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Volumn 40, Issue 1, 1996, Pages 191-195

Protection and rescue from 2′,3′-dideoxypyrimidine nucleoside analog toxicity by hemin in human bone marrow progenitor cells

Author keywords

[No Author keywords available]

Indexed keywords

3' AMINO 3' DEOXYTHYMIDINE; HEMIN; ZALCITABINE; ZIDOVUDINE;

EID: 0030069108     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.1.191     Document Type: Article
Times cited : (8)

References (36)
  • 3
    • 0025762185 scopus 로고
    • Eclectic mechanisms of heme regulation of hematopoiesis
    • Abraham, N. G., R. D. Levere, and J. D. Lutton. 1991. Eclectic mechanisms of heme regulation of hematopoiesis. Int. J Cell Clon 9:185-210
    • (1991) Int. J Cell Clon , vol.9 , pp. 185-210
    • Abraham, N.G.1    Levere, R.D.2    Lutton, J.D.3
  • 4
    • 0026324591 scopus 로고
    • Comparison of hemin enhancement of burst-forming units-erythroid clonal efficiency by progenitor cells from normal and HIV-infected patients
    • Abraham, N. G., A. Mathew, S. Jiang, J. D. Lutton, M. Nishimura, J. L. Chertkox, and R. D. Levere. 1991. Comparison of hemin enhancement of burst-forming units-erythroid clonal efficiency by progenitor cells from normal and HIV-infected patients Acta Haematol. 86:189-193.
    • (1991) Acta Haematol. , vol.86 , pp. 189-193
    • Abraham, N.G.1    Mathew, A.2    Jiang, S.3    Lutton, J.D.4    Nishimura, M.5    Chertkox, J.L.6    Levere, R.D.7
  • 6
    • 3242845175 scopus 로고
    • AIDS: Scientific progress, but no cure in sight
    • Baum, R. M. 1993 AIDS: scientific progress, but no cure in sight Chem. Eng. News July 5:20-27.
    • (1993) Chem. Eng. News July , vol.5 , pp. 20-27
    • Baum, R.M.1
  • 7
    • 0025870705 scopus 로고
    • Identification and comparison of CD34-positive cells and their subpopulations from normal peripheral blood and bone marrow using multicolor flow cytometry
    • Bender, J. G., K. L. Unverzagt, D. E. Walker, W. Lee, D. E. Van Epps, D. H. Smith, C. C. Stewart, and L. Bik To. 1991. Identification and comparison of CD34-positive cells and their subpopulations from normal peripheral blood and bone marrow using multicolor flow cytometry, Blood 77:2591-2596
    • (1991) Blood , vol.77 , pp. 2591-2596
    • Bender, J.G.1    Unverzagt, K.L.2    Walker, D.E.3    Lee, W.4    Van Epps, D.E.5    Smith, D.H.6    Stewart, C.C.7    Bik To, L.8
  • 8
    • 0014800912 scopus 로고
    • Methotrexate therapy of head and neck cancer improvement in therapeutic index by the use of leucovorin "rescue "
    • Capizzi, R. L., R. C. DeConti, J. C. Marsh, and J. R. Bertino. 1970. Methotrexate therapy of head and neck cancer improvement in therapeutic index by the use of leucovorin "rescue " Cancer Res. 30:1782-1788.
    • (1970) Cancer Res. , vol.30 , pp. 1782-1788
    • Capizzi, R.L.1    Deconti, R.C.2    Marsh, J.C.3    Bertino, J.R.4
  • 9
    • 0025766925 scopus 로고
    • Hemin stimulation of hemopoiesis in murine long-term bone marrow culture
    • Chertkov, J. L., S. Jiang, J. D. Lutton, R. D. Levere, and N. G. Abraham. 1991. Hemin stimulation of hemopoiesis in murine long-term bone marrow culture. Exp. Hematol 19:905-909.
    • (1991) Exp. Hematol , vol.19 , pp. 905-909
    • Chertkov, J.L.1    Jiang, S.2    Lutton, J.D.3    Levere, R.D.4    Abraham, N.G.5
  • 10
    • 0026071379 scopus 로고
    • Catabolism of 3́-azido-3́-deoxythyrnidine in hepatocytes and liver microsomes, with evidence of formation of 3′-amino-3′-deoxythymidine, a highly toxic catabolite for human bone marrow cells
