-
1
-
-
0025770218
-
Pharmacokinetics of ibuprofen enantiomers in dogs
-
Beck WS, Geisslinger G, Engler H, Brune K (1991) Pharmacokinetics of ibuprofen enantiomers in dogs. Chirality 3, 165-169
-
(1991)
Chirality
, vol.3
, pp. 165-169
-
-
Beck, W.S.1
Geisslinger, G.2
Engler, H.3
Brune, K.4
-
2
-
-
0026442409
-
Specific enantioselective sulfoxidation of an aryltrifluoromethyl sulfide by rat liver cytochromes P-450
-
Benoit E, Cresteil T, Riviere JL, Delatour P (1992) Specific enantioselective sulfoxidation of an aryltrifluoromethyl sulfide by rat liver cytochromes P-450. Drug Metab Dispos 20, 877-881
-
(1992)
Drug Metab Dispos
, vol.20
, pp. 877-881
-
-
Benoit, E.1
Cresteil, T.2
Riviere, J.L.3
Delatour, P.4
-
3
-
-
0028999153
-
(-)-R-Fenoprofen formation of fenoprofenyl-coenzyme A by rat liver microsomes
-
Benoit E, Delatour P, Olivier L, Caldwell J (1995) (-)-R-Fenoprofen formation of fenoprofenyl-coenzyme A by rat liver microsomes. Biochem Pharmacol 49, 1717-1720
-
(1995)
Biochem Pharmacol
, vol.49
, pp. 1717-1720
-
-
Benoit, E.1
Delatour, P.2
Olivier, L.3
Caldwell, J.4
-
4
-
-
0026072120
-
Presystemic and systemic chiral inversion of R(-)-fenoprofen in the rat
-
Berry BW, Jamali F (1991) Presystemic and systemic chiral inversion of R(-)-fenoprofen in the rat. J Pharmacol Exp Ther 25B, 695-701
-
(1991)
J Pharmacol Exp Ther
, vol.25 B
, pp. 695-701
-
-
Berry, B.W.1
Jamali, F.2
-
5
-
-
0021324781
-
Xenobiotic acyl-coenzymes A: Critical intermediates in the biochemical pharmacology and toxicology of carboxylic acids
-
Caldwell J (1984) Xenobiotic acyl-coenzymes A: critical intermediates in the biochemical pharmacology and toxicology of carboxylic acids Biochem Soc Trans 12, 9-11
-
(1984)
Biochem Soc Trans
, vol.12
, pp. 9-11
-
-
Caldwell, J.1
-
6
-
-
0023835819
-
The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences
-
Caldwell J, Hutt AJ, Fournel-Gigleux S (1988) The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences. Biochem Pharmacol 37, 105-114
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 105-114
-
-
Caldwell, J.1
Hutt, A.J.2
Fournel-Gigleux, S.3
-
7
-
-
0022002744
-
Ibuprofen stereoisomer hepatic clearance and distribution in normal and fatty in situ perfused rat liver
-
Cox JW, Cox SR, Vangiessen G, Ruwart MJ (1985) Ibuprofen stereoisomer hepatic clearance and distribution in normal and fatty in situ perfused rat liver. J Pharmacol Exp Ther 232, 636-643
-
(1985)
J Pharmacol Exp Ther
, vol.232
, pp. 636-643
-
-
Cox, J.W.1
Cox, S.R.2
Vangiessen, G.3
Ruwart, M.J.4
-
8
-
-
0017883185
-
The participation of ethyl 4-benzyloxybenzoate (BRL 10894)
-
Fears R, Baggaley KH, Alexander R, Organ B, Hindley RMM (1978) The participation of ethyl 4-benzyloxybenzoate (BRL 10894). J Lip Res 19, 3-11
-
(1978)
J Lip Res
, vol.19
, pp. 3-11
-
-
Fears, R.1
Baggaley, K.H.2
Alexander, R.3
Organ, B.4
Hindley, R.M.M.5
-
9
-
-
0023223333
-
High performance liquid chromatography assay of ketoprofen enantiomers in human plasma and urine
-
Foster RT, Jamali F (1987) High performance liquid chromatography assay of ketoprofen enantiomers in human plasma and urine. J Chromatogr Biomed Appl 416, 388-393
-
(1987)
J Chromatogr Biomed Appl
, vol.416
, pp. 388-393
-
-
Foster, R.T.1
Jamali, F.2
-
10
-
-
0026733690
-
Pulmonary inversion of 2-arylpropionic acids: Influence of protein binding
-
