Six different cytokines that share GP130 as a receptor subunit, induce serum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypothalamus-pituitary-adrenal axis by interleukin-1

Blood

Volumn 87, Issue 5, 1996, Pages 1851-1854

  Benigni, Fabio ^b   Fantuzzi, Giamila ^b   Sacco, Silvano ^b   Sironi, Marina ^b   Pozzi, Pietro ^b   Dinarello, Charles A ^b   Sipe, Jean D ^b   Poli, Valeria ^b   Cappelletti, Manuela ^b   Paonessa, Giacomo ^b   Pennica, Diane ^b   Panayotatos, Nikos ^b   Ghezzi, Pietro ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID A PROTEIN; CILIARY NEUROTROPHIC FACTOR; CORTICOSTERONE; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; ONCOSTATIN M; RECEPTOR SUBUNIT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOSTERONE RELEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN INDUCTION;

EID: 0030069456     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.5.1851.bloodjournal8751851     Document Type: Article

References (34)

1. Ip NY, Nye SH, Boulton TG, Davis S, Taga T, Li Y, Birren SJ, Yasukawa K, Kishimoto T, Anderson DJ, Stahl N, Yancopoulos GD: CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130. Cell 69:1121, 1992
2. Pennica D, Shaw KJ, Swanson TA, Moore MW, Shelton DL, Zioncheck KA, Rosenthal A, Taga T, Paoni NF, Wood WI: Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J Biol Chem, 270:10915, 1995
3. Pennica D, King KL, Shaw KJ, Luis E, Rullamas J, Luoh S-M, Darbonne WC, Knutzon DS, Yen R, Chien KR, Baker JB, Wood WI: Expression cloning of cardiotrophin-1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci USA 92:1142, 1995
4. Davis S, Aldrich TH, Valenzuela DM, Wong V, Furth ME, Squinto SP, Yancopulos GD: The receptor for ciliary neurotrophic factor. Science 253:59, 1991
5. Baumann H, Wong GG: Hepatocyte-stimulating factor III shares structural and functional identity with leukemia-inhibitory factor. J Immunol 143:1163, 1989
6. Gauldie J, Richards C, Harnish D, Lansdorp P, Baumann H: Interferon β2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci USA 84:7251, 1987
7. Richards CD, Brown TJ, Shoyab M, Baumann H, Gauldie J: Recombinant oncostatin M stimulates the production of acute phase proteins in hepG2 cells and primary hepatocytes in vitro. J Immunol 148:1731, 1992
8. Schooltink HT, Stoyan T, Roeb E, Heinrich PC, Rose-John S: Ciliary neurotrophic factor induces acute-phase protein expression in hepatocytes. FEBS Lett 314:280, 1992
9. Dittrich F, Thoenen H, Sendtner M: Ciliary neurotrophic factor: Pharmacokinetics and acute-phase response in rat. Ann Neurol 35:151, 1994
10. Mayer P, Geissler K, Ward M, Metcalf D: Recombinant human leukemia inhibitory factor induces acute phase proteins and raises the blood platelet counts in nohuman primates. Blood 12:3226, 1993
11. Libert C, Brouckaert P, Fiers W: Protection by α1-acid glycoprotein against tumor necrosis factor-induced lethality. J Exp Med 180:1571, 1994
12. Vogels MTE, Cantoni L, Carelli M, Sironi M, Ghezzi P, van der Meer JWM: Role of acute-phase proteins in interleukin-1-induced nonspecific resistance to bacterial infections in mice. Antimicrob Agents Chemother 37:2527, 1993
13. Shainkin-Kestenbaum R, Berlyne G, Zimlichman S, Sorin HR, Nyska M, Danon A: An acute phase protein, SAA, inhibits IL-1- and TNF-induced fever and hypothalamic PGE2 in mice. Scand J Immunol 34:179, 1991
14. 2 in brain but not in peripheral blood mononuclear cells. Brain Res 562:199, 1991