    • Cretton, E. M., M.-Y. Xie, R. J. Bevan, N. M. Goudgaon, R. F. Schinazi, and J. P. Sommadossi. 1991 Catabolism of 3́-azido-3́-deoxythyrnidine in hepatocytes and liver microsomes, with evidence of formation of 3′-amino-3′-deoxythymidine, a highly toxic catabolite for human bone marrow cells Mol Pharm. 39:258-266.
    • (1991) Mol Pharm. , vol.39 , pp. 258-266
    • Cretton, E.M.1    Xie, M.-Y.2    Bevan, R.J.3    Goudgaon, N.M.4    Schinazi, R.F.5    Sommadossi, J.P.6
  • 11
    • 0028350971 scopus 로고
    • Three-dimensional structure-activity analysis of a series of porphyrin derivatives with anti-HIV-1 activity targeted to the V3 loop of the gp 120 envelope glycoprotein of the human immunodeficiency virus type 1
    • Debnath, A. K., S. Jiang, N. Strick, K. Lin, P. Haberfield, and A. R. Neurath. 1994. Three-dimensional structure-activity analysis of a series of porphyrin derivatives with anti-HIV-1 activity targeted to the V3 loop of the gp 120 envelope glycoprotein of the human immunodeficiency virus type 1. J. Med. Chem. 37:1099-1108.
    • (1994) J. Med. Chem. , vol.37 , pp. 1099-1108
    • Debnath, A.K.1    Jiang, S.2    Strick, N.3    Lin, K.4    Haberfield, P.5    Neurath, A.R.6
  • 12
    • 0028216549 scopus 로고
    • Effects of 2′,3′-dideoxynucleosides on proliferation and differentiation of human pluripotent progenitors in liquid culture and their effects on mitochondrial DNA synthesis
    • Faraj, A., D. A. Fowler, E. G. Bridges, and J. P. Sommadossi. 1994. Effects of 2′,3′-dideoxynucleosides on proliferation and differentiation of human pluripotent progenitors in liquid culture and their effects on mitochondrial DNA synthesis. Antimicrob. Agents Chemother. 38:924-930.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 924-930
    • Faraj, A.1    Fowler, D.A.2    Bridges, E.G.3    Sommadossi, J.P.4
  • 13
    • 0028007333 scopus 로고
    • Relationship between plasma concentrations of 3′-deoxy-3′-fluorothymidine (Alovudine) and antiretroviral activity in two concentration-controlled trials
    • Flexner, C., C. van der Horst, M. A. Jacobson, W. Powderly, and B. Polsky. 1994. Relationship between plasma concentrations of 3′-deoxy-3′-fluorothymidine (Alovudine) and antiretroviral activity in two concentration-controlled trials. J. Infect. Dis. 170:1394-1403.
    • (1994) J. Infect. Dis. , vol.170 , pp. 1394-1403
    • Flexner, C.1    Van Der Horst, C.2    Jacobson, M.A.3    Powderly, W.4    Polsky, B.5
  • 16
    • 0028207287 scopus 로고
    • Amelioration of azidothyidine-induced erythroid toxicity by hemin and stem cell factor in immune-suppressed mice
    • Hamburger, A. W., and R. B. Chen. 1904 Amelioration of azidothyidine-induced erythroid toxicity by hemin and stem cell factor in immune-suppressed mice. Exp. Hematol. 22:348-352.
    • (1904) Exp. Hematol. , vol.22 , pp. 348-352
    • Hamburger, A.W.1    Chen, R.B.2
  • 17
    • 0027143181 scopus 로고
    • Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment
    • Harrison, J., A. Kappas, R. D. Levere, J. D. Lutton, J. L. Chertkov, S. Jiang, and N. G. Abraham. 1993. Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment Blood 82: 3574-3579.
    • (1993) Blood , vol.82 , pp. 3574-3579
    • Harrison, J.1    Kappas, A.2    Levere, R.D.3    Lutton, J.D.4    Chertkov, J.L.5    Jiang, S.6    Abraham, N.G.7
  • 18
    • 0018838187 scopus 로고
    • The role of heme in the maturation of erythroblasts. The effects of inhibition of pyridoxine metabolism
    • Hoffman, L. M., and J. Ross. 1980. The role of heme in the maturation of erythroblasts. The effects of inhibition of pyridoxine metabolism. Blood 55:762-771.
