Exocyclic amine of the conserved G·U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5′-splice site selection and transition state stabilization

Biochemistry

Volumn 35, Issue 4, 1996, Pages 1201-1211

  Strobel, Scott A ^a,b,d   Cech, Thomas R ^a,c  

^a UNIVERSITY OF COLORADO   (United States)

^b Life Sciences Research Foundation

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; CYTIDINE; GUANINE; INOSINE; RIBOZYME; RNA; URACIL;

ARTICLE; BASE PAIRING; ENZYME SUBSTRATE; EXON; HYDROGEN BOND; INTRON; NONHUMAN; PRIORITY JOURNAL; TETRAHYMENA; THERMODYNAMICS;

ANIMALS; BASE SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; EXONS; GUANOSINE; HYDROGEN BONDING; INTRONS; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; RNA SPLICING; RNA, CATALYTIC; SUBSTRATE SPECIFICITY; TETRAHYMENA; THERMODYNAMICS;

TETRAHYMENA;

EID: 0030068393     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952244f     Document Type: Article

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