Vaccination generates serum-mediated protection against Onchocerca lienalis microfilariae in the mouse

Tropical Medicine and International Health

Volumn 1, Issue 3, 1996, Pages 359-362

  Folkard, S G ^a   Jenkins, R E ^a   Bianco, A E ^a  

^a LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

infection; Onchocerca lienalis; vaccination

Indexed keywords

FREUND ADJUVANT; PARASITE ANTIGEN; PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; HOST RESISTANCE; HUMORAL IMMUNITY; INFECTION PREVENTION; INOCULATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICROFILARIA; MOUSE; NONHUMAN; ONCHOCERCA; ONCHOCERCIASIS; PASSIVE IMMUNIZATION; SERUM; SUBCUTANEOUS DRUG ADMINISTRATION; VACCINATION;

ANIMALIA; ONCHOCERCA; ONCHOCERCA LIENALIS;

EID: 0030068943     PISSN: 13602276     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3156.1996.d01-48.x     Document Type: Article

References (11)

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2. Bianco AE, Ham PJ, Sinnary EL & Nelson GS (1980) Large scale recovery of Onchocerca microfilariae from naturally infected cattle and horses. Transactions of the Royal Society for Tropical Medicine and Hygiene 74, 109-110.
3. Bianco AE, Nwachukwu MA, Townson S, Doenhoff MJ & Muller RL (1986) Evaluation of drugs against Onchocerca microfilariae in an inbred mouse model. Tropical Medicine and Parasitology 37, 39-45.
4. Carlow CKS & Bianco AE (1987) Resistance to Onchocerca lienalis microfilariae conferred by egg antigens of homologous and heterologous Onchocerca species. Parasitology 94, 485-496.
5. Folkard SG & Bianco AE (1995) Roles for both CD4+ and CD8+T cells in protective immunity against Onchocerca lienalis microfilariae in the mouse. Parasite Immunology 17, 541-553.
6. Folkard SG, Hogarth PJ, Taylor MJ & Bianco AE Eosinophils are the major effector cells of immunity to microfilariae in a mouse model of onchocerciasis. Parasitology (in press).
7. Kazura JW & Davis RS (1982) Soluble Brugia malayi microfilarial antigens protect against challenge by an antibody-dependent mechanism. Journal of Immunology 128, 1782-1792.
8. 4. Nature 227, 680-685.
9. Taylor MJ, Jenkins RE & Bianco AE Protective immunity induced by vaccination with Onchocerca volvulus tropomyosin in rodents. Parasite Immunology (in press).
10. Townson S & Bianco AE (1982) Experimental infection of mice with the microfilariae of Onchocerca lienalis. Parasitology 85, 283-293.
11. Townson S, Bianco AE, Doenhoff MJ & Muller RL (1984) Immunity to Onchocerca lienalis microfilariae in mice. I Resistance induced by the homologous parasite. Tropenmedizin und Parasitologie 35, 202-208.