Further genetic analysis of the activation function of the TyrR regulatory protein of Escherichia coli

Journal of Bacteriology

Volumn 178, Issue 4, 1996, Pages 1120-1125

  Yang, Ji ^a   Camakaris, H ^a   Pittard, A J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; ESCHERICHIA COLI; GENE ACTIVATION; GENE EXPRESSION; GENETIC ANALYSIS; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE;

EID: 0030068950     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.4.1120-1125.1996     Document Type: Article

References (27)

1. Andrews, A. E., B. Dickson, B. Lawley, C. Cobbett, and A. J. Pittard. 1991. Importance of the position of TYR R boxes for repression and activation of the tyrP and aroF genes of Escherichia coli. J Bacteriol. 173:5079-5085
2. Argyropoulos, V. P. 1989. Ph.D thesis. The University of Melbourne, Parkville, Australia.
3. Bartolomé, B., Y. Jubete, E. Martínez, and F. de la Cruz. 1991. Construction and properties of a family of pACYC184-derived cloning vectors compatible with pBR322 and its derivatives. Gene 102:75-78.
4. Chang, A. C. Y., and S. N. Cohen. 1978 Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid J Bacteriol. 134:1141-1156.
5. Cui, J., and R. L. Somerville. 1993. A mutational analysis of the structural basis for transcriptional activation and monomer-monomer interaction in the TyrR system of Escherichia coli K-12. J. Bacteriol. 175:1777-1784.
6. Cui, J., and R. L. Somerville. 1993 Mutational uncoupling of the transcriptional activation function of the TyrR protein of Escherichia coli K-12 from the repression function. J. Bacteriol. 175:303-306.
7. Cui, J., and R. L. Somerville. 1993. The TyrR protein of Escherichia coli. analysis by limited proteolysis of domain structure and ligand-mediated conformational changes. J. Biol. Chem. 268:5040-5047.
8. Greener, A., and M. Callahan. 1994. XL1-Red a highly efficient mutagenesis strain Strategies 7:32-34
9. Heatwole, V. M., and R. L. Somerville. 1991. The tryptophan-specific permease gene, mtr, is differentially regulated by the tryptophan and tyrosine repressors in Escherichia coli K-12. J Bacteriol. 173:3601-3604.
10. Kasian, P. A., and J. Pittard. 1984. Construction of a tyrP-lac operon fusion strain and its use in the isolation and analysis of mutants derepressed for tyrP expression. J. Bacteriol. 160:175-183.
11. Kieny, M. P., R. Lathe, and J. P. Lecocq. 1983. New versatile cloning and sequencing vectors based on bacteriophage M13. Gene 26:91-99.
12. Kolkhof, P., and B. Muller-Hill. 1994. Lambda c1 repressor mutants altered in transcriptional activation J. Mol. Biol. 242:23-36.
13. 70 promoters. Mol. Microbiol 17:471-481.
14. Lawley, B., N. Fujita, A. Ishibama, and A. J. Pittard. 1995. The TyrR protein of Escherichia coli is a class I transcription activator. J. Bacteriol. 177:238-241.
15. Messing, J., R. Crea, and P. H. Seeburg. 1981. A system for shotgun DNA sequencing Nucleic Acids Res. 9:309-321.
16. Miller, J. H. 1974. Experiments in molecular genetics, p. 352-355. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
17. Monod, J., G. Cohen-Bazire, and M. Cohen. 1951. Sur la biosynthese de la β-galactosidase (lactase) chez Eschericlna coli. La specificité de l'induction. Biochim. Biophys Acta 7:585-599.
18. Pittard, A. J., and B. E. Davidson. 1991. TyrR protein of Escherichia coli and its role as repressor and activator. Mol. Microbiol 5:1585-1592.
19. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a molecular laboratory manual, 2nd ed Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
20. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc Natl. Acad. Sci. USA 74:5463-5467.
21. Sarsero, J. P., and A. J. Pittard. 1991. Molecular analysis of the TyrR protein-mediated activation of mir gene expression in Escherichia coli K-12. J. Bacteriol 173:7701-7704.
22. Sarsero, J. P., P. J. Wookey, and A. J. Pittard. 1991. Regulation of expression of the Escherichia coli K-12 mtr gene by TyrR protein and Trp repressor. J. Bacteriol. 173:4133-4143.
23. Whipp, M. J., and A. J. Pittard. 1977. Regulation of aromatic amino acid transport systems in Escherichia coli K-12. J Bacteriol. 132:453-461.
24. Wilson, T. J., V. P. Argaet, G. J. Howlett, and B. E. Davidson. 1995. Evidence for two aromatic amino acid binding sites, one ATP-dependent and the other ATP-independent, in the Escherichia coli regulatory protein TyrR. Mol Microbiol. 17:483-492.
25. Yang, J., H. Camakaris, and A. J. Pittard. 1993. Mutations in the tyrR gene of Escherichia coli which affect TyrR-mediated activation but not TyrR-mediated repression. J. Bacteriol. 175:6372-6375.
26. Yang, J., S. Ganesan, J. Sarsero, and A. J. Pittard. 1993. A genetic analysis of various functions of the TyrR protein of Escherichia coli. J. Bacteriol. 175:1767-1776.
27. Yang, J., and J. Pittard. 1987. Molecular analyses of the regulatory region of the Escherichia coli K-12 tyrB gene. J. Bacteriol. 169:4710-1715.