Hall SD, Hassanzanzadeh-Khayyat M, Knalder MP, Mayer PR (1992) Pulmonary inversion of 2-arylpropionic acids: influence of protein binding. Chirality 4, 349-352
-
(1992)
Chirality
, vol.4
, pp. 349-352
-
-
Hall, S.D.1
Hassanzanzadeh-Khayyat, M.2
Knalder, M.P.3
Mayer, P.R.4
-
11
-
-
0023143463
-
Enantioselective disposition of 2-arylpropionic acid nonsteroidal antiinflammatory drugs III. Fenoprofen disposition
-
Hayball PJ, Meffin PJ (1987) Enantioselective disposition of 2-arylpropionic acid nonsteroidal antiinflammatory drugs III. Fenoprofen disposition. J Pharmacol Exp Ther 240, 631-636
-
(1987)
J Pharmacol Exp Ther
, vol.240
, pp. 631-636
-
-
Hayball, P.J.1
Meffin, P.J.2
-
12
-
-
0021086740
-
The metabolic chiral inversion of 2-aryl-propionic acids - A novel route with pharmacological consequences
-
Hutt AJ, Caldwell J (1983) The metabolic chiral inversion of 2-aryl-propionic acids - a novel route with pharmacological consequences. J Pharm Pharmacol 35, 693-704
-
(1983)
J Pharm Pharmacol
, vol.35
, pp. 693-704
-
-
Hutt, A.J.1
Caldwell, J.2
-
13
-
-
0001913308
-
Amino acid conjugation
-
GJ Mulder, ed, Taylor and Francis, London
-
Hutt AJ, Caldwell J (1990) Amino acid conjugation. In: Conjugation Reactions in Drug Metabolism (GJ Mulder, ed), Taylor and Francis, London, 273-305
-
(1990)
Conjugation Reactions in Drug Metabolism
, pp. 273-305
-
-
Hutt, A.J.1
Caldwell, J.2
-
14
-
-
0025788606
-
The site of inversion of R(-)-ibuprofen. studies using rat in situ isolated perfused intestine/liver preparations
-
Jeffrey P, Tucker GT, Bye A, Crewe HK, Wrigth PA (1991) The site of inversion of R(-)-ibuprofen. studies using rat in situ isolated perfused intestine/liver preparations. J Pharm Pharmacol 43, 715-721
-
(1991)
J Pharm Pharmacol
, vol.43
, pp. 715-721
-
-
Jeffrey, P.1
Tucker, G.T.2
Bye, A.3
Crewe, H.K.4
Wrigth, P.A.5
-
15
-
-
0023694507
-
Enantiospecific formation of fenoprofen coenzyme A thioester in vitro
-
Knights KM, Drew R, Meffin PJ (1988) Enantiospecific formation of fenoprofen coenzyme A thioester in vitro. Biochem Pharmacol 37, 3539-3542
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 3539-3542
-
-
Knights, K.M.1
Drew, R.2
Meffin, P.J.3
-
16
-
-
0026516225
-
Inhibition kinetics of hepatic microsomal long chain fatty acid-CoA ligase by 2-arylpropionic acid non-steroidal anti-inflammatory drugs
-
Knights KM, Jones ME (1992) Inhibition kinetics of hepatic microsomal long chain fatty acid-CoA ligase by 2-arylpropionic acid non-steroidal anti-inflammatory drugs. Biochem Pharmacol 43, 1465-1471
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 1465-1471
-
-
Knights, K.M.1
Jones, M.E.2
-
17
-
-
0024787109
-
Chiral inversion of 2-arylpropionic acid non-steroidai drugs I
-
Knihinicki RD, Williams KM, Day RO (1989) Chiral inversion of 2-arylpropionic acid non-steroidai drugs I. Biochem Pharmacol 38, 4389-4395
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 4389-4395
-
-
Knihinicki, R.D.1
Williams, K.M.2
Day, R.O.3
-
19
-
-
0027070868
-
Variability of inversion of (R)-flurbiprofen in different species
-
Menzel S, Geisslinger G, Beck W, Brune K (1992) Variability of inversion of (R)-flurbiprofen in different species J Pharm Sci 81, 888-891
-
(1992)
J Pharm Sci
, vol.81
, pp. 888-891
-
-
Menzel, S.1
Geisslinger, G.2
Beck, W.3
Brune, K.4
-
20
-
-
0028059634
-
Is the formation of R-ibuprofenyi-adenylate the first stereoselective step of chiral inversion?
