Pregnenolone sulfate increases intracellular Ca2+ levels in a pituitary cell line

European Journal of Pharmacology

Volumn 298, Issue 1, 1996, Pages 79-85

  Büküşoǧlu, Cüneyt ^a   Sarlak, Farzaneh ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Ca2+; GH3 cell; Pituitary; Pregnenolone sulfate; Steroid

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 5ALPHA PREGNANE 3,20 DIONE; ANDROSTANOLONE; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; COBALT CHLORIDE; ESTRADIOL; GALLOPAMIL; LANTHANUM CHLORIDE; NICARDIPINE; POTASSIUM CHLORIDE; PRASTERONE; PRASTERONE SULFATE; PREGNENOLONE; PREGNENOLONE SULFATE; PROGESTERONE; STEROID; TESTOSTERONE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL CLONE; CELL LINE; CELL STRAIN GH3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENTIATION; DRUG SPECIFICITY; HYPOPHYSIS CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; PITUITARY GLAND; PREGNENOLONE; RATS;

EID: 0030069036     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00772-5     Document Type: Article

References (43)

1. 1 rat pituitary cells, Endocrinology 116, 909.
2. 2+] concentrations to hormone secretion, J. Biol. Chem. 259, 15350.
3. Armstrong, C.M. and D.R. Matteson, 1985, Two distinct populations of calcium channels in a clonal line of pituitary cell, Science 227, 65.
4. Baulieu, E.E. and P. Robel, 1990, Neurosteroids: a new brain function, J. Steroid Biochem. Mol. Biol. 37, 395.
5. Blackmore, P.F., S.J. Beebe, D.R. Danforth and N. Alexander, 1990, Progesterone and 17α-hydroxyprogesterone. Novel stimulators of calcium influx in human sperm, J. Biol. Chem. 265, 1376.
6. Bowlby, M.R., 1993, Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons, Mol. Pharmacol. 43, 813.
7. Bukusoglu, C., J.G. Thalhammer and N.R. Krieger, 1993, Analgesia with anesthetic steroids and ethanol, Anesth. Analg. 77, 27.
8. 5-3β-hydroxysteroid levels in the fetoplacental circulation of normal pregnancy in labor and not in labor, J. Clin. Endorinol. Metab. 42, 744.
9. DePeretti, E. and E. Mappus, 1983, Pattern of plasma pregnenolone sulfate levels in humans from birth to adulthood, J. Clin. Endocrinol. Metab. 57, 550.
10. Dluzen, D.E. and V.D. Ramirez, 1987, Intermittent infusion of progesterone potentiates whereas continuous infusion reduces amphetamine-stimulated dopamine release from ovariectomized estrogen-primed rat striated fragments superfused in vitro, Brain Res. 406, 1.
11. Drouva, S.V., E. Laplante, J.P. Gautron and C. Kordon, 1984, Effects of 17β-estradiol on LH-RH release from rat mediobasal hypothalmic slices, Neuroendocrinology 38, 152.
12. Drouva, S.V., E. Laplante and C. Kordon, 1985, Progesterone-induced LH-RH release in vitro is an estrogen as well as and calmodulin-dependent secretory process, Neuroendocrinology 40, 325.
13. Dufy, B., J.-D. Vincent, H. Fleury, P.D. Pasquier, D. Gourdji and A. Tixier-Vidal, 1979, Membrane effects of thyrotropin-releasing hormone and estrogen shown by intracellular recording from pituitary cells, Science 204, 509.
14. 2+ agonist Bay K 8644 with normal and transformed pituitary cells, J. Am. Physiol. C95.
15. 2+ indicator, J. Biol. Chem. 269, 10141.
16. ffrench-Mullen, J.M.H., P. Danks and K. T. Spence, 1994, Neurosteroids modulate calcium currents in hippocampal CA1 neurons via a pertussis toxin-sensitive G-protein-coupled mechanism, J. Neurosci. 14, 1963.
17. 2+], Endocrinology 116, 591.
18. Grodal, S. and T. Curstedt, 1991, Steroid profile in serum: increased levels of sulfated pregnenlone and pregn-5-ene-3β,20α-diol in patients with adrenocortical carcinoma, Acta Endocrinol. (Copenhagen) 124, 381.
