Methotrexate for refractory Crohn's disease: Preliminary answers to definitive questions

Mayo Clinic Proceedings

Volumn 71, Issue 1, 1996, Pages 104-105

  Kozarek, R A ^a  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; COTRIMOXAZOLE; CYCLOSPORIN; FOLIC ACID; MERCAPTOPURINE; MESALAZINE; METHOTREXATE;

ALLERGIC PNEUMONITIS; CLINICAL TRIAL; CROHN DISEASE; DRUG EFFICACY; DRUG SAFETY; EDITORIAL; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; LEUKOPENIA; LIVER TOXICITY; ORAL DRUG ADMINISTRATION; RHEUMATOID ARTHRITIS;

EID: 0030068458     PISSN: 00256196     EISSN: None     Source Type: Journal    
DOI: 10.4065/71.1.104     Document Type: Editorial

References (10)

1. RA Kozarek DJ Patterson MD Gelfand VA Botoman TJ Ball KR Wilske Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease Ann Intern Med 110 1989 353 356
2. TH Baron CD Truss CO Elson Low-dose oral methotrexate in refractory inflammatory bowel disease Dig Dis Sci 38 1993 1851 1856
3. C Chamiot-Prieur M Lémann B Mesnard M Halphen B Messing R Modigliani Treatment of refractory Crohn's disease (CD) with methotrexate (MTX) [abstract] Gastroenterology 104 1993 A680
4. S Arora WN Katkov J Cooley A Kemp RH Schapiro PB Kelsey A double-blind, randomized, placebo-controlled trial of methotrexate in Crohn's disease [abstract] Gastroenterology 102 1992 A591
5. RA Kozarek DJ Patterson MD Gelfand TJ Ball VA Botoman Long-term use of methotrexate in inflammatory bowel disease: severe disease 3, drug therapy 2; seventh inning stretch [abstract] Gastroenterology 1992 102:A648
6. SL Morgan JE Baggott WH Vaughn JS Austin TA Veitch JY Lee Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis: a doubleblind, placebo-controlled trial Ann Intern Med 121 1994 833 841
7. JM Kremer GS Alarcón RW Lightfoot Jr RF Willkens DE Furst HJ Williams Methotrexate for rheumatoid arthritis: suggested guidelines for monitoring liver toxicity Arthritis Rheum 37 1994 316 328
8. CM Stein T Pincus RH Brooks P Tugwell GA Wells D Yocum Combination therapy with cyclosporine and methotrexate: results of a 24 week extension study subsequent to a 24 week double-blind study [abstract] Arthritis Rheum 37 Suppl 1994 S252
9. P Tugwell T Pincus D Yocum G Wells R McKendry G Kraag A multi-centre, double-blind, randomized trial of low-dose cyclosporin and placebo therapy in combination with methotrexate in patients with severe rheumatoid arthritis [abstract] Arthritis Rheum 37 Suppl 1994 S361
10. TA Goodman RP Polisson Methotrexate: adverse reactions and major toxicities Rheum Dis Clin North Am 20 1994 May 513 528