-
Menzel S, Waibel R, Brune K, Geisslinger G (1994) Is the formation of R-ibuprofenyi-adenylate the first stereoselective step of chiral inversion? Biochem Pharmacol 48, 1056-1058
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 1056-1058
-
-
Menzel, S.1
Waibel, R.2
Brune, K.3
Geisslinger, G.4
-
21
-
-
0022357211
-
Identity of long chain acyl coenzyme A. A synthetase of microsomes, mitochondria and peroxisomes in rat liver
-
Miyazawa S, Hashimoto T, Yokata S (1985) Identity of long chain acyl coenzyme A. A synthetase of microsomes, mitochondria and peroxisomes in rat liver. J Biochem (Tokyo) 204, 723-733
-
(1985)
J Biochem (Tokyo)
, vol.204
, pp. 723-733
-
-
Miyazawa, S.1
Hashimoto, T.2
Yokata, S.3
-
22
-
-
0025687875
-
Pharmacological aspects of chiral nonsteroidal anti-inflammatory drugs
-
Muller N, Payan E, Lapicque F, Bannwarth B, Netter P (1990) Pharmacological aspects of chiral nonsteroidal anti-inflammatory drugs. Fundam Clin Pharmacol 4, 617-634
-
(1990)
Fundam Clin Pharmacol
, vol.4
, pp. 617-634
-
-
Muller, N.1
Payan, E.2
Lapicque, F.3
Bannwarth, B.4
Netter, P.5
-
23
-
-
17044445025
-
Optical isomerisation mechanism of R(-)-hydratropic acid derivatives
-
Nakamura Y, Yamaguchi T, Takahashi S (1981) Optical isomerisation mechanism of R(-)-hydratropic acid derivatives. J Pharmacobiol Dyn 4, S-1
-
(1981)
J Pharmacobiol Dyn
, vol.4
-
-
Nakamura, Y.1
Yamaguchi, T.2
Takahashi, S.3
-
24
-
-
0020598354
-
A commentary: Methods and assumptions in the kinetic estimation of metabolite formation
-
Pang KS, Kwan KC (1983) A commentary: methods and assumptions in the kinetic estimation of metabolite formation. Drug Metab Dispos 11, 79-84
-
(1983)
Drug Metab Dispos
, vol.11
, pp. 79-84
-
-
Pang, K.S.1
Kwan, K.C.2
-
25
-
-
0022003825
-
Stereoselective inversion of (R)-fenoprofen to (S)-fenoprofen in humans
-
Rubin A, Knadler MP, Ho PPK, Bechtol LD, Wolen RL (1985) Stereoselective inversion of (R)-fenoprofen to (S)-fenoprofen in humans. J Pharm Sci 74, 82-84
-
(1985)
J Pharm Sci
, vol.74
, pp. 82-84
-
-
Rubin, A.1
Knadler, M.P.2
Ho, P.P.K.3
Bechtol, L.D.4
Wolen, R.L.5
-
26
-
-
0023947203
-
The stereospecific incorporation of fenoprofen into rat hepatocyte and adipocyte triacylglycerols
-
Sallustio BC, Meffin PJ, Knights M (1988) The stereospecific incorporation of fenoprofen into rat hepatocyte and adipocyte triacylglycerols Biochem Pharmacol 37, 1919-1923
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 1919-1923
-
-
Sallustio, B.C.1
Meffin, P.J.2
Knights, M.3
-
27
-
-
0027468764
-
Purification and characterization of novel '2-arylpropionyl-CoA' epimerases from liver cytosol and mitochondria
-
Shieh WR, Chen CS (1993) Purification and characterization of novel '2-arylpropionyl-CoA' epimerases from liver cytosol and mitochondria. J Biol Chem 268, 3487
-
(1993)
J Biol Chem
, vol.268
, pp. 3487
-
-
Shieh, W.R.1
Chen, C.S.2
