Delineation of the peptide binding site of the human galanin receptor

EMBO Journal

Volumn 15, Issue 2, 1996, Pages 236-244

  Kask, Kalev ^a   Berthold, Malin ^a   Kahl, Ulrika ^a   Nordvall, Gunnar ^b   Bartfai, Tamas ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b Astra Arcus AB   (Sweden)

Author keywords

Galanin; Ligand binding; Molecular modelling; Receptor; Site directed mutagenesis

Indexed keywords

BACTERIORHODOPSIN; DRUG CARRIER; GALANIN; GALANIN RECEPTOR; MEMBRANE PROTEIN; ZINC;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROGEN BOND; LIGAND BINDING; MOLECULAR CLONING; MOLECULAR MODEL; POINT MUTATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

EID: 0030068285     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00354.x     Document Type: Article

References (45)

1. Baldwin, J. (1993) EMBO J., 12, 1693-1703.
2. Bartfai, T., Hökfelt, T. and Langel, Ü. (1993a) Crit. Rev. Neurobiol., 7, 229-274
3. Bartfai, T et al. (1993b) Proc. Natl Acad. Sci USA, 90, 11287-11291.
4. Bauer, F.E., Ginsberg, L., Venetikou, M , MacKay, D.J., Burrin, J.M. and Bloom, S.R. (1986) Lancet, 2, 192-194.
5. Bedecs, K , Langel, Ü. and Bartfai, T. (1995) Neuropeptides, 29, 137-143.
6. Beinborn, M., Lee, Y.M., McBride, E.W., Quinn, S.M. and Kopin, A.S. (1993) Nature, 362, 348-350.
7. Benelli, A., Arletti, R., Bertolini, A., Menozzi, B., Basaglia, R. and Poggioli, R. (1994) Eur. J. Pharmacol., 260, 279-282.
8. Clackson, T. and Wells, J.A. (1995) Science, 267, 383-386.
9. Elling, C.E., Nielsen, S.M. and Schwartz, T.W. (1995) Nature, 374, 74-77.
10. Evans, C J , Keith, D.E.J., Morrison, H., Magendzo, K. and Edwards, R.H. (1992) Science, 258, 1882-1884
11. Evans, H.F. and Shine, J. (1991) Endocrinology, 129, 1682-1684.
12. Fathi, Z., Benya, R.V., Shapira, H., Jensen, R.T. and Battey, J.F. (1993) J. Biol. Chem., 268, 14622-14626.
13. Fisone, G. et al. (1989a) Proc. Natl Acad. Sci. USA, 86, 9588-9591.
14. Fisone, G., Langel, Ü., Carlquist, M., Bergman, T., Consolo, S., Hökfelt, T., Undén, A., Andell, S. and Bartfai, T. (1989b) Eur. J. Biochem., 181, 269-276.
15. Fong, T M., Yu, H., Huang, R.R. and Strader, C.D. (1992) Biochemistry, 31, 11806-11811.
16. Fong, T.M., Cascieri, M.A., Yu, H., Bansal, A., Swain, C. and Strader, C.D. (1993) Nature, 362, 350-353.
17. Gether, U , Johansen, T E., Snider, R.M., Lowe, J., III, Nakanishi, S and Schwartz, T.W. (1993) Nature, 362, 345-348.
18. Habert-Ortoli, E., Amiranoff, B., Loquet, I., Laburthe, M. and Mayaux, J.-F. (1994) Proc. Natl Acad. Sci. USA, 91, 9780-9783.
19. Henderson, R., Baldwin, J.M., Ceska, T.A., Zemlin, F., Beckmann, E. and Downing, K.H. (1990) J. Mol. Biol., 213, 899-929.
20. Heuillet, E. et al. (1994) Eur. J. Pharmacol. Mol. Pharm., 269, 139-147.
21. Kaupmann, K., Bruns, C., Raulf, F., Weber, H.P., Mattes, H. and Lübbert, H. (1995) EMBO J., 14, 727-735.
22. Lagny-Pourmir, I., Lorinet, A.M , Yanaihara, N. and Laburthe, M. (1989) Peptides, 10, 757-761.
23. Land, T., Langel, Ü., Löw, M., Berthold, M., Undén, A. and Bartfai, T. (1991) Int. J. Peptide Protein Res., 38, 267-272
24. Leibowitz, S.F. and Kim, T. (1992) Brain Res., 599, 148-152.
25. Lorinet, A M., Javoyagid, F., Laburthe, M. and Amiranoff, B. (1994) Eur. J. Pharmacol. Mol. Pharm., 269, 59-64.
26. McDonald, T.J., Dupreé, J., Tatemoto, K., Greenberg, G.R., Radziuk, J. and Mutt, V. (1985) Diabetes, 34, 192-196.
27. Merchenthaler, I., López, F.J. and Negrovilar, A. (1993) Prog. Neurobiol., 40, 711-769.
28. Morris, M.B., Ralston, G.B., Biden, T.J , Browne, C.L., King, G.F. and Iismaa, T P. (1995) Biochemistry, 34, 4538-4545.
29. Nordvall, G. and Hacksell, U. (1993) J. Med. Chem., 36, 967-976.
30. Ögren, S.O , Hökfelt, T , Kask, K., Langel, U. and Bartfai, T. (1992) Neuroscience, 51, 1-5.
31. Peterson, G.L (1977) Anal. Biochem., 83, 346-356.
32. Rossowski, W.J , Rosowski, T.M , Zacharia, S., Ertan, A. and Coy, D.H. (1990) Peptides, 11, 333-338
33. Schall, T.J. et al. (1990) Cell, 62, 361-370.
34. Schambye, H.T., Hjorth, S.A., Bergsma, D.J , Sathe, G and Schwartz, T.W. (1994) Proc Natl Acad. Sci. USA, 91, 7046-7050.
35. Schambye, H.T , Hjorth, S.A., Weinstock, J. and Schwartz, T.W. (1995) Mol Pharmacol., 47, 425-431.
36. Schertler, G.F., Villa, C. and Henderson, R. (1993) Nature, 362, 770-772.
37. Schwartz, T.W. (1994) Curr. Opin. Biotechnol., 5, 434-444.
38. Takasuka, T., Sakurai, T., Goto, K., Furuichi, Y. and Watanabe, T. (1994) J. Biol. Chem , 269, 7509-7513.
39. Tatemoto, K., Rökaeus, A., Jörnvall, H., McDonald, T.J. and Mutt, V. (1983) FEBS Lett., 164, 124-128.
40. Unger, V.M and Schertler, G.F.X. (1995) Biophys. J., 68, 1776-1786.
41. Wang, J.B., Johnson, P.S., Wu, J.M., Wang, W F. and Uhl, G.R. (1994) J. Biol Chem., 269, 25966-25969.
42. Wennerberg, A.B., Cooke, R.M., Carlquist, M., Rigler, R. and Campbell, I.D. (1990) Biochem Biophys. Res Commun., 166, 1102-1109.
43. Wiesenfeld-Hallin, Z., Xu, X.J., Langel, Ü., Bedecs, K., Hökfelt, T. and Bartfai, T. (1992) Proc. Natl Acad. Sci. USA, 89, 3334-3337.
44. Wynick, D., Smith, D.M., Ghatei, M., Akinsanya, K., Bhogal, R., Purkiss, P., Byfield, P., Yanaihara, N. and Bloom, S R. (1993) Proc. Natl Acad. Sci. USA, 90, 4231-4235.
45. Xu, Y., Song, J., Bruno, J.F. and Berelowitz, M. (1993) Biochem. Biophys. Res. Commun., 193, 648-652.