Beneficial effects of allopurinol on glutathione levels and glutathione peroxidase activity in rat ischaemic acute renal failure

Journal of International Medical Research

Volumn 24, Issue 1, 1996, Pages 33-39

  Alatas O ^a   Sahin A ^a   Colak O ^a   Inal, M ^a   Koken T ^a   Yasar B ^a   Karahuseyinoglu E ^a  

^a ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; ALLOPURINOL; ASPARTATE AMINOTRANSFERASE; CREATININE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; XANTHINE OXIDASE;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY ISCHEMIA; KIDNEY VEIN; NONHUMAN; RAT; RENAL ARTERY; REPERFUSION; REPERFUSION INJURY; UREA NITROGEN BLOOD LEVEL;

ALKALINE PHOSPHATASE; ALLOPURINOL; ANIMALS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; BLOOD UREA NITROGEN; GAMMA-GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; KIDNEY; KIDNEY FAILURE, ACUTE; L-LACTATE DEHYDROGENASE; RATS; REPERFUSION INJURY;

EID: 0030069365     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/030006059602400105     Document Type: Article

References (18)

1. Wilkes BM, Mailloux LU: Acute renal failure pathogenesis and prevention. Am J Med 1986; 80: 1129-1136.
2. Gaudio KM, Siegel NJ: Pathogenesis and treatment of acute renal failure. Pediatr Clin North Am 1987; 34: 771-787.
3. Bulkley GB: Free radical mediated reperfusion injury: A selective review. Br J Cancer 1987; 55: 66-73.
4. Lynch MJ, Grum CM, Gallagher KP, et al: Xanthine oxidase inhibition attenuates ischemic reperfusion lung injury. J Surg Res 1988; 44: 538-544.
5. Parks DA, Granger DN: Ischemia-reperfusion injury: A radical view. Hepatology 1988; 8: 680-682.
6. Baker GL, Autor AP, Corry RJ: Effect of allopurinol on kidneys after ischemia and reperfusion. Curr Surg 1985; 42: 466-469.
7. Stewart JR, Crute SL, Loughlin V, et al: Prevention of free radical induced myocardial reperfusion injury with allopurinol. J Thorac Cardiovasc Surg 1985; 90: 68-72.
8. Garcia JG, Rollan CM, Enriquez MAR, et al: Improved survival in intestinal ischemia by allopurinol not related to xanthine oxidase inhibition. J Surg Res 1990; 48: 144-146.
9. Beutler E, Robson MJ, Buttenweiser E: The glutathione instability of drug sensitive red cells. J Lab Clin Med 1957; 49: 84-95.
10. Paglia DE, Valentine WN: Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967; 70: 158-169.
11. Kaufmann RP, Kobzik L, Shepto D, et al: Vasodilator prostaglandins prevent renal damage after ischemia. Ann Surg 1987; 205: 195-198.
12. 2 moderate postischemic renal failure. Surgery 1985; 98: 207-212.
13. Peterson DA, Kelly B, Gerrard JM: Allopurinol can act as an electron transfer agent. Is this relevant during reperfusion injury? Biochem Biophys Res Commun 1986; 137: 76-79.
14. Paller MS, Hoidal JR, Ferris TF: Oxygen free radicals in ischemic acute renal failure in the rat. J Clin Invest 1984; 74: 1156-1164.
15. Carmines PK, Bell PD, Roman RJ, et al: Prostaglandins in the sodium excretory response to altered renal arterial pressure in dogs. Am J Physiol 1985; 248: 8-14.
16. - in post hypoxic injury of renal epithelial cells. Am J Physiol 1992; 263: F251-F255.
17. Paller MS: Renal work, glutathione and susceptibility to free radical-mediated postischemic injury. Kidney Int 1988; 33: 843-849.
18. Yoshioka T, Bills T, Moore-Jarrett T, et al: Role of intrinsic antioxidant enzymes in renal oxidant injury. Kidney Int 1990; 38: 282-288.