Abnormal Purkinje cell dendrites in Lurcher chimeric mice result from a deafferentation-induced atrophy

Journal of Neurobiology

Volumn 29, Issue 3, 1996, Pages 330-340

  Soha, James M ^b   Herrup, Karl ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

cerebellum; deafferentation; granule cell; target dependent cell death

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CHIMERA; DEAFFERENTATION; DENDRITE; MOUSE; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL;

ANIMALS; ATROPHY; CELL DIVISION; CELL SIZE; CEREBELLUM; CHIMERA; DENDRITES; DENERVATION; FEMALE; MALE; MICE; MICE, NEUROLOGIC MUTANTS; NEURONS, AFFERENT; PHENOTYPE; PURKINJE CELLS;

EID: 0030069152     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4695(199603)29:3<330::AID-NEU5>3.0.CO;2-A     Document Type: Article

References (45)

1. ALTMAN, J. (1976a). Experimental reorganization of the cerebellar cortex. VI. Effects of X-irradiation schedules that allow or prevent cell acquisition after basket cells are formed. J. Comp. Neurol. 165:49-64.
2. ALTMAN, J. (1976b). Experimental reorganization of the cerebellar cortex. VII. Effects of late X-irradiation schedules that interfere with cell acquisition after stellate cells are formed. J. Comp. Neurol. 165:65-76.
3. AXELSSON, J. and THESLEFF, S. (1959). A study of supersensitivity in denervated mammalian skeletal muscle. J. Physiol. (Lond.) 147:178-193.
4. BARDE, Y.-A. (1989). Trophic factors and neuronal survival. Neuron 2:1525-1534.
5. BENES, F. M., PARKS, T. N., and RUBEL, E. W. ( 1977). Rapid dendritic atrophy following deafferentation: an EM morphometric analysis. Brain Res. 122:1-13.
6. BERRY, M. and BRADLEY, P. (1976). The growth of the dendritic tree of Purkinje cells in irradiated agranular cerebellar cortex. Brain Res. 116:361-387.
7. κ locus (Igk-J) as demonstrated by Southern hybridization and nucleotide sequence analysis. Immunogenetics 24:150-157.
8. BRADLEY, P. and BERRY, M. (1976). The effects of reduced climbing and parallel fibre input on Purkinje cell dendritic growth. Brain Res. 109:133-151.
9. BRADLEY, P. and BERRY, M. (1978a). The Purkinje cell dendritic tree in mutant mouse cerebellum. A quantitative Golgi study of weaver and staggerer mice. Brain Res. 142:135-141.
10. BRADLEY, P. and BERRY, M. (1978b). Quantitative effects of methylazoxymethanol acetate on Purkinje cell dendritic growth. Brain Res 143:499-511.
11. BROWN, M. C. and IRONTON, R. (1978). Sprouting and regression of neuromuscular synapses in partially denervated mammalian muscles. J. Physiol. (Lond.) 278:325-348.
12. CACERES, A. and STEWARD, O. (1983). Dendritic reorganization in the denervated dentate gyrus of the rat following entorhinal cortical lesions: a Golgi and electron microscopic analysis. J. Comp. Neurol. 214:387-403.
13. CADDY, K. W. T. and BISCOE, T. J. (1979). Structural and quantitative studies on the normal C3H and lurcher mutant mouse. Phil. Trans. R. Soc. Lond. B 287:167-201.
14. CADDY, K. W. T. and HERRUP, K. (1990). Studies of the dendritic tree of wild-type cerebellar Purkinje cells in lurcher chimeric mice. J. Comp. Neurol. 297:121-131.
15. CADDY, K. W. T. and HERRUP, K. (1991). The fine structure of the Purkinje cell and its afferents in lurcher chimeric mice. J. Comp. Neurol. 305:421-434.
16. CRUTCHER, K. A. and COLLINS, F. (1986). Entorhinal lesions result in increased nerve growth factor-like growth-promoting activity in medium conditioned by hippocampal slices. Brain Res. 399:383-389.
17. DEITCH, J. S. and RUBEL, E. W. (1984). Afferent influences on brain stem auditory nuclei of the chicken: time course and specificity of dendritic atrophy following deafferentation. J. Comp. Neurol. 229:66-79.
18. DUMESNIL-BOUSEZ, N. and SOTELO, C. (1992). Early development of the lurcher cerebellum: Purkinje cell alterations and impairment of synaptogenesis. J. Neurocytol. 21:506-529.
19. FAMBROUGH, D. M. (1970). Acetylcholine sensitivity of muscle fiber membranes: mechanism of regulation by motoneurons. Science 168:372-373.
20. GALL, C. and LYNCH, G. (1981). Fiber architecture of the dentate gyrus following ablation of the entorhinal cortex in rats of different ages: Evidence for two forms of axon sprouting in the immature brain. Neuroscience 6:903-910.