    • (1980) Blood , vol.55 , pp. 762-771
    • Hoffman, L.M.1    Ross, J.2
  • 19
    • 0027330168 scopus 로고
    • Photofrin, but not benzoporphyrin derivative, stimulates hematopoiesis in the mouse
    • Hunt, D. W., R. A. Sorrenti, C. B. Smits, and J. G. Levy. 1993 Photofrin, but not benzoporphyrin derivative, stimulates hematopoiesis in the mouse. Immunopharmacology 26:203-212.
    • (1993) Immunopharmacology , vol.26 , pp. 203-212
    • Hunt, D.W.1    Sorrenti, R.A.2    Smits, C.B.3    Levy, J.G.4
  • 20
    • 0025358537 scopus 로고
    • Selective expression of CD45 isoforms on functional subpopulations of CD34+ hemopoietic cells from human bone marrow
    • Lansdorp, P. M., H. J. Sutherland, and C. J. Eaves. 1990. Selective expression of CD45 isoforms on functional subpopulations of CD34+ hemopoietic cells from human bone marrow. J. Exp. Med. 172:363-366.
    • (1990) J. Exp. Med. , vol.172 , pp. 363-366
    • Lansdorp, P.M.1    Sutherland, H.J.2    Eaves, C.J.3
  • 21
    • 0026032312 scopus 로고
    • Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine
    • Levere, R. D., Y.-F. Gong, A. Kappas, D. J. Bucher, G. P. Wormser, and N. G. Abraham. 1991. Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine. Proc. Natl Acad. Sci USA 88:1756-1759.
    • (1991) Proc. Natl Acad. Sci USA , vol.88 , pp. 1756-1759
    • Levere, R.D.1    Gong, Y.-F.2    Kappas, A.3    Bucher, D.J.4    Wormser, G.P.5    Abraham, N.G.6
  • 24
    • 0019987478 scopus 로고
    • Hemin enhances the in vitro growth of primitive erythroid progenitor cells
    • Monette, F. C., and A. S. Holden. 1982 Hemin enhances the in vitro growth of primitive erythroid progenitor cells. Blood 60:527-530
    • (1982) Blood , vol.60 , pp. 527-530
    • Monette, F.C.1    Holden, A.S.2
  • 25
    • 0021739351 scopus 로고
    • Specificity of hemin action in vivo at early stages of hematopoietic cell differentiation
    • Monette, F. C., S. A. Holden, M. J. Sheehy, and E. A. Matzinger. 1984. Specificity of hemin action in vivo at early stages of hematopoietic cell differentiation. Exp Hematol 12:782-787.
    • (1984) Exp Hematol , vol.12 , pp. 782-787
    • Monette, F.C.1    Holden, S.A.2    Sheehy, M.J.3    Matzinger, E.A.4
  • 28
    • 0027407484 scopus 로고
    • Nucleuside analogs: Similarities and differences
    • Sommadossi, J. P. 1993. Nucleuside analogs: similarities and differences Clin. Infect. Dis. 16(Suppl. 1):S7-S15.
    • (1993) Clin. Infect. Dis. , vol.16 , Issue.1 SUPPL.
    • Sommadossi, J.P.1
  • 29
    • 0023113366 scopus 로고
    • Toxicity of 3′-azido-3′-deoxythymidine and 9-(1.3-dihydroxy-2-propoxymethyl)guaninc for normal human hematopoictic progenitor cells in vitro
    • Sommadossi, J. P., and R. Carlisle. 1987. Toxicity of 3′-azido-3′-deoxythymidine and 9-(1.3-dihydroxy-2-propoxymethyl)guaninc for normal human hematopoictic progenitor cells in vitro Antimicrob Agents Chemother. 31:452-454.
    • (1987) Antimicrob Agents Chemother. , vol.31 , pp. 452-454
    • Sommadossi, J.P.1    Carlisle, R.2
  • 30
    • 0023788972 scopus 로고
    • Uridine reverses the toxicity of 3′-azido-3′-deoxythymidine in normal human granulocyte-macrophage progenitor cells in vitro without impairment of antiretroviral activity
    • Sommadossi, J. P., R. Carlisle, R. F. Schinazi, and Z. Zhou. 1988. Uridine reverses the toxicity of 3′-azido-3′-deoxythymidine in normal human granulocyte-macrophage progenitor cells in vitro without impairment of antiretroviral activity. Antimiciob. Agents Chemother 32:997-1001.
