Rectal absorption and mucosal irritation of rectal gels containing buprenorphine hydrochloride prepared with water-soluble dietary fibers, xanthan gum and locust bean gum

Journal of Controlled Release

Volumn 38, Issue 1, 1996, Pages 29-37

  Watanabe, Kazunori ^a,b   Yakou, Shigeru ^a   Takayama, Kozo ^b   Isowa, Koichi ^c   Nagai, Tsuneji ^b  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b HOSHI UNIVERSITY   (Japan)

^c Ctr of Japan Biol Chem Co Ltd   (Japan)

Author keywords

Buprenorphine; Dietary fiber; Hydrogel; Rectal absorption; Rectal irritation

Indexed keywords

ALGAROBA; BUPRENORPHINE; DRUG VEHICLE; MACROGOL; XANTHAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIETARY FIBER; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG RELEASE; GEL; HISTOPATHOLOGY; HYDROGEL; MALE; MEAN RESIDENCE TIME; NONHUMAN; PHARMACEUTICS; PRIORITY JOURNAL; RABBIT; RECTAL DRUG ADMINISTRATION; RECTUM; RECTUM INJURY;

EID: 0030068898     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(95)00096-8     Document Type: Article

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