The synthesis and localization of alternatively spliced fibronectin EIIIB in resting and thrombin-treated megakaryocytes

Blood

Volumn 87, Issue 5, 1996, Pages 1817-1823

  Schick, Paul K ^a,b   Wojenski, Carol M ^a   Bennett, Vickie D ^a   Ivanova, Tamara ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; ISOPROTEIN; RNA; THROMBIN;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; GUINEA PIG; IMMUNOBLOTTING; MEGAKARYOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; THROMBOCYTE;

EID: 0030068686     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.5.1817.bloodjournal8751817     Document Type: Article

References (32)

1. Hynes RO: Fibronectins. Springer Series in Molecular Biology. New York, NY, Springer-Verlag, 1990, p 335
2. Schwarzbauer JE: Alternative splicing of fibronectin: Three variants, three functions. Bioessays 13:527, 1991
3. Mosher DF, Sottile J, Wu C, McDonald JA: Assembly of extracellular matrix. Cell Biol 4:810, 1992
4. Courtney MA, Stoler MH, Marder VJ, Haidaris PJ: Developmental expression of mRNAs encoding platelet proteins in rat megakaryocytes. Blood 77:560, 1991
5. Paul JI, Schwarzbauer JE, Tamkun JW, Hynes RO: Cell-type-specific fibronectin subunits generated by alternative splicing. J Biol Chem 26:12258, 1986
6. Nachman RL, Levine RF, Jaffe EA: Synthesis of factor VIII antigen by cultured guinea pig megakaryocytes. J Clin Invest 60:914, 1977
7. Handagama PJ, Shuman MA, Bainton DF: Incorporation of intravenously injected albumin, immunoglobulin G, and fibrinogen in guinea pig megakaryocyte granules. J Clin Invest 84:73, 1989
8. Peters JH, Trevithick JE, Johnson P, Hynes RO: Expression of the alternatively spliced EIIIB segment of fibronectin. Cell Adhes Comm 3:67, 1995
9. Schick PK, Schick BP: Methods for studying the biochemistry of recognizable megakaryocytes. Mod Methods Pharmacol 4:19, 1987
10. Schick PK, Williams-Gartner K, He X: Lipid composition and metabolism in megakaryocytes at different stages of maturation. J Lipid Res 31:27, 1990
11. Schick PK, Schick BP, Williams-Gartner K: Characterization of guinea pig megakaryocyte subpopulations at different phases of maturation prepared with a Celsep separation system. Blood 73:1801, 1989
12. Wojenski CM, Schick PK: Differences in thromboxane A2 synthesis by megakaryocytes and platelets. J Lab Clin Med 118:370, 1991
13. White DG, Hall JW, Branli DW, Gehris AL, Bennett VD: Chick cartilage fibronectin differs in structure from the fibronectin in limb mesenchyme. (submitted for publication)
14. Bennett VD, Pallante KM, Adams SL: The splicing pattern of fibronectin mRNA changes during chondrogenesis resulting in an unusual form of the mRNA in cartilage. J Biol Chem 266:5918, 1991
15. Schick PK, Filmyer W Jr: Sialic acid in mature megakaryocytes: Detection by wheat germ agglutinin. Blood 65:1120, 1985
16. Choi MG, Hynes RO: Biosynthesis and processing of fibronectin in NIL.8 hamster cells. J Biol Chem 254:12050, 1979
17. Magnuson VL, Young M, Schattenberg DG, Mancini MA, Chen D, Steffensen B, Klebe RJ: The alternative splicing of fibronectin pre-mRNA is altered during aging and in responses to growth factors. J Biol Chem 266:14654, 1991
18. Rencic A, Gehris AL, Lewis SD, Hume EL, Bennett VD: Splicing patterns of fibronectin mRNA from normal and osteoarthritic human articular cartilage. Osteoarthritis and Cartilage 3:187, 1995
19. Jarnagin WR, Rockey DC, Koteliansky VE, Wang S-S: Expression of variant fibronectin in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis J Cell Biol 127:2037, 1994
20. Peters JH, Sporn LE, Ginsber MH, Wagner DD: Human endothelial cells synthesize, process, and secrete fibronectin molecules bearing an alternatively-spliced type III homology (ED1). Blood 75:1801, 1990
21. Peters JH, Maunder RJ, Woolf AD, Cochrane CG, Ginsberg MH: Elevated plasma levels of ED1+ ("cellular") fibronectin in patients with vascular injury. J Lab Clin Med 113:586, 1989
22. Wagner DD, Marder VJ: Biosynthesis of von Willebrand protein by human endothelial cells. Processing steps and their intracellular localization. J Cell Biol 99:2123, 1984
23. Sporn LA, Chavin SI, Marder VJ, Wagner DD: Biosynthesis of von Willebrand protein by human megakaryocytes. J Clin Invest 76:1102, 1985
24. Preissner KT, Holzhuter S, Justus C, Muller-Berghaus G: Identification and partial characterization of platelet vitronectin: Evidence for complex formation with platelet-derived plasminogen activator inhibitor-1. Blood 74:1989, 1989
25. Hamilton R, Campbell FR: Immunochemical localization of extracellular materials in bone marrow of rats. Anat Rec 231:218, 1991
26. Coulombel L, Vuillet MH, Leroy C, Tchernia G: Lineage-and stage-specific adhesion of human hematopoietic progenitor cells to extracellular matrices from marrow fibroblasts. Blood 71:329, 1988
27. Tsai S, Patel V, Beaumont E, Lodish HF, Nathan DG, Sieff CA: Differential binding of erythroid and myeloid progenitors to fibroblasts and fibronectin. Blood 69:1587, 1987
28. Patel VP, Ciechanover A, Platt O, Lodish HF: Mammalian reticulocytes lose adhesion to fibronectin during maturation to erythrocytes. Proc Natl Acad Sci USA 82:440, 1985
29. Bockman DE, Gulati AK. Localization of fibronectin in megakaryocytes of fetal liver. Anat Rec 223:90, 1989
30. Leven RM, Mullikin WH, Nachmias VT: Role of sodium in ADP- and thrombin-induced megakaryocyte spreading. J Cell Biol 96:1234, 1983
31. Topp KS, Tablin F, Levin J: Culture of isolated bovine megakaryocytes on reconstituted basement membrane matrix leads to proplatelet process formation. Blood 76:912, 1990
32. Kuchinke W, Funk CD: Fibronectin-induced cell spreading and down-regulation of 12-lipoxygenase expression in megakaryocytic Dami cells. Biochem Biophys Res Commun 204:606, 1994