15. Shapiro L, Zhang X-X, Rupp RP, Wolff SM, Dinarello CA: Ciliary neurouophic factor is an endogenous pyrogen. Proc Natl Acad Sci USA 90:8614, 1993
16. Fantuzzi G, Benigni F, Sironi M, Conni M, Carelli M, Cantoni L, Shapiro L, Dinarello CA, Sipe JD, Ghezzi P: Ciliary neurotrophic factor induces SAA, hypoglycemia and anorexia, and potentiates IL-1-induced corticosterone and IL-6 production in mice. Cytokine 7:150, 1995
17. Besedovsky H, Del Rey A, Dinarello CA: Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 233:652, 1986
18. Fantuzzi G, Ghezzi P: Glucocorticoids as cytokine inhibitors: Role in neuroendocrine control and therapy of inflammatory diseases. Mediat Inflamm 2:263, 1993
19. Tobler A, Meier R, Seitz M, Dewald B, Baggiolini M, Fey MF: Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8 and IL-6 but not of M-CSF in human fibroblast. Blood 79:45, 1992
20. Perlstein RS, Mougey EH, Jackson WE, Neta R: Interleukin-1 and interleukin-6 act synergistically to stimulate the release of adrenocorticotropic hormone in vivo. Lymphokine Cytokine Res 10:141, 1991
21. Neta R, Perlstein R, Vogel SN, Ledney GD, Abrams J: Role of interleukin 6 (IL-6) in protection from lethal irradiation and in endocrine response to IL-1 and tumor necrosis factor. J Exp Med 175:689, 1992
22. Poli V, Balena R, Fattori E, Markatos A, Yamamoto M, Tanaka H, Ciliberto G, Rodan GA, Costantini F: Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion EMBO J 13:1189, 1994
23. Fattori E, Cappelletti M, Costa P, Sellitto C, Cantoni L, Carelli M, Faggioni R, Fantuzzi G, Ghezzi P, Poli V: Defective inflammatory response in IL-6 deficient mice. J Exp Med 180:1243, 1994
24. Sporeno E, Barbato G, Graziani R, Pucci P, Nitti G, Paonessa G: Production and structural characterization of amino terminally histidine tagged human oncostatin M in E. coli. Cytokine 6:255, 1994
25. Sironi M, Breviario F, Proserpio P, Biondi A, Vecchi A, Van Damme J, Dejana E, Mantovani A: IL-1 stimulates IL-6 production in endothclial cells. J Immunol 142:549, 1989
26. Sipe JD, Gonnerman WA, Loose LD, Knapschaefer G, Xie WJ, Franzblau C: Direct binding enzyme-linked immunosorbent assay (ELISA) for serum amyloid A (SAA). J Immunol Methods 125:125, 1989
27. Piquet-Pellorce C, Grey L, Mereau A, Heath JK: Are LIF and related cytokines functionally equivalent? Exp Cell Res 213:340, 1994
28. Davis S, Aldrich TH, Nancy I, Ip NY, Stahl N, Scherer S, Farruggella T, Di Stefano PS, Curtis R, Panayotatos N, Gascan H, Chevalier S, Yancopulos GD: Released form of CNTF receptor α component as a soluble mediator of CNTF responses. Science 259:1736, 1993
29. Kishimoto T, Taga T, Akira S: Cytokine signal transduction. Cell 76:253, 1994
30. Hack CE, De Groot ER, Felt-Bersma RJF, Nuijens JH, Van Schijndel RJMS, Eerenberg-Belmer AJM, Thijs LG, Aarden LA: Increased plasma levels of Inlerleukin-6 in sepsis. Blood 74:1704, 1989
31. Waring P, Wycherley K, Cary D, Nicola N, Metcalf D: Leukemia inhibitory factor levels are elevated in septic shock and various inflammatory body fluids. J Clin Invest 90:2031, 1992
32. Stockli KA, Lillien LE, Naher-Noe M, Breitfeld G, Hughes RA, Raff MC, Thoenen H, Sendtner M: Regional distribution, developmental changes, and cellular localization of CNTF-mRNA in the rat brain. J Cell Biol 115:447, 1991
33. Baumann H, Gauldie J: The acute phase response. Immunol Today 15:74, 1994
34. Dinarello CA, Cannon JG, Wolff SM, Bernheim HA, Beutler B, Cerami A: Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med 163:1433, 1986