Recent age-related trends in the use of thrombolytic therapy in patients who have had acute myocardial infarction

Annals of Internal Medicine

Volumn 124, Issue 3, 1996, Pages 283-291

  Gurwitz, Jerry H ^a   Gore, Joel M ^b   Goldberg, Robert J ^b   Rubison, Michael ^c   Chandra, Nisha ^d   Rogers, William J ^e  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c Southcreek Park   (United States)

^d JOHNS HOPKINS BAYVIEW MEDICAL CENTER   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; FIBRINOLYTIC AGENT; GLYCERYL TRINITRATE; HEPARIN; INOTROPIC AGENT;

ACUTE HEART INFARCTION; ADULT; AGE; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; FIBRINOLYTIC THERAPY; HOSPITALIZATION; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SEX DIFFERENCE; TIME;

EID: 0030068844     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-124-3-199602010-00001     Document Type: Article

References (37)

1. Udvarhelyi IS, Gatsonis C, Epstein AM, Pashos CL, Newhouse JP, McNeil BJ. Acute myocardial infarction in the Medicare population Process of care and clinical outcomes JAMA 1992,268 2530-6.
2. Maggioni AP, Maseri A, Fresco C, Franzosi MG, Mauri F, Santoro E, et al. Age-related increase in mortality among patients with first myocardial infarctions treated with thrombolysis. The Investigators of the Gruppo Italiano per lo Studio della Soprawivenza nell'Infarto Miocardico (GISSI-2). N Engl J Med. 1993,329:1442-8.
3. Gurwitz JH, Goldberg RJ, Chen Z, Gore JM, Alpert JS. Recent trends in hospital mortality of acute myocardial infarction - the Worcester Heart Attack Study Have improvements been realized for all age groups? Arch Intern Med 1994,154:2202-8.
4. Pashos CL, Newhouse JP, McNeil BJ. Temporal changes in the care and outcomes of elderly patients with acute myocardial infarction, 1987 through 1990. JAMA 1993;270:1832-6
5. Gurwitz JH, Goldberg RJ, Gore JM. Coronary thrombolysis for the elderly? JAMA 1991;265:1720-3.
6. Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI). Lancet 1986,1 397-402
7. Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction ISIS-2 ISIS-2 (Second International Study of Infarct Survival) Collaborative Group Lancet 1987;1:349-60
8. Effect of intravenous APSAC on mortality after acute myocardial infarction: preliminary report of a placebo-controlled clinical trial AIMS Trial Study Group Lancet. 1988;1.545-9.
9. Wilcox RG, von der Lippe G, Olsson CG, Jensen G, Skene AM, Hampton JR. Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction Anglo-Scandinavian Study of Early Thrombolysis (AS-SET) Lancet 1988,2 525-30
10. Indications for fibrinolytic therapy in suspected acute myocardial infarction. collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Fibrinolytic Therapy Trialists' (FTT) Collaborative Group Lancet 1994;343:311-22
11. Krumholz HM, Pasternak RC Weinstein MC, Friesinger GC, Ridker PM, Tosteson AH, et al. Cost effectiveness of thrombolytic therapy with streptokinase in elderly patients with suspected acute myocardial infarction N Engl J Med. 1992,3277-13.
12. Topol EJ, Califf RM. Thrombolytic therapy for elderly patients N Engl J Med 1992,327 45-7.
13. Rogers WJ. Contemporary management of acute myocardial infarction. Am J Med 1996;99:195-206
14. Goldberg RJ, Gurwitz J, Yarzebski J, Landon J, Gore JM, Alpert JS, et al. Patient delay and receipt of thrombolytic therapy among patients with acute myocardial infarction from a community-wide perspective. Am J Cardiol 1997,70421-5.
15. Pashos CL, Normand SL, Garfinkle JB, Newhouse JP, Epstein AM, McNeil BJ. Trends in the use of drug therapies in patients with acute myocardial infarction 1988 to 1992. J Am Coll Cardiol. 1994,23:1023-30
16. Pfeffer MA, Moye LA, Braunwald E, Basta L, Brown EJ Jr, Cuddy TE, et al. Selection bias in the use of thrombolytic therapy in acute myocardial infarction The SAVE Investigators. JAMA 1991,266528-32.
17. Krumholz HM, Friesinger GC Cook EF, Lee TH, Rouan GW, Goldman L. Relationship of age with eligibility for thrombolytic therapy and mortality among patients with suspected acute myocardial infarction J Am Geriatr Soc 1994;42 127-31