21. HENDELMAN, W. J. and AGGERWAL, A. S. (1980). The Purkinje neuron: I. A Golgi study of its development in the mouse and in culture. J. Comp. Neurol. 193: 1063-1079.
22. HERRUP, K. and SUNTER, K. (1987). Numerical matching during cerebellar development: quantitative analysis of granule cell death in staggerer mouse chimeras. J. Neurosci. 7:829-836.
23. JONES, W. H. and THOMAS, D. B. (1962). Changes in the dendritic organization of neurons in the cerebral cortex following deafferentation. J. Anat. 96:375-381.
24. KAPADIA, S. E. and LAMOTTE, C. C. (1987). Deafferentation-induced alterations in the rat dorsal horn: I. Comparison of peripheral nerve injury vs. rhizotomy effects on presynaptic, postsynaptic, and glial processes. J. Comp. Neurol. 266:183-197.
25. KRUEGER, B. K., BURNE, J. F., and RAFF, M. C. (1995). Evidence for large-scale astrocyte death in the developing cerebellum. J. Neurosci 15:3366-3374.
26. MINTZ, B. (1962). Formation of gcnotypically mosaic mouse embryos. Am. Zool 2:432.
27. MINTZ, B. (1965). Genetic mosaicism in adult mice of quadroparental lineage. Science 148:1232-1233.
28. MULLEN, R. J. and WHITTEN, W. K. (1971). Relationships of genotypes and degree of chimerism in coat color to sex ratios and gametogenisis in chimeric mice. J. Exp. Zool. 178:165-176.
29. NIEDERLE, B. and MAYR, R. (1978). Course of denervation atrophy in type I and type II fibres of rat extensor digitorum longus muscle. Anat Embryol. 153:9-21.
30. OPPENHEIM, R. W. (1991). Cell death during development of the nervous system. Annu. Rev. Neurosci 14: 453-501.
31. SADLER, M. and BERRY, M. (1989). Topological link-vertex analysis of the growth of Purkinje cell dendritic trees in normal, reeler, and weaver mice. J. Comp. Neurol. 289:260-283.
32. SOHA, J. M. and HERRUP, K. (1993). Purkinje cell dendrites in staggerer ↔ wild type mouse chimeras lack the aberrant morphologies found in lurcher ↔ wild type chimeras. J. Comp Neurol 331:540-550.
33. SOHA, J. M. and HERRUP, K. (1995). Stunted morphologies of cerebellar Purkinje cells in lurcher and staggerer mice are cell intrinsic effects of the mutant genes. J. Comp. Neurol. 357:65-75.
34. SOTELO, C. (1975). Dendritic abnormalities of Purkinje cells in the cerebellum of neurologic mutant mice (weaver and staggerer). Adv. Neurol. 12:335-351.
35. STANFIELD, B. B. and COWAN, M. (1982). The sprouting of septal afferents to the dentate gyrus after lesions of the entorhinal cortex in adult rats. Brain Res. 232: 162-170.
36. SWISHER, D. A. and WILSON, D. B. (1977). Cerebellar histogenesis in the lurcher (Lc) mutant mouse. J. Comp Neurol. 173:205-218.
37. TARKOWSKI, A. K. (1961). Mouse chimeras developed from fused eggs. Nature 190:357-360.
38. TRUNE, D. R. (1982). Influence of neonatal cochlear removal on the development of mouse cochlear nucleus: II. Dendritic morphometry of its neurons. J. Comp. Neurol. 209:425-434.
39. VOGEL, M. W. and HERRUP, K. (1989). Numerical matching in the mammalian CNS: lack of a competitive advantage of early over late generated cerebellar granule cells. J. Comp. Neurol 283:118-128.
40. VOGEL, M. W., SUNTER, K., and HERRUP, K. (1989). Numerical matching between granule and Purkinje cells in lurcher chimeric mice: a hypothesis for the trophic rescue of granule cells from target-related cell death. J. Neurosci. 9:3454-3462.
41. WEISS, G. M. and PYSH, J. J. (1978). Evidence for loss of Purkinje cell dendrites during late development: a morphometric Golgi analysis in the mouse. Brain Res. 154:219-230.
42. WETTS, R. and HERRUP, K. (1982a). Interaction of granule. Purkinje and inferior olivary neurons in lurcher chimaeric mice. I. Qualitative studies. J. Embryol. Exp. Morphol 68:87-98.
43. WETTS, R. and HERRUP, K. (1982b). Interaction of granule, Purkinje, and inferior olivary neurons in lurcher chimeric mice. II. Granule cell death. Brain Res. 250:358-362.
44. WETTS, R. and HERRUP, K. (1983). Direct correlation between Purkinje and granule cell number in the cerebella of lurcher chimeras and wild-type mice. Dev. Brain Res. 10:41-47.
45. WOODWARD, D. J., BICKETT, D., and CHANDA, R. (1975). Purkinje cell dendritic alterations after transient developmental injury of the external granular layer. Brain Res. 97:195-214.