-
28
-
-
0028360139
-
Taurine conjugation of ibuprofen in human and rat liver in vitro Relationship to metabolic chiral inversion
-
Shirley M, Guan X, Kaiser D, Halsted GW, Baillie TA (1994) Taurine conjugation of ibuprofen in human and rat liver in vitro Relationship to metabolic chiral inversion. J Pharmacol Exp Ther 269, 1166-1175
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 1166-1175
-
-
Shirley, M.1
Guan, X.2
Kaiser, D.3
Halsted, G.W.4
Baillie, T.A.5
-
29
-
-
0029053725
-
Comparative metabolism of R(-)-fenoprofen in rats and sheep
-
Soraci AL, Benoit E, Delatour P (1995) Comparative metabolism of R(-)-fenoprofen in rats and sheep. J Vet Pharmacol Ther 18, 167-171
-
(1995)
J Vet Pharmacol Ther
, vol.18
, pp. 167-171
-
-
Soraci, A.L.1
Benoit, E.2
Delatour, P.3
-
30
-
-
0029609667
-
In vitro fenoprofenyl-coenzyme A thioester formation: Interspecies variations
-
in press
-
Soraci AL, Benoit E (1995) In vitro fenoprofenyl-coenzyme A thioester formation: interspecies variations. Chirality (in press)
-
(1995)
Chirality
-
-
Soraci, A.L.1
Benoit, E.2
-
31
-
-
0018498892
-
Purification and properties of long-chain acyl-coenzyme-A synthetase from liver
-
Tanaka T, Hosaka K, Hoshimaru M, Numa S (1979) Purification and properties of long-chain acyl-coenzyme-A synthetase from liver. Eur J Biochem 98, 165-172
-
(1979)
Eur J Biochem
, vol.98
, pp. 165-172
-
-
Tanaka, T.1
Hosaka, K.2
Hoshimaru, M.3
Numa, S.4
-
32
-
-
0026782199
-
Formation of glycine conjugate and (-)-(R)-enantiomer from (+)-(S)-2-phenylpropionic acid suggesting the formation of the CoA thioester intermediate of (+)-(S)-enantiomer in dog
-
Tanaka Y, Shimomura T, Hirota T (1992) Formation of glycine conjugate and (-)-(R)-enantiomer from (+)-(S)-2-phenylpropionic acid suggesting the formation of the CoA thioester intermediate of (+)-(S)-enantiomer in dog. Chirality 4, 342-348
-
(1992)
Chirality
, vol.4
, pp. 342-348
-
-
Tanaka, Y.1
Shimomura, T.2
Hirota, T.3
-
33
-
-
0016351981
-
Enzymatic inversion at saturated carbon. nature and mechanism of the inversion of R(-)-p-isobutylhydratropic acid
-
Wechter WJ, Loughead DG, Reischer RJ, van Giessen GJ, Kaiser DG (1974) Enzymatic inversion at saturated carbon. nature and mechanism of the inversion of R(-)-p-isobutylhydratropic acid. Biochem Biophys Res Commun 61, 833
-
(1974)
Biochem Biophys Res Commun
, vol.61
, pp. 833
-
-
Wechter, W.J.1
Loughead, D.G.2
Reischer, R.J.3
Van Giessen, G.J.4
Kaiser, D.G.5
-
34
-
-
0022498370
-
The stereoselective uptake of ibuprofen enantiomers into adipose tissue
-
Williams KM, Day RO, Knihinicki RD, Duffield A (1986) The stereoselective uptake of ibuprofen enantiomers into adipose tissue. Biochem Pharmacol 35, 3403-3405
-
(1986)
Biochem Pharmacol
, vol.35
, pp. 3403-3405
-
-
Williams, K.M.1
Day, R.O.2
Knihinicki, R.D.3
Duffield, A.4
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