18. ACC Cardiovascular Norms Committee. Special report: practice panel survey results on acute myocardial infarction. Cardiology. 1992;21:5-6
19. Simoons ML, Maggioni AP, Knatterud G, Leimberger JD, de Jaegers P, van Domburg R, et al. Individual risk assessment for intracranial haemorrhage during thrombolytic therapy Lancet 1993;342:1523-8
20. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. The GUSTO Investigators N Engl J Med. 1993, 329-673-82
21. Rogers WJ, Bowiby LJ, Chandra NC, French WJ, Gore JM, Lambrew CT, et al. Treatment of myocardial infarction in the United States (1990 to 1993) Observations from the National Registry of Myocardial Infarction Circulation. 1994,90-2103-14
22. Walker SH, Duncan DB, Estimation of the probability of an event as a function of several independent variables. Biometrika 1967,54 167-79.
23. Gurwitz JH, Col NF, Avorn J. The exclusion of the elderly and women from clinical trials in acute myocardial infarction JAMA 1992;268:1417-22.
24. Wenger NK, Speroff L, Packard B. Cardiovascular health and disease in women. N Engl J Med. 1993,329247-56.
25. Weaver WD, Litwin PE, Martin JS, Kudenchuk PJ. Maynard C, Eisenberg MS, et al. Effect of age on use of thrombolytic therapy and mortality in acute myocardial infarction J Am Coll Cardiol. 1991;18 657-62
26. Gunnar RM, Passamani ER, Bourdillon PD, Pitt B, Dixon DW. Rapaport E, et al. Guidelines for the early management of patients with acute myocardial infarction A report of the American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures J Am Coll Cardiol 1990,16:249-92.
27. Gunnar RM, Bourdillon PD, Dixon DW, Fuster V, Karp RB, Kennedy JW, et al. ACC/AHA guidelines for the early management of patients with acute myocardial infarction A report of the American College of Cardiology/ American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures (subcommittee to develop guidelines for the early management of patients with acute myocardial infarction). Circulation 1990;82.664-707.
28. Kannel WB, Abbott RD. Incidence and prognosis of unrecognized myocardial infarction An update on the Framingham Study N Engl J Med. 1984, 311:1144-7
29. Medalie JH, Goldbourt U. Unrecognized myocardial infarction- five-year incidence, mortality, and risk factors. Ann Intern Med. 1976,84:526-31.
30. Sigurdsson E, Thorgeirsson G, Sigvaldason H, Sigfusson N. Unrecog nized myocardial infarction epidemiology, clinical characteristics, and the prognostic role of angina pectons. The Reykjavik Study. Ann Intern Med 1995,122.96-102.
31. Nadelmann J, Frishman WH, Ooi WL, Tepper D, Greenberg S, Guzik H, et al. Prevalence, incidence and prognosis of recognized and unrecognized myocardial infarction in persons aged 75 years or older: The Bronx Aging Study. Am J Cardiol 1990;66:533-7
32. Meehan TP, Hennen J, Radford MJ, Petrillo MK, Elstein P, Ballard DJ. Process and outcome of care for acute myocardial infarction among Medicare beneficiaries in Connecticut: a quality improvement demonstration project Ann Intern Med 1995,122.928-36
33. Ellerbeck EF, Jencks SF, Radford MJ, Kresowick TF, Graig AS, Gold JA, et al. Quality of care for Medicare patients with acute myocardial infarction A four-state pilot study from the Cooperative Cardiovascular Project. JAMA 1995;273:1509-14
34. Gurwitz JH, Goldberg RJ, Chen Z, Gore JM, Alpert JS. Beta-blocker therapy in acute myocardial infarction evidence for underutilization in the elderly Am J Med 1992,93 605-10.
35. Gurwitz JH. Food and Drug Administration (FDA) guideline for the study of drugs in elderly patients: an investigator and clinician perspective In: Wenger NK, ed Inclusion of Elderly Individuals in Clinical Trials. Cardiovascular Disease and Cardiovascular Therapy as a Model Kansas City: Marion Merrell Dow; 1993.205-12
36. Yarzebski J, Goldberg RJ, Gore JM, Alpert JS. Temporal trends and factors associated with extent of delay to hospital arrival in patients with acute myocardial infarction the Worcester Heart Attack Study. Am Heart J. 1994;128 255-63
37. Ayanian JZ, Hauptman PJ, Guadagnoli E, Antman EM, Pashos CL, McNeil BJ. Knowledge and practices of generalist and specialist physicians regarding drug therapy for acute myocardial infarction. N Engl J Med 1994; 331.1136-42