19. 2+] indicators with greatly improved fluorescence properties, J. Biol. Chem. 260, 3440.
20. Hirato, K. and T. Yanaihara, 1990, Serum steroid hormone levels in neonates born from the mother with placental sulfatase deficiency, Endorinol. Jpn. 37, 731.
21. 2+] in cultured rat hippocampal neurons, Neurosci. Lett. 141, 30.
22. Kojima, S., T. Yanaihara and T. Nakayama, 1981, Serum steroid levels in children at birth and in early neonatal period. Am. J. Obstet. Gynecol. 140, 961.
23. Kostyuk, P., N. Akaike, Y. Osipchuk, A. Sauchenko and Y. Shuba, 1989, Gating and permeation of different types of Ca channels, Ann. NY Acad. Sci. 560, 63.
24. Laatikainen, T. and J. Peltonen, 1975, Foetal and maternal plasma levels of steroid sulphates in human pregnancy at term, Acta Endocrinol. 79, 577.
25. Lanthier, A. and V.V. Patwardhan, 1986, Sex steroids and 5-en-5β-hydroxysteroids in specific regions of the human brain and cranial nerves, J. Steroid Biochem. 25, 445.
26. Liu, T.-C. and G.L. Jackson, 1985, Synthesis and release of luteinizing hormone in vitro by rat anterior pituitary cells: effects of gallopamil hydrochloride (D600) and pimozide, Endocrinology 117, 1608.
27. A receptor. Mechanism of action and physiological significance, Prog. Neurobiol. 38, 379.
28. Majewska, M.D. and R.D. Schwartz, 1987, Pregnenolone-sulfate: an endogenous antagonist of the γ-aminobutyric acid receptor complex in brain?, Brain Res. 404, 355.
29. McEwen, B.S., 1991, Non-genomic and genomic effects of steroids on neural activity, Trends Pharmacol. Sci. 12, 142.
30. Mok, W.M., S. Herschkowitz and N.R. Krieger, 1991, In vivo studies identify 5α-pregnan-3α-ol-20-one as an active anesthetic agent, J. Neurochem. 57, 1296.
31. Morley, P., J.F. Whitfield, B.C. Vanderhyden, B.K. Tsang and J.L. Schwartz, 1992, A new nongenomic estrogen action: the rapid release of intracellular calcium, Endocrinology 131, 1305.
32. Paul, S.M. and R.H. Purdy, 1992, Neuroactive Steriods, FASEB J. 6, 2311.
33. Phillips, G.H., 1975, Structure-activity relationship in steroidal anesthetics, J. Steroid Biochem. 6, 607.
34. Ramirez, V.D., D.E. Dluzen and F.C. Ke, 1990, Effects of progesterone and its metabolites on neuronal membranes, in: Steroids and Neuronal Activity, eds. D. Chadwick and K. Widdows, Ciba Foundation Symposium 153 (Wiley, Chichester) 125.
35. Shibuya, I. and W.W. Douglas, 1992, Calcium channels in rat melanotrophs are permeable to manganase, cobalt, cadmium and lanthanum but not to nickel: evidence provided by flourescence changes in fura-2-loaded cells. Endocrinology 131, 1936.
36. 2+ level in GH3 cells, J. Cell Physiol. 144, 62.
37. Thaw, C.N., E.G. Raaka and M.C. Gershengom, 1984, Evidence that cobalt ion inhibition of prolactin secretion occurs at an intracellular levels, Am. J. Physiol. 247, C150.
38. Triggle, D.J. and R.A. Janis, 1987, Calcium channel ligands, Annu. Rev. Pharmacol. Toxicol. 27, 347.
39. + channels. State-dependent interactions, J. Gen. Physiol. 103, 501.
40. Williams, D.A. and F.S. Fay, 1990, Intracellular calibration of the fluorescent calcium indicator Fura-2, Cell Calcium 44, 75.
41. Wu, F.-S., T.T. Gibbs and D.H. Farb, 1990, Inverse modulation of γ-aminobutyric acid-and glycine-induced currents by progesterone, Mol. Pharmacol. 37, 597.
42. Wu, F.S., T.T. Gibbs and D. H. Farb, 1991, Pregnenolone sulfate: A positive allosteric modulator at the N-tnethyl-D-aspartate receptor, Mol. Pharmacol. 40, 333.
43. Zar, J.H., 1984, Two-sample hypotheses, in: Biostatistical Analysis, ed. B. Kurtz, 2nd edn. (Prentice-Hall, Englewood Cliffs, NJ) p. 122.