Phosphate administration increases both size and number of parathyroid cells in adult rats

Calcified Tissue International

Volumn 58, Issue 1, 1996, Pages 40-44

  Wang, Q ^a   Paloyan, E ^b   Parfitt, A M ^a  

^a HENRY FORD HOSPITAL   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Cell division; Hyperplasia; Hypertrophy; Morphometry

Indexed keywords

PHOSPHATE;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL DIVISION; CELL SIZE; FEMALE; MORPHOMETRICS; NONHUMAN; PARATHYROID CELL; PARATHYROID HORMONE RELEASE; PRIORITY JOURNAL; RAT;

EID: 0030069059     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02509544     Document Type: Article

References (24)

1. Slatopolsky E, Delmez JA (1994) Pathogenesis of secondary hyperparathyroidism. Am J Kidney Dis 23:229-236
2. Reiss E, Canterbury JM, Bercovilz MA, Kaplan EL (1970) The role of phosphate in the secretion of parathyroid hormone in man. J Clin Invest 49:2146-2149
3. Borle AB, Clark I (1981) Effects of phosphate-induced hyperparathyroidism and parathyroidectomy on the rat kidney calcium in vivo. Am J Physiol 241 (Endocrinol Metab 4):E136-E141
4. Drake TG, Albright F, Castleman B (1937) Parathyroid hyperplasia in rabbits produced by parenteral phosphate administration. J Clin Invest 16:203-206
5. Stoerk HC, Carnes WH (1945) The relation of the dietary Ca:P ratio to serum Ca and to parathyroid volume. J Nutr 29:43-50
6. Demeter JG, Jong SA, Oslapas R, Ernst K, Hessel P, Smith M, Nayyar R, Lawrence AM, Paloyan E (1991) High phosphate diet-induced primary hyperparathyroidism: an animal model. Surg 110:1053-1060
7. Wernerson A, Widholm SM, Svensson O, Reinholt FP (1991) Parathyroid cell number and size in hypocalcemic young rats. APMIS 99.1096-1102
8. Wernerson A, Svensson O, Reinholt FP (1989) Parathyroid cell number and size in hypocalcemic rats: a stereologic study employing modern unbiased estimators. J Bone Miner Res 4:705-713
9. Brandi ML, Fitzpatrick LA, Coon HG, Aurbach GD (1986) Bone parathyroid cells: cultures maintained for more than 140 population doublings. Proc Natl Acad Sci 83:1709-1713
10. Parfitt AM (1994) Parathyroid growth: normal and abnormal. In: Bilezikian JP, Levine MA, Marcus R (eds) The parathyroids - basic and clinical concepts. Raven Press, New York, pp 373-405
11. Gundersen HJG, Bendtsen TF, Korbo L, Marcussen N, Moller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A, West MJ (1988) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96:379-394
12. Gundersen HJG, Bagger P, Bendtsen TF, Evans SM, Korbo L, Marcussen N, Moller A, Nielsen K, Myengaard JR, Pakkenberg B, Sorensen FB, Vesterby A, West MJ (1988) The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 96:857-881
13. Capen CC, Roth SI (1973) Ultrastructural and functional relationships of normal and pathologic parathyroid cells. In: Ioachim HL (ed) Pathobiology annual. Appleton-Century-Crofts, New York, pp 129-175
14. Lloyd HM, Jacobi JM, Cooke RA (1979) Nuclear diameter in parathyroid adenomas. J Clin Pathol 32:1278-1281
15. Lloyd HM, Parfitt AM, Jacobi JM, Willgoss DA, Craswell PW, Petrie JJB, Boyle PD (1989) The parathyroid glands in chronic renal failure: a study of their growth and other properties, based on findings in hypocalcemic patients. J Lab Clin Med 114:358-367
16. Kerr JFR, Searle J, Harmon BV, Bishop CJ (1987) Apoptosis. In: Potten CS (ed) Perspectives on mammalian cell death. Oxford University Press, Oxford, pp 93-128
17. Platt H (1950) Mitotic activity in the parathyroid glands of the rat following bilateral nephrectomy. J Pathol Bacteriol 62:383-387
18. Hughes MR, Brumbaugh PF, Haussler MR, Werdegal JE, Baylink DJ (1975) Regulation of serum l-alpha,25-dihydroxyvitamin D3 by calcium and phosphate in the rat. Science 190:578-580
19. Portale AA, Halloran BP, Morris RC (1989) Physiologic regulation of the serum concentration of 1,25-dihydroxyvitamin D by phosphorus in normal men. J Clin Invest 83:1494-1499
20. Rodriguez M, Martin-Malo A, Martinez ME, Torres A, Felsenfeld AJ, Llach F (1991) Calcemic response to parathyroid hormone in renal failure: role of phosphorus and its effect on calcitriol. Kidney Int 40:1055-1062
21. Jacobi J, Lloyd HM, Meares JD (1977) Onset of oestrogeninduced prolactin secretion and DNA synthesis by the rat pituitary gland. J Endocrinol 72:35-39
22. Sakaguchi K (1994) Autocrine and paracrine functions of parathyroid tissue. In: Bilezikian JP, Levine MA, Marcus R (eds) The parathyroids-basic and clinical concepts. Raven Press, New York, pp 93-105
23. Hendy ON, Stotland MA, Grunbaum D, Fraher LJ, Loveridge N, Goltzman D (1989) Characteristics of secondary hyperparathyroidism in vitamin D-deficient dogs. Am J Physiol 256:E765-E772
24. Szabo A, Marke J, Beier E, Mall G, Ritz E (1989) 1,25(OH)2 vitamin D3 inhibits parathyroid cell proliferation in experimental uremia. Kidney Int 35:1049-1056