    • (1988) Antimiciob. Agents Chemother , vol.32 , pp. 997-1001
    • Sommadossi, J.P.1    Carlisle, R.2    Schinazi, R.F.3    Zhou, Z.4
  • 31
    • 0026471558 scopus 로고
    • Comparison of cytotoxicity of the (-)- And (+)-enantiomer of 2′.3′-dideoxy-3′-thiacytidine in normal human hone marrow progenitor cells
    • Sommadossi, J. P., R. F. Schinazi, C. K. Chu, and M. Y. Xie. 1902. Comparison of cytotoxicity of the (-)- and (+)-enantiomer of 2′.3′-dideoxy-3′-thiacytidine in normal human hone marrow progenitor cells Biochem Pharmacol. 44:1921-1925.
    • (1902) Biochem Pharmacol. , vol.44 , pp. 1921-1925
    • Sommadossi, J.P.1    Schinazi, R.F.2    Chu, C.K.3    Xie, M.Y.4
  • 32
    • 0003162547 scopus 로고
    • Novel pharmacologic approaches to the treatment of AIDS and potential use of uridine phosphorylase inhibitors
    • R B Diasio and J P Sommadossi (ed.), Pergamon Press, New York
    • Sommadossi, J. P., Z. Zhou, R. Carlisle, M. Y. Xie, D. A. Weidner, and M. H. el Kouni. 1990. Novel pharmacologic approaches to the treatment of AIDS and potential use of uridine phosphorylase inhibitors. p. 63-73. In R B Diasio and J P Sommadossi (ed.), Advances in chemotherapy of AIDS Pergamon Press, New York.
    • (1990) Advances in Chemotherapy of AIDS , pp. 63-73
    • Sommadossi, J.P.1    Zhou, Z.2    Carlisle, R.3    Xie, M.Y.4    Weidner, D.A.5    El Kouni, M.H.6
  • 33
    • 0025838078 scopus 로고
    • Human CD34+ HLA-DR- Bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis
    • Spour, E. F., J. E. Brandt, R. A. Briddell, T. Leemhuis, K. V. Besien, and R. Hoffman. 1991. Human CD34+ HLA-DR- bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis. Blood Cells 17:287-295.
    • (1991) Blood Cells , vol.17 , pp. 287-295
    • Spour, E.F.1    Brandt, J.E.2    Briddell, R.A.3    Leemhuis, T.4    Besien, K.V.5    Hoffman, R.6
  • 34
    • 0026635104 scopus 로고
    • Clinical pharmacokinetics of 3′-azido-3′-deoxythymidine (zidovudine) and catabolites with formation of a toxic catabolite, 3′-amino-3′-deoxythymidine
    • Stagg, M. P., E. M. Cretton, L. Kidd, R. B. Diasio, and J. P. Sommadossi. 1992. Clinical pharmacokinetics of 3′-azido-3′-deoxythymidine (zidovudine) and catabolites with formation of a toxic catabolite, 3′-amino-3′-deoxythymidine. Clin. Pharmacol. Ther. 51:668-676.
    • (1992) Clin. Pharmacol. Ther. , vol.51 , pp. 668-676
    • Stagg, M.P.1    Cretton, E.M.2    Kidd, L.3    Diasio, R.B.4    Sommadossi, J.P.5
  • 35
    • 0026605083 scopus 로고
    • Comparative effects of 3′-azido-3′-deoxythymidine and its metabolite, 3′-amino-3′-deoxythymidine, on hemoglobin synthesis in K-562 human leukemia cells Mol
    • Weidner, D. A., E. G. Bridges, E. M. Cretton, and J. P. Sommadossi. 1992. Comparative effects of 3′-azido-3′-deoxythymidine and its metabolite, 3′-amino-3′-deoxythymidine, on hemoglobin synthesis in K-562 human leukemia cells Mol. Pharmacol. 41:252-258.
    • (1992) Pharmacol. , vol.41 , pp. 252-258
    • Weidner, D.A.1    Bridges, E.G.2    Cretton, E.M.3    Sommadossi, J.P.4
  • 36
    • 0025694701 scopus 로고
    • 3′-Azido-3′-deoxythymidine inhibits globin gene transcription in butyric acid-induced K-562 human leukemia cells
    • Weidner, D. A., and J. P. Sommadossi, 1990. 3′-Azido-3′-deoxythymidine inhibits globin gene transcription in butyric acid-induced K-562 human leukemia cells. Mol. Pharmacol 38:797-804.
    • (1990) Mol. Pharmacol , vol.38 , pp. 797-804
    • Weidner, D.A.1    Sommadossi, J.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.