable mRNA in heat shocked cells. Mol Cell Biol 6: 4602-4610
8. Ciechanover A (1993) The ubiquitin-mediated proteolytic pathway. Brain Pathol 3: 67-75
9. Cochran E, Bacci B, Chen Y, Patton A, Gambetti P, Autilio-Gambetti L (1991) Amyloid precursor protein and ubiquitin immunoreactivity in dystrophic axons is not unique to Alzheimer's disease. Am J Pathol 139: 485-489
10. Dewar D, Graham D I, Teasdale G M. McCulloch J (1993) Alz-50 and ubiquitin immunoreactivity is induced by permanent focal cerebral ischaemia in the cat. Acta Neuropathol 86: 623-629
11. Finley D, Varshavsky A (1985) The ubiquitin system: functions and mechanisms. Trends Biochem Sci 10: 343-346
12. Goldstein G, Sheid M, Hammerling U, Boyse EA, Schlesinger DH, Haill HD (1975) Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells. Proc Natl Acad Sci USA 72: 11-15
13. Griffin JW, Price DL, Engel WK, Drachman DB (1977) The pathogenesis of reactive axonal swellings: role of axonal transport. J Neuropathol Exp Neurol 36: 214-227
14. Gultekin SH, Smith TW (1994) Diffuse axonal injury in craniocerebral trauma. A comparative histologic and immunohistochemical study. Arch Pathol Lab Med 118: 168-171
15. Hershko A (1991) The ubiquitin pathway for protein degeneration. Trends Neurosci 16: 265-268
16. Hershko A, Ciechanover A (1986) The ubiquitin pathway for the degeneration of intracellular proteins. Prog Nucleic Acid Res Mol Biol 33: 19-56
17. Holtz A (1989) Spinal cord compression injury. Acta Univ Ups 209: 1-43
18. Lampert P (1967) A comparative electron microscopic study of reactive, degenerating, regenerating and dystrophic axons. J Neuropathol Exp Neurol 26: 345-368
19. Lanteri-Minet M, Desmeules JA, Menetrey D (1993) Opposite effects of axon damage on heat shock proteins (hsp 70) and ubiquitin contents in motor neurons of neuropathic rats. Neurosci Lett 153: 49-52
20. Li GL, Farooque M Holtz A, Olsson Y (1995) Changes of ßamyloid precursor protein after compression trauma to the spinal cord: an experimental study in the rat using immunohistochemistry. J Neurotrauma 12: 269-277
21. Li GL, Farooque M, Holtz A, Olsson Y (1995) Microtubule-associated protein 2 as a sensitive marker for dendritic lesion after spinal cord trauma: an immunohistochemical study in the rat. Restor Neurol Neurosci 8: 189-197
22. Loeb KR, Haas AL (1994) Conjugates of ubiquitin cross-reactive protein distribute in a cytoskeletal pattern. Mol Cell Biol 14: 8408-8419
23. Lowe J, Mayer RJ (1990) Ubiquitin. cell stress and diseases of the nervous system. Neuropathol Appl Neurobiol 16: 281-291
24. Lowe J, Mayer RJ, Landon M (1993) Ubiquitin in neurodegenerative diseases. Brain Pathol 3: 55-65
25. Manetto V, Abdul-Karim FW, Perry G, Tabaton M. Autilio-Gambetti L, Gambetti P (1989) Selective presence of ubiquitin in intracellular inclusions. Am J Pathol 134: 505-513
26. Martin JE, Mather KS, Swash M, Garofalo O, Dale GE. Leigh PN, Anderton BH (1990) Spinal cord trauma in man: studies of phosphorylated neurofilament and ubiquitin expression. Brain 113, 1553-1562
27. Mayer RJ, Lowe J, Landon M, McDermott H, Tuckwell J, Doherty F, Laszlo L (1991) Ubiquitin and the lysosome system: molecular immunopathology reveals the connection. Biomed Biochim Acta 50: 333-341
28. Moretto G, Sparaco M, Monaco S, Bonetti B, Rizzuto N (1993) Cytoskeletal changes and ubiquitin expression in dystrophic axons of Seitelberger's disease. Clin Neuropathol 12: 34-37
29. Nyström B, Berglund JE, Bergquist E (1988) Methodological analysis of an experimental spinal cord compression model in the rat. Acta Neurol Scand 78: 460-466
30. Oppenheimer DR (1968) Microscopic lesion in the brain following head injury. J Neurol Neurosurg Psychiatry 31: 299-306
31. Parag HA, Raboy B, Kulga RG (1987) Effect of heat shock on protein degradation in mammalian cells: involvement of the ubiquitin system. EMBO J 6: 55-61
32. Peerless SJ, Rewcastle NB (1967) Shear injuries of the brain. Can Med Assoc J 96: 577-582
33. Perry G, Friedman R, Shaw G, Chau V (1987) Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc Natl Acad Sci USA 84: 3033-3036
34. Povlishock JT (1993) Traumatic brain injury. The pathobiology of injury and repair. In: Gorio A (ed) Neuroregeneration. Raven Press, New York, pp 185-216
35. Povlishock JT, Becker DP (1985) Fate of reactive axonal swellings induced by head injury. Lab Invest 52: 540-552
36. Povlishock JT, Becker DP, Cheng CLY. Vaughan GW (1983) Axonal change in minor head injury. J Neuropathol Exp Neurol 42: 225-242
37. Savedia S, Kieman JA (1994) Increased production of ubiquitin mRNA in motor neurons after axotomy. Neuropathol Appl Neurobiol 20: 577-586
38. Schueler PA, Eide RP (1988) Differential expression of ubiquitin within the rat brain. Discretely localized increases following salt loading. J Chem Neuroanat 1: 165-175
39. Schweitzer JB, Park MR, Einhaus SL. Robertson JT (1993) Ubiquitin marks the reactive swellings of diffuse axonal injury. Acta Neuropathol 85: 503-507
40. Sherriff FE, Bridges LR, Gentleman SM. Sivaloganathan S. Wilson S (1994) Markers of axonal injury in post mortem human brain. Acta Neuropathol 88: 433-439
41. Strich SJ (1961) Shearing of nerve fibers as a cause of brain damage due to head injury. Lancet II: 443-448
42. Strich SJ (1970) The pathology of brain damage due to blunt head injuries. In: Walter AECW. Critchley M (eds) The late effects of head injury. Thomas, Springfield, pp 501-524
43. Tomlinson BE (1970) Brain-stem lesions after head injury. J Clin Pathol (Suppl) 4: 154-165
44. Yaghmai A, Povlishock JT (1991) Traumatically induced reactive changes as visualized through the use of monoclonal antibodies targeted to the neurofitament subunits. J Neuropathol Exp Neurol 51: 158-176